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All Studies   Meta Analysis   Recent: 
COVID-19 and heme oxygenase: novel insight into the disease and potential therapies
Hooper, P., Cell Stress and Chaperones, doi:10.1007/s12192-020-01126-9 (Theory)
4 Jun 2020    Source   PDF   Share   Tweet
Proposal that COVID-19 risk is related to low intracellular heme oxygenase (HO-1), and that therapies that raise HO-1 may be beneficial, which includes fluvoxamine, certain anesthetics (sevoflurane or isoflurane), hemin, estrogen, statins, curcumin, resveratrol, and melatonin. Authors note that cigarette smoke is associated with increased HO-1 in lung fibroblasts and vascular endothelial cells, which may help explain the lower risk for smokers seen in several studies.
Hooper et al., 4 Jun 2020, peer-reviewed, 1 author.
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