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Effects of Ivermectin-azithromycin-cholecalciferol combined therapy on COVID-19 infected patients: A proof of concept study

Espitia-Hernandez et al., Biomedical Research, 31:5, Aug 2020
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https://c19early.org/espitiahernandezd.html
Recovery time 70% Improvement Relative Risk Viral+ at day 10 97% primary Vitamin D  Espitia-Hernandez et al.  EARLY TREATMENT Is early treatment with vitamin D + combined treatments beneficial for COVID-19? Retrospective 35 patients in Mexico Faster recovery (p=0.0001) and improved viral clearance (p<0.0001) c19early.org Espitia-Hernandez et al., Biomedical R.., Aug 2020 Favorsvitamin D Favorscontrol 0 0.5 1 1.5 2+
Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020, now with p < 0.00000000001 from 125 studies, recognized in 18 countries.
Lower risk for mortality, ICU, hospitalization, progression, recovery, cases, and viral clearance.
No treatment is 100% effective. Protocols combine treatments.
5,700+ studies for 169 treatments. c19early.org
Small study with 28 patients treated with ivermectin + AZ + cholecalciferol and 7 control patients.
All treated patients were PCR- at day 10 while all control patients remained PCR+. The mean duration of symptoms was 3 days in the treatment group and 10 days in the control group.
Important missing comments or errors? Let us know.
Study covers vitamin D and ivermectin.
recovery time, 70.0% lower, relative time 0.30, p < 0.001, treatment 28, control 7.
risk of viral+ at day 10, 97.2% lower, RR 0.03, p < 0.001, treatment 0 of 28 (0.0%), control 7 of 7 (100.0%), NNT 1.0, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm), primary outcome.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Espitia-Hernandez et al., 15 Aug 2020, retrospective, Mexico, peer-reviewed, 5 authors, dosage 8,000IU daily, 4000IU twice daily for 30 days, this trial uses multiple treatments in the treatment arm (combined with ivermectin and azithromycin) - results of individual treatments may vary.
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. IMA and WCH provide treatment protocols.
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