Revisiting vitamin D status and supplementation for in-patients with intellectual and developmental disability in the North of England, UK
Bethany Dudley, Marcin Ostrowski, Vlad Ciausu, Chris Ince, Dr Iain Mckinnon
BJPsych Bulletin, doi:10.1192/bjb.2021.55
Aims and method To re-evaluate vitamin D testing and supplementation among in-patients with intellectual and developmental disability (IDD) and examine any correlates with physical health conditions, including COVID-19. Records of all in-patients between January 2019 and July 2020 (n = 78) were examined for 25-hydroxyvitamin D (25(OH)D) level, ward area, supplementation status, test seasonality, medication and health status.
Results The mean 25(OH)D level for supplemented (800 IU/day) patients was 75 nmol/L (s.d. = 20), compared with 40 nmol/L (s.d. = 19) in the non-supplemented group (P < 0.001). Thirty-eight percent of those who were in-patients during the first wave of the COVID-19 pandemic developed symptoms, but the small sample size could not establish vitamin D levels as a predictor of outcome. Clinical implications Vitamin D (800 IU/day) supplementation is effective but the adequacy of the nationally recommended dose of 400 IU/day is unclear. Links to COVID-19 merit further research.
Authors' contributions B.D., M.O. and V.C. were involved in acquisition and analysis of data, drafting of the manuscript and approval of the final version. C.I. was involved in the design of the study, revision of the manuscript and approval of the final version. I.M. was involved in the design of the study, acquisition and analysis of data, drafting and revision of the manuscript, as well as final approval.
Declaration of interest None.
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