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All Studies   Meta Analysis    Recent:   

Probiotics for preventing acute upper respiratory tract infections

Hao et al., Cochrane Database of Systematic Reviews, doi:10.1002/14651858.CD006895.pub3
Feb 2015  
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Probiotics for COVID-19
18th treatment shown to reduce risk in March 2021
 
*, now with p = 0.0000011 from 28 studies.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,800+ studies for 98 treatments. c19early.org
Meta analysis of 12 RCTs with 3,720 patients showing probiotics reduced acute upper respiratory tract infections.
2 meta analyses show significant improvements with probiotics for hospitalization1 and recovery1,2.
Currently there are 28 probiotics for COVID-19 studies, showing 59% lower mortality [35‑74%], 38% lower ventilation [-87‑79%], 21% lower ICU admission [-20‑48%], 13% lower hospitalization [5‑21%], and 36% fewer cases [7‑55%].
Hao et al., 3 Feb 2015, preprint, 3 authors.
This PaperProbioticsAll
Probiotics for preventing acute upper respiratory tract infections
Qiukui Hao, Bi Rong Dong, Taixiang Wu
Cochrane Database of Systematic Reviews, doi:10.1002/14651858.cd006895.pub3
Trusted evidence. Informed decisions. Better health.
Cochrane Library Trusted evidence. Informed decisions. Better health. Cochrane Database of Systematic Reviews Age: aged 18 to 65 Inclusion criteria: healthy volunteers Exclusion criteria: known intolerance or allergy to any ingredient included in the formulations, medically treated allergy, current treatment for severe gastrointestinal disorders, pregnancy or lactation, vaccination against influenza within the last 12 months or smoking Interventions Treatment group: Lactobacillus plantarum HEAL 9 and Lactobacillus paracasei 8700:2 (1 × 10 9 CFU/day) for 12 weeks Control group: placebo: an identical-looking and tasting control product Cochrane Database of Systematic Reviews 3. Symptom score (burden) Notes - Risk of bias C O N T R I B U T I O N S O F A U T H O R S Qiukui Hao (QH) searched for trials, assessed the quality of trials, extracted data, analysed data and dra ed the review. Bi Rong Dong (BD) advised and assisted in writing the protocol and the review, searched for trials and developed the review. Cochrane Library Trusted evidence. Informed decisions. Better health. Cochrane Database of Systematic Reviews Taixiang Wu (TW) contributed to the development of the methods of the review and assisted with data extraction and analysis. D E C L A R A T I O N S O F I N T E R E S T Qiukui Hao: none known. Bi Rong Dong: none known. Taixiang Wu: none known. S O U R C E S O F S U P P O R T Internal sources • Chinese Cochrane Center, West China Hospital of..
References
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H A R A C T E R I S T I C S O F S T U D I E S, with 2 parallel arms Method of randomisation: not clearly stated Blinding: double-blind
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