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@CovidAnalysis
All Studies   Meta Analysis    Recent:   

Phase 2 study of oral sabizabulin for the treatment of SARS-CoV-2 in hospitalized patients at high risk for ARDS

Gordon, M., 32nd European Congress of Clinical Microbiology & Infectious Diseases
Apr 2022  
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Mortality, ITT 82% Improvement Relative Risk Ventilation time 76% ICU time 73% Sabizabulin  Gordon et al.  LATE TREATMENT  DB RCT Is late treatment with antiandrogens beneficial for COVID-19? Double-blind RCT in the USA Lower mortality (p=0.042) and shorter ICU admission (p=0.026) c19early.org Gordon, M., 32nd European Congress of .., Apr 2022 Favorssabizabulin Favorscontrol 0 0.5 1 1.5 2+
7th treatment shown to reduce risk in September 2020
 
*, now with p = 0.000000056 from 49 studies.
Lower risk for mortality, ventilation, ICU admission, hospitalization, recovery, cases, and viral clearance.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,500+ studies for 81 treatments. c19early.org
Phase 2 RCT of sabizabulin showing lower mortality with treatment. For more discussion see1.
Important missing comments or errors? Let us know.
risk of death, 82.0% lower, RR 0.18, p = 0.04, ITT.
ventilation time, 76.5% lower, relative time 0.24, p = 0.14.
ICU time, 72.9% lower, relative time 0.27, p = 0.03.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Gordon et al., 25 Apr 2022, Double Blind Randomized Controlled Trial, placebo-controlled, USA, peer-reviewed, 1 author.
This PaperAntiandrogensAll
Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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