Evaluation of the recovery rate and prevention of hospitalization among covid-19 outpatients: a randomized clinical trial comparing N-acetylcysteine with Bromhexine

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First, PCR-confirmed ' 'COVID-19 patients were divided into tree groups, one of these groups received ' 'N-acetylcysteine while the other received bromhexine and One of these groups did not receive ' 'any medication. The patients were followed up on the seventh and fourteenth days of the ' 'disease in terms of the duration of changes in oxygen saturation and recovery. The ' 'hospitalization and death of the patients were also evaluated after one month.\n' 'Results: Out of 225 studied patients, oxygen saturation was increased by 1.33% in the third ' 'visit of the patients who received N-acetylcysteine compared to their first visit. This ' 'percentage was 1.19% in the patients who received bromhexine.29.77% of the patients were ' 'admitted to the hospital and 70.23% of them had no history of hospitalization within 14 day ' 'and their mortality rate was 9.33% in control group and it was zero in both groups of ' 'patients who received drug.\n' 'Conclusions: The results of this study showed that early initiation of Bromhexine and ' 'N-acetylcysteine can effectively reduce the hospitalization rate and mortality and shorten ' 'the duration of hospitalization.\n' 'Clinical trial code: IRCT20220302054167N1 and ethics code: IR.UMSHA.REC.1400.957</jats:p>', 'DOI': '10.21203/rs.3.rs-2309373/v2', 'type': 'posted-content', 'created': {'date-parts': [[2023, 4, 3]], 'date-time': '2023-04-03T19:54:07Z', 'timestamp': 1680551647000}, 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'Evaluation of the recovery rate and prevention of hospitalization among covid-19 outpatients: a ' 'randomized clinical trial comparing N-acetylcysteine with Bromhexine', 'prefix': '10.21203', 'author': [ { 'given': 'Anahita Eslami', 'family': 'Ghayour', 'sequence': 'first', 'affiliation': [{'name': 'Hamedan University of medical science'}]}, { 'given': 'Sasan', 'family': 'Nazari', 'sequence': 'additional', 'affiliation': [{'name': 'Hamedan University of medical science'}]}, { 'given': 'Fariba', 'family': 'Keramat', 'sequence': 'additional', 'affiliation': [{'name': 'Hamedan University of medical science'}]}, { 'given': 'Fatemeh', 'family': 'Shahbazi', 'sequence': 'additional', 'affiliation': [{'name': 'Hamedan University of medical science'}]}], 'member': '8761', 'reference': [ { 'issue': '5', 'key': 'ref1', 'doi-asserted-by': 'publisher', 'first-page': '668', 'DOI': '10.1038/s41564-020-0709-x', 'article-title': 'The new scope of virus taxonomy: partitioning the virosphere into 15 ' 'hierarchical ranks', 'volume': '5', 'author': 'International Committee on Taxonomy of Viruses Executive Committee', 'year': '2020', 'unstructured': 'International Committee on Taxonomy of Viruses Executive Committee. 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