The association between vitamin D intake with inflammatory and biochemical indices and mortality in critically ill patients with COVID‐19: A case‐control study
Maryam Gholamalizadeh, Faezeh Rabbani, Mina Ahmadzadeh, Azadeh Hajipour, Hayehe Musavi, Khadijeh Abbasi Mobarakeh, Zahra Salimi, Bojlul Bahar, Zahra Mahmoodi, Somayeh Gholami, Samaneh Mirzaei Dahka, Saeid Doaei, Mokammad Esmail Akbari
Immunity, Inflammation and Disease, doi:10.1002/iid3.844
Background: The coronavirus disease-2019 (COVID-19) has become a worldwide health issue with widespread hospitalization and dependence on the intensive care unit (ICU). Vitamin D has a key role in modulating immune cells and modulating the inflammatory responses. This study aimed to investigate the association of vitamin D supplementation with inflammatory, biochemical, and mortality indices in critically ill patients with COVID-19. Methods: This case-control study was conducted on critically ill COVID-19 patients hospitalized in the ICU including the survived >30 day patients as the case group and dead patients as the control group. The status of vitamin D
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest.
ETHICS STATEMENT This study was approved by the Institutional Review Board at Shahid-Beheshti University of Medical Sciences (code: IR.SBMU.CRC.REC.1399.031). All patients signed an informed consent form at baseline. Institutional consent forms were used in this study.
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