Exploration of shared gene signatures and molecular mechanisms between psoriasis and COVID-19: evidence from transcriptome data

DOI record: { "DOI": "10.1007/s00335-026-10194-8", "ISSN": [ "0938-8990", "1432-1777" ], "URL": "http://dx.doi.org/10.1007/s00335-026-10194-8", "alternative-id": [ "10194" ], "article-number": "23", "assertion": [ { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Received", "name": "received", "order": 1, "value": "19 August 2025" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "Accepted", "name": "accepted", "order": 2, "value": "3 January 2026" }, { "group": { "label": "Article History", "name": "ArticleHistory" }, "label": "First Online", "name": "first_online", "order": 3, "value": "13 January 2026" }, { "group": { "label": "Declarations", "name": "EthicsHeading" }, "name": "Ethics", "order": 1 }, { "group": { "label": "Conflict of interest", "name": "EthicsHeading" }, "name": "Ethics", "order": 2, "value": "The authors declare no competing interests." }, { "group": { "label": "Ethical approval", "name": "EthicsHeading" }, "name": "Ethics", "order": 3, "value": "Not applicable." }, { "group": { "label": "Consent to participate", "name": "EthicsHeading" }, "name": "Ethics", "order": 4, "value": "Not applicable." }, { "group": { "label": "Consent for publication", "name": "EthicsHeading" }, "name": "Ethics", "order": 5, "value": "Not applicable." } ], "author": [ { "affiliation": [], "family": "Dong", "given": "Rong-Jing", "sequence": "first" }, { "affiliation": [], "family": "Yang", "given": "Lu-Hui", "sequence": "additional" }, { "affiliation": [], "family": "Li", "given": "Yu-Ye", "sequence": "additional" }, { "affiliation": [], "family": "Lu", "given": "You-Wang", "sequence": "additional" } ], "container-title": "Mammalian Genome", "container-title-short": "Mamm Genome", "content-domain": { "crossmark-restriction": false, "domain": [ "link.springer.com" ] }, "created": { "date-parts": [ [ 2026, 1, 13 ] ], "date-time": "2026-01-13T21:12:29Z", "timestamp": 1768338749000 }, "deposited": { "date-parts": [ [ 2026, 1, 14 ] ], "date-time": "2026-01-14T09:05:38Z", "timestamp": 1768381538000 }, "funder": [ { "DOI": "10.13039/501100001809", "award": [ "82203934" ], "award-info": [ { "award-number": [ "82203934" ] } ], "doi-asserted-by": "crossref", "id": [ { "asserted-by": "crossref", "id": "10.13039/501100001809", "id-type": "DOI" } ], "name": "the National Natural Science Foundation of China" }, { "DOI": "10.13039/501100001809", "award": [ "82272356" ], "award-info": [ { "award-number": [ "82272356" ] } ], "doi-asserted-by": "crossref", "id": [ { "asserted-by": "crossref", "id": "10.13039/501100001809", "id-type": "DOI" } ], "name": "the National Natural Science Foundation of China" }, { "award": [ "21xjz33R" ], "award-info": [ { "award-number": [ "21xjz33R" ] } ], "name": "the Talent Introduction Project of Hubei Polytechnic University" }, { "award": [ "21xjz34R" ], "award-info": [ { "award-number": [ "21xjz34R" ] } ], "name": "the Talent Introduction Project of Hubei Polytechnic University" }, { "award": [ "202403AC100011" ], "award-info": [ { "award-number": [ "202403AC100011" ] } ], "name": "the Key research and development program of Yunnan Province" } ], "indexed": { "date-parts": [ [ 2026, 1, 14 ] ], "date-time": "2026-01-14T15:05:11Z", "timestamp": 1768403111024, "version": "3.49.0" }, "is-referenced-by-count": 0, "issue": "1", "issued": { "date-parts": [ [ 2026, 1, 13 ] ] }, "journal-issue": { "issue": "1", "published-print": { "date-parts": [ [ 2026, 12 ] ] } }, "language": "en", "license": [ { "URL": "https://creativecommons.org/licenses/by-nc-nd/4.0", "content-version": "tdm", "delay-in-days": 0, "start": { "date-parts": [ [ 2026, 1, 13 ] ], "date-time": "2026-01-13T00:00:00Z", "timestamp": 1768262400000 } }, { "URL": "https://creativecommons.org/licenses/by-nc-nd/4.0", "content-version": "vor", "delay-in-days": 0, "start": { "date-parts": [ [ 2026, 1, 13 ] ], "date-time": "2026-01-13T00:00:00Z", "timestamp": 1768262400000 } } ], "link": [ { "URL": "https://link.springer.com/content/pdf/10.1007/s00335-026-10194-8.pdf", "content-type": "application/pdf", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://link.springer.com/article/10.1007/s00335-026-10194-8", "content-type": "text/html", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://link.springer.com/content/pdf/10.1007/s00335-026-10194-8.pdf", "content-type": "application/pdf", "content-version": "vor", "intended-application": "similarity-checking" } ], "member": "297", "original-title": [], "prefix": "10.1007", "published": { "date-parts": [ [ 2026, 1, 13 ] ] }, "published-online": { "date-parts": [ [ 2026, 1, 13 ] ] }, "published-print": { "date-parts": [ [ 2026, 12 ] ] }, "publisher": "Springer Science and Business Media LLC", "reference": [ { "DOI": "10.1038/nmeth.4463", "author": "S Aibar", "doi-asserted-by": "publisher", "first-page": "1083", "issue": "11", "journal-title": "Nat Methods", "key": "10194_CR1", "unstructured": "Aibar S et al (2017) SCENIC: single-cell regulatory network inference and clustering. Nat Methods 14(11):1083–1086", "volume": "14", "year": "2017" }, { "DOI": "10.1111/dth.13434", "author": "P Amerio", "doi-asserted-by": "publisher", "first-page": "e13434", "issue": "4", "journal-title": "Dermatol Ther", "key": "10194_CR2", "unstructured": "Amerio P et al (2020) COVID-19 and psoriasis: should we fear for patients treated with biologics? Dermatol Ther 33(4):e13434", "volume": "33", "year": "2020" }, { "DOI": "10.1038/s41467-019-11152-6", "author": "KH Antunes", "doi-asserted-by": "publisher", "first-page": "3273", "issue": "1", "journal-title": "Nat Commun", "key": "10194_CR3", "unstructured": "Antunes KH et al (2019) Microbiota-derived acetate protects against respiratory syncytial virus infection through a GPR43-type 1 interferon response. Nat Commun 10(1):3273", "volume": "10", "year": "2019" }, { "DOI": "10.1186/ar2488", "author": "SP Ardoin", "doi-asserted-by": "publisher", "first-page": "218", "issue": "5", "journal-title": "Arthritis Res Ther", "key": "10194_CR4", "unstructured": "Ardoin SP, Pisetsky DS (2008) Developments in the scientific Understanding of lupus. Arthritis Res Ther 10(5):218", "volume": "10", "year": "2008" }, { "DOI": "10.1016/j.jaut.2017.03.008", "author": "K Chen", "doi-asserted-by": "publisher", "first-page": "1", "journal-title": "J Autoimmun", "key": "10194_CR5", "unstructured": "Chen K, Liu J, Cao X (2017) Regulation of type I interferon signaling in immunity and inflammation: a comprehensive review. J Autoimmun 83:1–11", "volume": "83", "year": "2017" }, { "DOI": "10.1111/jdv.17635", "author": "PR Criado", "doi-asserted-by": "publisher", "first-page": "e1", "issue": "1", "journal-title": "J Eur Acad Dermatol Venereol", "key": "10194_CR6", "unstructured": "Criado PR et al (2022) COVID-19 and skin diseases: results from a survey of 843 patients with atopic dermatitis, psoriasis, vitiligo and chronic urticaria. J Eur Acad Dermatol Venereol 36(1):e1–e3", "volume": "36", "year": "2022" }, { "DOI": "10.1038/s41577-021-00633-9", "author": "YJ Crow", "doi-asserted-by": "publisher", "first-page": "471", "issue": "8", "journal-title": "Nat Rev Immunol", "key": "10194_CR7", "unstructured": "Crow YJ, Stetson DB (2022) The type I interferonopathies: 10 years on. Nat Rev Immunol 22(8):471–483", "volume": "22", "year": "2022" }, { "DOI": "10.1038/jid.2014.532", "author": "AM D’Erme", "doi-asserted-by": "publisher", "first-page": "1025", "issue": "4", "journal-title": "J Invest Dermatol", "key": "10194_CR8", "unstructured": "D’Erme AM et al (2015) IL-36γ (IL-1F9) is a biomarker for psoriasis skin lesions. J Invest Dermatol 135(4):1025–1032", "volume": "135", "year": "2015" }, { "DOI": "10.3389/fimmu.2022.930866", "author": "Z Dong", "doi-asserted-by": "publisher", "first-page": "930866", "journal-title": "Front Immunol", "key": "10194_CR9", "unstructured": "Dong Z et al (2022) Identification of key molecules in COVID-19 patients significantly correlated with clinical outcomes by analyzing transcriptomic data. Front Immunol 13:930866", "volume": "13", "year": "2022" }, { "author": "G Dupire", "first-page": "CD011571", "issue": "3", "journal-title": "Cochrane Database Syst Rev", "key": "10194_CR10", "unstructured": "Dupire G et al (2019) Antistreptococcal interventions for guttate and chronic plaque psoriasis. Cochrane Database Syst Rev 3(3):CD011571", "volume": "3", "year": "2019" }, { "DOI": "10.1080/09546634.2020.1789051", "author": "A Ebrahimi", "doi-asserted-by": "publisher", "first-page": "699", "issue": "2", "journal-title": "J Dermatolog Treat", "key": "10194_CR11", "unstructured": "Ebrahimi A, Sayad B, Rahimi Z (2022) COVID-19 and psoriasis: biologic treatment and challenges. J Dermatolog Treat 33(2):699–703", "volume": "33", "year": "2022" }, { "DOI": "10.1038/s41584-020-0448-7", "author": "C Galeotti", "doi-asserted-by": "publisher", "first-page": "413", "issue": "8", "journal-title": "Nat Rev Rheumatol", "key": "10194_CR12", "unstructured": "Galeotti C, Bayry J (2020) Autoimmune and inflammatory diseases following COVID-19. Nat Rev Rheumatol 16(8):413–414", "volume": "16", "year": "2020" }, { "DOI": "10.1038/s41419-021-03724-6", "author": "Y Gao", "doi-asserted-by": "publisher", "first-page": "450", "issue": "5", "journal-title": "Cell Death Dis", "key": "10194_CR13", "unstructured": "Gao Y et al (2021) Single cell transcriptional zonation of human psoriasis skin identifies an alternative immunoregulatory axis conducted by skin resident cells. Cell Death Dis 12(5):450", "volume": "12", "year": "2021" }, { "DOI": "10.1016/S0140-6736(07)61128-3", "author": "CE Griffiths", "doi-asserted-by": "publisher", "first-page": "263", "issue": "9583", "journal-title": "Lancet", "key": "10194_CR14", "unstructured": "Griffiths CE, Barker JN (2007) Pathogenesis and clinical features of psoriasis. Lancet 370(9583):263–271", "volume": "370", "year": "2007" }, { "DOI": "10.1016/S0140-6736(20)32549-6", "author": "CEM Griffiths", "doi-asserted-by": "publisher", "first-page": "1301", "issue": "10281", "journal-title": "Lancet", "key": "10194_CR15", "unstructured": "Griffiths CEM et al (2021) Psoriasis. Lancet 397(10281):1301–1315", "volume": "397", "year": "2021" }, { "DOI": "10.1155/2015/258430", "author": "AT Gunes", "doi-asserted-by": "publisher", "first-page": "258430", "journal-title": "J Immunol Res", "key": "10194_CR16", "unstructured": "Gunes AT et al (2015) Possible triggering effect of influenza vaccination on psoriasis. J Immunol Res 2015:258430", "volume": "2015", "year": "2015" }, { "DOI": "10.1038/nrrheum.2009.237", "author": "JC Hall", "doi-asserted-by": "publisher", "first-page": "40", "issue": "1", "journal-title": "Nat Rev Rheumatol", "key": "10194_CR17", "unstructured": "Hall JC, Rosen A (2010) Type i interferons: crucial participants in disease amplification in autoimmunity. Nat Rev Rheumatol 6(1):40–49", "volume": "6", "year": "2010" }, { "DOI": "10.3390/v12060672", "author": "W Hao", "doi-asserted-by": "publisher", "journal-title": "Viruses", "key": "10194_CR18", "unstructured": "Hao W, Wang L, Li S (2020) FKBP5 regulates RIG-I-mediated NF-kappaB activation and influenza A virus infection. Viruses. https://doi.org/10.3390/v12060672", "year": "2020" }, { "author": "RW Hu", "first-page": "6411", "issue": "20", "journal-title": "Eur Rev Med Pharmacol Sci", "key": "10194_CR19", "unstructured": "Hu RW et al (2021) Identification of hub genes and molecular subtypes in COVID-19 based on WGCNA. Eur Rev Med Pharmacol Sci 25(20):6411–6424", "volume": "25", "year": "2021" }, { "DOI": "10.1016/S0140-6736(20)30183-5", "author": "C Huang", "doi-asserted-by": "publisher", "first-page": "497", "issue": "10223", "journal-title": "Lancet", "key": "10194_CR20", "unstructured": "Huang C et al (2020) Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395(10223):497–506", "volume": "395", "year": "2020" }, { "DOI": "10.1186/ar2881", "author": "GD Kalliolias", "doi-asserted-by": "publisher", "first-page": "S1", "issue": "1", "journal-title": "Arthritis Res Ther", "key": "10194_CR21", "unstructured": "Kalliolias GD, Ivashkiv LB (2010) Overview of the biology of type I interferons. Arthritis Res Ther 12(1):S1", "volume": "12", "year": "2010" }, { "DOI": "10.1016/j.jid.2016.04.032", "author": "J Kim", "doi-asserted-by": "publisher", "first-page": "2173", "issue": "11", "journal-title": "J Invest Dermatol", "key": "10194_CR22", "unstructured": "Kim J et al (2016) The spectrum of mild to severe psoriasis vulgaris is defined by a common activation of IL-17 pathway genes, but with key differences in immune regulatory genes. J Invest Dermatol 136(11):2173–2182", "volume": "136", "year": "2016" }, { "author": "PK Krajewski", "first-page": "e632", "issue": "10", "journal-title": "J Eur Acad Dermatol Venereol", "key": "10194_CR23", "unstructured": "Krajewski PK, Matusiak L, Szepietowski JC (2021) Psoriasis flare-up associated with second dose of Pfizer-BioNTech BNT16B2b2 COVID-19 mRNA vaccine. J Eur Acad Dermatol Venereol 35(10):e632–e634", "volume": "35", "year": "2021" }, { "DOI": "10.1016/j.jaad.2020.05.018", "author": "Y Kuang", "doi-asserted-by": "publisher", "first-page": "670", "issue": "2", "journal-title": "J Am Acad Dermatol", "key": "10194_CR24", "unstructured": "Kuang Y et al (2020) Association of outdoor activity restriction and income loss with patient-reported outcomes of psoriasis during the COVID-19 pandemic: A web-based survey. J Am Acad Dermatol 83(2):670–672", "volume": "83", "year": "2020" }, { "DOI": "10.1111/dth.13509", "author": "Ö Kutlu", "doi-asserted-by": "publisher", "issue": "4", "journal-title": "Dermatol Ther", "key": "10194_CR25", "unstructured": "Kutlu Ö, Metin A (2020) Dermatological diseases presented before COVID-19: are patients with psoriasis and superficial fungal infections more vulnerable to the COVID-19? Dermatol Ther 33(4):e13509", "volume": "33", "year": "2020" }, { "DOI": "10.1038/jid.2014.28", "author": "B Li", "doi-asserted-by": "publisher", "first-page": "1828", "issue": "7", "journal-title": "J Invest Dermatol", "key": "10194_CR26", "unstructured": "Li B et al (2014) Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms. J Invest Dermatol 134(7):1828–1838", "volume": "134", "year": "2014" }, { "DOI": "10.1371/journal.pbio.3000849", "author": "NAP Lieberman", "doi-asserted-by": "publisher", "first-page": "e3000849", "issue": "9", "journal-title": "PLoS Biol", "key": "10194_CR27", "unstructured": "Lieberman NAP et al (2020) In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age. PLoS Biol 18(9):e3000849", "volume": "18", "year": "2020" }, { "DOI": "10.1097/BOR.0000000000000776", "author": "Y Liu", "doi-asserted-by": "publisher", "first-page": "155", "issue": "2", "journal-title": "Curr Opin Rheumatol", "key": "10194_CR28", "unstructured": "Liu Y, Sawalha AH, Lu Q (2021) COVID-19 and autoimmune diseases. Curr Opin Rheumatol 33(2):155–162", "volume": "33", "year": "2021" }, { "DOI": "10.3389/fimmu.2022.971071", "author": "YW Lu", "doi-asserted-by": "publisher", "first-page": "971071", "journal-title": "Front Immunol", "key": "10194_CR29", "unstructured": "Lu YW et al (2022) L36G is associated with cutaneous antiviral competence in psoriasis. Front Immunol 13:971071", "volume": "13", "year": "2022" }, { "DOI": "10.3109/15569527.2012.727936", "author": "VC Macias", "doi-asserted-by": "publisher", "first-page": "164", "issue": "2", "journal-title": "Cutan Ocul Toxicol", "key": "10194_CR30", "unstructured": "Macias VC, Cunha D (2013) Psoriasis triggered by tetanus-diphtheria vaccination. Cutan Ocul Toxicol 32(2):164–165", "volume": "32", "year": "2013" }, { "DOI": "10.1016/j.molcel.2021.04.008", "author": "L Martin-Sancho", "doi-asserted-by": "publisher", "first-page": "2656", "issue": "12", "journal-title": "Mol Cell", "key": "10194_CR31", "unstructured": "Martin-Sancho L et al (2021) Functional landscape of SARS-CoV-2 cellular restriction. Mol Cell 81(12):2656–2668e8", "volume": "81", "year": "2021" }, { "DOI": "10.1016/j.jdermsci.2017.11.010", "author": "JL Melero", "doi-asserted-by": "publisher", "first-page": "120", "issue": "2", "journal-title": "J Dermatol Sci", "key": "10194_CR32", "unstructured": "Melero JL et al (2018) Deciphering psoriasis. A bioinformatic approach. J Dermatol Sci 89(2):120–126", "volume": "89", "year": "2018" }, { "DOI": "10.1111/jocd.14508", "author": "R Miladi", "doi-asserted-by": "publisher", "first-page": "3364", "issue": "11", "journal-title": "J Cosmet Dermatol", "key": "10194_CR33", "unstructured": "Miladi R et al (2021) Pustular psoriasis flare-up in a patient with COVID-19. J Cosmet Dermatol 20(11):3364–3368", "volume": "20", "year": "2021" }, { "DOI": "10.1080/09546634.2020.1764904", "author": "S Nasiri", "doi-asserted-by": "publisher", "first-page": "448", "issue": "5", "journal-title": "J Dermatolog Treat", "key": "10194_CR34", "unstructured": "Nasiri S et al (2020) A challenging case of psoriasis flare-up after COVID-19 infection. J Dermatolog Treat 31(5):448–449", "volume": "31", "year": "2020" }, { "DOI": "10.1038/s41590-020-0743-0", "author": "D Nehar-Belaid", "doi-asserted-by": "publisher", "first-page": "1094", "issue": "9", "journal-title": "Nat Immunol", "key": "10194_CR35", "unstructured": "Nehar-Belaid D et al (2020) Mapping systemic lupus erythematosus heterogeneity at the single-cell level. Nat Immunol 21(9):1094–1106", "volume": "21", "year": "2020" }, { "DOI": "10.1016/j.cels.2020.10.003", "author": "KA Overmyer", "doi-asserted-by": "publisher", "first-page": "23", "issue": "1", "journal-title": "Cell Syst", "key": "10194_CR36", "unstructured": "Overmyer KA et al (2021) Large-Scale Multi-omic analysis of COVID-19 severity. Cell Syst 12(1):23–40e7", "volume": "12", "year": "2021" }, { "DOI": "10.1111/dth.13632", "author": "R Ozaras", "doi-asserted-by": "publisher", "first-page": "e13632", "issue": "4", "journal-title": "Dermatol Ther", "key": "10194_CR37", "unstructured": "Ozaras R et al (2020) Covid-19 and exacerbation of psoriasis. Dermatol Ther 33(4):e13632", "volume": "33", "year": "2020" }, { "DOI": "10.1128/JVI.02167-20", "author": "MB Phillips", "doi-asserted-by": "publisher", "journal-title": "J Virol", "key": "10194_CR38", "unstructured": "Phillips MB et al (2021) Lymphatic type 1 interferon responses are critical for control of systemic reovirus dissemination. J Virol. https://doi.org/10.1128/JVI.02167-20", "year": "2021" }, { "DOI": "10.1016/j.autrev.2017.07.001", "author": "C Picard", "doi-asserted-by": "publisher", "first-page": "897", "issue": "9", "journal-title": "Autoimmun Rev", "key": "10194_CR39", "unstructured": "Picard C, Belot A (2017) Does type-I interferon drive systemic autoimmunity? Autoimmun Rev 16(9):897–902", "volume": "16", "year": "2017" }, { "DOI": "10.1111/jdv.13091", "author": "RA Raposo", "doi-asserted-by": "publisher", "first-page": "1951", "issue": "10", "journal-title": "J Eur Acad Dermatol Venereol", "key": "10194_CR40", "unstructured": "Raposo RA et al (2015) Antiviral gene expression in psoriasis. J Eur Acad Dermatol Venereol 29(10):1951–1957", "volume": "29", "year": "2015" }, { "DOI": "10.18637/jss.v079.c02", "author": "MC Sachs", "doi-asserted-by": "publisher", "journal-title": "J Stat Softw", "key": "10194_CR41", "unstructured": "Sachs MC (2017) plotROC: a tool for plotting ROC curves. J Stat Softw. https://doi.org/10.18637/jss.v079.c02", "year": "2017" }, { "DOI": "10.1146/annurev-virology-092818-015756", "author": "JW Schoggins", "doi-asserted-by": "publisher", "first-page": "567", "issue": "1", "journal-title": "Annu Rev Virol", "key": "10194_CR42", "unstructured": "Schoggins JW (2019) Interferon-stimulated genes: what do they all do? Annu Rev Virol 6(1):567–584", "volume": "6", "year": "2019" }, { "DOI": "10.1016/j.jtos.2021.09.007", "author": "S Singh", "doi-asserted-by": "publisher", "first-page": "184", "journal-title": "Ocul Surf", "key": "10194_CR43", "unstructured": "Singh S et al (2022) SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response. Ocul Surf 23:184–194", "volume": "23", "year": "2022" }, { "DOI": "10.1016/j.cyto.2018.12.018", "author": "B Skaug", "doi-asserted-by": "publisher", "first-page": "154635", "journal-title": "Cytokine", "key": "10194_CR44", "unstructured": "Skaug B, Assassi S (2020) Type I interferon dysregulation in systemic sclerosis. Cytokine 132:154635", "volume": "132", "year": "2020" }, { "DOI": "10.1111/jdv.17582", "author": "E Sotiriou", "doi-asserted-by": "publisher", "first-page": "e857", "issue": "12", "journal-title": "J Eur Acad Dermatol Venereol", "key": "10194_CR45", "unstructured": "Sotiriou E et al (2021) Psoriasis exacerbation after COVID-19 vaccination: a report of 14 cases from a single centre. J Eur Acad Dermatol Venereol 35(12):e857–e859", "volume": "35", "year": "2021" }, { "DOI": "10.1186/s13054-020-03158-0", "author": "A Stallmach", "doi-asserted-by": "publisher", "first-page": "444", "issue": "1", "journal-title": "Crit Care", "key": "10194_CR46", "unstructured": "Stallmach A et al (2020) Infliximab against severe COVID-19-induced cytokine storm syndrome with organ failure-a cautionary case series. Crit Care 24(1):444", "volume": "24", "year": "2020" }, { "DOI": "10.1016/j.jid.2018.01.039", "author": "J Takeshita", "doi-asserted-by": "publisher", "first-page": "1726", "issue": "8", "journal-title": "J Invest Dermatol", "key": "10194_CR47", "unstructured": "Takeshita J et al (2018) Risk of serious Infection, opportunistic Infection, and herpes Zoster among patients with psoriasis in the united Kingdom. J Invest Dermatol 138(8):1726–1735", "volume": "138", "year": "2018" }, { "DOI": "10.1016/j.jid.2018.12.018", "author": "LC Tsoi", "doi-asserted-by": "publisher", "first-page": "1480", "issue": "7", "journal-title": "J Invest Dermatol", "key": "10194_CR48", "unstructured": "Tsoi LC et al (2019) Atopic dermatitis is an IL-13-Dominant disease with greater molecular heterogeneity compared to psoriasis. J Invest Dermatol 139(7):1480–1489", "volume": "139", "year": "2019" }, { "DOI": "10.1186/s13075-017-1501-z", "author": "MJ Wahadat", "doi-asserted-by": "publisher", "first-page": "4", "issue": "1", "journal-title": "Arthritis Res Ther", "key": "10194_CR49", "unstructured": "Wahadat MJ et al (2018) Type I IFN signature in childhood-onset systemic lupus erythematosus: a conspiracy of DNA- and RNA-sensing receptors? Arthritis Res Ther 20(1):4", "volume": "20", "year": "2018" }, { "DOI": "10.1126/scitranslmed.3006245", "author": "K Wolk", "doi-asserted-by": "publisher", "first-page": "204ra129", "issue": "204", "journal-title": "Sci Transl Med", "key": "10194_CR50", "unstructured": "Wolk K et al (2013) IL-29 is produced by T(H)17 cells and mediates the cutaneous antiviral competence in psoriasis. Sci Transl Med 5(204):204ra129", "volume": "5", "year": "2013" }, { "key": "10194_CR51", "unstructured": "Worldometer (2022) Covid-19 coronavirus pandemic. https://www.worldometers.info/coronavirus/#countries" }, { "DOI": "10.1016/j.jmii.2020.03.005", "author": "D Wu", "doi-asserted-by": "publisher", "first-page": "368", "issue": "3", "journal-title": "J Microbiol Immunol Infect", "key": "10194_CR52", "unstructured": "Wu D, Yang XO (2020) TH17 responses in cytokine storm of COVID-19: an emerging target of JAK2 inhibitor fedratinib. J Microbiol Immunol Infect 53(3):368–370", "volume": "53", "year": "2020" }, { "DOI": "10.1007/s40257-022-00721-z", "author": "PC Wu", "doi-asserted-by": "publisher", "first-page": "775", "issue": "6", "journal-title": "Am J Clin Dermatol", "key": "10194_CR53", "unstructured": "Wu PC et al (2022) New onset and exacerbations of psoriasis following COVID-19 vaccines: a systematic review. Am J Clin Dermatol 23(6):775–799", "volume": "23", "year": "2022" }, { "DOI": "10.1007/s13671-017-0178-5", "author": "D Yan", "doi-asserted-by": "publisher", "first-page": "94", "issue": "2", "journal-title": "Curr Dermatol Rep", "key": "10194_CR54", "unstructured": "Yan D et al (2017) The role of the skin and gut Microbiome in psoriatic disease. Curr Dermatol Rep 6(2):94–103", "volume": "6", "year": "2017" }, { "author": "YJ Zhang", "first-page": "225", "issue": "1", "journal-title": "Mol Med Rep", "key": "10194_CR55", "unstructured": "Zhang YJ et al (2019) Integrated bioinformatic analysis of differentially expressed genes and signaling pathways in plaque psoriasis. Mol Med Rep 20(1):225–235", "volume": "20", "year": "2019" }, { "DOI": "10.3389/fimmu.2021.733171", "author": "C Zhang", "doi-asserted-by": "publisher", "first-page": "733171", "journal-title": "Front Immunol", "key": "10194_CR56", "unstructured": "Zhang C et al (2021) Transcriptional profiling and machine learning unveil a concordant biosignature of type I Interferon-Inducible host response across nasal swab and pulmonary tissue for COVID-19 diagnosis. Front Immunol 12:733171", "volume": "12", "year": "2021" }, { "DOI": "10.3390/ijms23136955", "author": "S Zhou", "doi-asserted-by": "publisher", "journal-title": "Int J Mol Sci", "key": "10194_CR57", "unstructured": "Zhou S, Yao Z (2022) Roles of infection in psoriasis. Int J Mol Sci. https://doi.org/10.3390/ijms23136955", "year": "2022" }, { "DOI": "10.1016/j.chom.2020.04.017", "author": "Z Zhou", "doi-asserted-by": "publisher", "first-page": "883", "issue": "6", "journal-title": "Cell Host Microbe", "key": "10194_CR58", "unstructured": "Zhou Z et al (2020) Heightened innate immune responses in the respiratory tract of COVID-19 patients. Cell Host Microbe 27(6):883–890e2", "volume": "27", "year": "2020" }, { "DOI": "10.1016/S0140-6736(20)30305-6", "author": "A Zumla", "doi-asserted-by": "publisher", "first-page": "e35", "issue": "10224", "journal-title": "Lancet", "key": "10194_CR59", "unstructured": "Zumla A et al (2020) Reducing mortality from 2019-nCoV: host-directed therapies should be an option. Lancet 395(10224):e35–e36", "volume": "395", "year": "2020" } ], "reference-count": 59, "references-count": 59, "relation": {}, "resource": { "primary": { "URL": "https://link.springer.com/10.1007/s00335-026-10194-8" } }, "score": 1, "short-title": [], "source": "Crossref", "subject": [], "subtitle": [], "title": "Exploration of shared gene signatures and molecular mechanisms between psoriasis and COVID-19: evidence from transcriptome data", "type": "journal-article", "update-policy": "https://doi.org/10.1007/springer_crossmark_policy", "volume": "37" }