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Selenium and mercury concentrations in biological samples from patients with COVID-19

Chanihoon et al., Journal of Trace Elements in Medicine and Biology, doi:10.1016/j.jtemb.2022.127038
Sep 2022  
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Analysis of 115 COVID-19 patients and 158 healthy controls, showing lower selenium levels and higher mercury levels in all sample types for COVID-19 patients (scalp hair, blood, serum, sputum, saliva, nasal fluid).
Chanihoon et al., 30 Sep 2022, prospective, Pakistan, peer-reviewed, 10 authors, study period October 2021 - January 2022.
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Selenium and mercury concentrations in biological samples from patients with COVID-19
Ghulam Qadir Chanihoon, Hassan Imran Afridi, Ahsanullah Unar, Farah Naz Talpur, Hadi Bakhsh Kalochi, Rayan Nassani, Nazia Laghari, Najam Uddin, Ali Ghulam, Anees Ur Rahman Chandio
Journal of Trace Elements in Medicine and Biology, doi:10.1016/j.jtemb.2022.127038
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre -including this research content -immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Akhtar, Das, Ismail, Wahid, Saeed et al., Nutritional perspectives for the prevention and mitigation of COVID-19, Nutr. Rev
Alghasham, Of, Association of blood lead level with elevated blood pressure in hypertensive patients, Ncbi.Nlm.Nih.Gov
Ali, Mitigative role of garlic and vitamin E against cytotoxic, genotoxic, and apoptotic effects of lead acetate and mercury chloride on WI-38 cells, Pharmacol. Rep
Beck, Levander, Handy, Selenium deficiency and viral infection, J. Nutr
Beck, Matthews, Micronutrients and host resistance to viral infection, Proc. Nutr. Soc
Bermano, Méplan, Mercer, Hesketh, Selenium and viral infection: are there lessons for COVID-19?, Br. J. Nutr
Brzoska, Moniuszko-Jakoniuk, Jurczuk, Chraniuk, The influence of cadmium on bone tissue in rats, Pol. J. Environ. Stud
Cascella, Rajnik, Aleem, Dulebohn, Di Napoli, Features, evaluation, and treatment of coronavirus (COVID-19)
Chelkeba, Ahmadi, Abdollahi, Najafi, Ghadimi et al., The effect of parenteral selenium on outcomes of mechanically ventilated patients following sepsis: a prospective randomized clinical trial, Ann. Intensive Care
Chiba, Masironi, Toxic and trace elements in tobacco and tobacco smoke, Bull. World Health Organ
Csalari, Szantai, Transfer rate of cadmium, lead, zinc and iron from the tobacco-cut of the most popular Hungarian cigarette brands to the combustion products, Acta Aliment
Dlouha, Sevcikova, Dokoupilova, Zita, Heindl et al., Effect of dietary selenium sources on growth performance, breast muscle selenium, glutathione peroxidase activity and oxidative stability in broilers, Czech J. Anim. Sci
Emeny, Korrick, Li, Nadeau, Prenatal exposure to mercury in relation to infant infections and respiratory symptoms in the New Hampshire Birth Cohort Study
Fairweather-Tait, Bao, Broadley, Collings, Ford et al., Selenium in human health and disease
Fairweather-Tait, Bao, Broadley, Collings, Ford et al., Selenium in human health and disease, Liebertpub.Com, doi:10.1089/ars.2010.3275
Fakhrolmobasheri, Nasr-Esfahany, Khanahmad, Zeinalian, Selenium supplementation can relieve the clinical complications of COVID-19 and other similar viral infections, Int J. Vitam. Nutr. Res
Forceville, Effects of high doses of selenium, as sodium selenite, in septic shock patients a placebo-controlled, randomized, double-blind, multi-center phase II study-selenium and sepsis, J. Trace Elem. Med. Biol
Gardner, Nyland, Evans, Wang, Doyle et al., Mercury induces an unopposed inflammatory response in human peripheral blood mononuclear cells in vitro, Environ. Health Perspect
Gasmi, Tippairote, Mujawdiya, Peana, Menzel et al., Micronutrients as immunomodulatory tools for COVID-19 management, Clin. Immunol
Gladyshev, Arnér, Berry, Brigelius-Flohé, Bruford et al., Selenoprotein gene nomenclature, J. Biol. Chem, doi:10.1074/JBC.M116.756155
Gordon, Jang, Bouhaddou, Xu, Obernier et al., A SARS-CoV-2 protein interaction map reveals targets for drug repurposing, Nature
Gröber, Holick, The coronavirus disease (COVID-19) -a supportive approach with selected micronutrients, J. Int. De. Vitaminol. Et. De. Nutr, doi:10.1024/0300-9831/A000693
Guillin, Vindry, Ohlmann, Chavatte, Selenium, selenoproteins and viral infection
Guillin, Vindry, Ohlmann, Chavatte, Selenium, selenoproteins and viral infection
Guillin, Vindry, Ohlmann, Chavatte, Selenium, selenoproteins and viral infection, doi:10.3390/NU11092101
Han, Castranova, Comparative cytotoxicity of cadmium and mercury in a human bronchial epithelial cell line (BEAS-2B) and its role in oxidative stress and induction of heat shock, doi:10.1080/15287390701212695
Harthill, Micronutrient selenium deficiency influences evolution of some viral infectious diseases, Biol. Trace Elem. Res
He, Xun, Liu, Morris, Reis et al., Mercury exposure in young adulthood and incidence of diabetes later in life: the CARDIA Trace Element Study, Am. Diabetes Assoc, doi:10.2337/dc12-1842
Hecht, Tobacco carcinogens, their biomarkers and tobacco-induced cancer, Nat. Rev. Cancer
Heinrich, Guo, Trepka, Brief report: low-level mercury exposure and risk of asthma in school-age children, Epidemiology
Hiffler, Rakotoambinina, Selenium and RNA Virus Interactions: Potential Implications for SARS-CoV-2 Infection (COVID-19), Front. Nutr, doi:10.3389/FNUT.2020.00164/BIBTEX
Houston, Role of mercury toxicity in hypertension, cardiovascular disease, and stroke, J. Clin. Hypertens. (Greenwich), doi:10.1111/J.1751-7176.2011.00489.X
Hu, Singh, Chan, Mercury exposure, blood pressure, and hypertension: a systematic review and dose-response meta-analysis, Environ. Health Perspect, doi:10.1289/EHP2863
Husgafvel-Pursiainen, Genotoxicity of environmental tobacco smoke: a review, Mutat. Res./Rev. Mutat. Res
Im, Je, Baek, Chung, Kwon et al., Nutritional status of patients with COVID-19, Int. J. Infect. Dis, doi:10.1016/j.ijid.2020.08.018
Jagannathan, Jose, Identification of a unique gene expression signature in mercury and 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin coexposed cells, Academic.Oup.Com
Jaishankar, Tseten, Anbalagan, Mathew, Beeregowda, Toxicity, mechanism and health effects of some heavy metals, Interdiscip. Toxicol, doi:10.2478/INTOX-2014-0009
Jhu, Coronavirus 2019-nCoV global cases by Johns Hopkins CSSE
Kazi, Jalbani, Kazi, Jamali, Arain et al., Evaluation of toxic metals in blood and urine samples of chronic renal failure patients, before and after dialysis, Ren. Fail
Kazi, Memon, Afridi, Jamali, Arain et al., Determination of cadmium in whole blood and scalp hair samples of Pakistani male lung cancer patients by electrothermal atomic absorption spectrometer, Sci. Total Environ
Kieliszek, Lipinski, Selenium supplementation in the prevention of coronavirus infections (COVID-19, Med Hypotheses, doi:10.1016/J.MEHY.2020.109878
Kobal, Horvat, Prezelj, Briški, Krsnik et al., The impact of long-term past exposure to elemental mercury on antioxidative capacity and lipid peroxidation in mercury miners, J. Trace Elem. Med. Biol
Kolachi, Kazi, Afridi, Kazi, Khan et al., Status of toxic metals in biological samples of diabetic mothers and their neonates, Biol. Trace Elem. Res, doi:10.1007/S12011-010-8879-7
Li, Li, Yamate, Li, Ikuta, Lipid rafts play an important role in the early stage of severe acute respiratory syndrome-coronavirus life cycle, Microbes Infect
Liu, Lei, Waalkes, Beliles, Morgan, Genomic analysis of the rat lung following elemental mercury vapor exposure, Toxicol. Sci
Long, Liu, Zhou, He, Dietary serine supplementation regulates selenoprotein transcription and selenoenzyme activity in pigs, Biol. Trace Elem. Res
Lubick, Immunity: mercury alters immune system response in artisanal gold miners
Mahmoodpoor, Hamishehkar, Sanaie, Behruzizad, Iranpour et al., Antioxidant reserve of the lungs and ventilator-associated pneumonia: a clinical trial of high dose selenium in critically ill patients, J. Crit. Care
Manzanares, Biestro, Torre, Galusso, Facchin et al., High-dose selenium reduces ventilator-associated pneumonia and illness severity in critically ill patients with systemic inflammation, Intensive Care Med
Mehdi, Hornick, Istasse, Dufrasne, Selenium in the environment, metabolism and involvement in body functions, Molecules
Min, Min, Association between total blood mercury and exhaled nitric oxide in US adults, Nitric Oxide
Moghaddam, Heller, Sun, Seelig, Cherkezov et al., Selenium deficiency is associated with mortality risk from COVID-19, Nutrients
Moghaddam, Heller, Sun, Seelig, Cherkezov et al., Selenium deficiency is associated with mortality risk from COVID-19, Nutrients
Molecules, Selenium-fascinating microelement, properties and sources in food, doi:10.3390/molecules24071298
Mulchi, Adamu, Bell, Chaney, Residual heavy metal concentrations in sludge amended coastal plain soils-II. Predicting metal concentrations in tobacco from soil test information, Commun. Soil Sci. Plant Anal
Murthy, Gomersall, Fowler, Care for critically ill patients with COVID-19, JAMA
Park, Park, Induction of reactive oxygen species and apoptosis in BEAS-2B cells by mercuric chloride, Toxicol. Vitr
Pateda, Sakakibara, Sera, Lung function assessment as an early biomonitor of mercury-induced health disorders in artisanal and small-scale gold mining areas in Indonesia, Int. J. Environ. Res. Public Health
Pearson, Clarke, Abbott, Knight, Cyranoski, SARS: what have we learned?, Nature
Razi, Akin, Harmanci, Akin, Renda, Serum heavy metal and antioxidant element levels of children with recurrent wheezing, Allergol. Immunopathol. (Madr.)
Reilly, Metal Contamination of Food: its Significance for Food Quality and Human Health
Richter, Bishop, Wang, Swahn, Tobacco smoke exposure and levels of urinary metals in the US youth and adult population: the National Health and Nutrition Examination Survey (NHANES) 1999-2004, Int J. Environ. Res Public Health
Sandstead, Penland, Alcock, Dayal, Chen et al., Effects of repletion with zinc and other micronutrients on neuropsychologic performance and growth of Chinese children, Am. J. Clin. Nutr
Shereen, Khan, Kazmi, Bashir, Siddique, COVID-19 infection: emergence, transmission, and characteristics of human coronaviruses, J. Adv. Res
Silva, Nyland, Gorman, Perisse, Ventura et al., Mercury exposure, malaria, and serum antinuclear/antinucleolar antibodies in Amazon populations in Brazil: a cross-sectional study, Environ. Health
Smiechowicz, Skoczynska, Nieckula-Szwarc, Kulpa, Kübler, Occupational mercury vapour poisoning with a respiratory failure, pneumomediastinum and severe quadriparesis, SAGE Open Med. Case Rep
Steinbrenner, Al-Quraishy, Dkhil, Wunderlich, Sies, Dietary selenium in adjuvant therapy of viral and bacterial infections, Adv. Nutr
Stohs, Bagchi, Oxidative mechanisms in the toxicity of metal ions, Free Radic, Biol. Med
Sørensen, Murata, Budtz-Jørgensen, Weihe, Grandjean, Prenatal methylmercury exposure as a cardiovascular risk factor at seven years of age, Epidemiology
Taborda, Blanquiceth, Urcuqui-Inchima, Latz, Hernandez, Highdensity lipoproteins decrease proinflammatory activity and modulate the innate immune response, J. Interferon Cytokine Res
Tsai, Kuo, Pan, Wu, Lin et al., Type 2 diabetes occurrence and mercury exposure -from the National Nutrition and Health Survey in Taiwan, Environ. Int, doi:10.1016/J.ENVINT.2019.02.038
Viezeliene, Beekhof, Gremmer, Rodovicius, Sadauskiene et al., Selective induction of IL-6 by aluminum-induced oxidative stress can be prevented by selenium, J. Trace Elem. Med. Biol
Vázquez, Vélez, Devesa, In vitro evaluation of inorganic mercury and methylmercury effects on the intestinal epithelium permeability, Food Chem. Toxicol
Waalkes, Coogan, Barter, Toxicological principles of metal carcinogenesis with special emphasis on cadmium, Crit. Rev. Toxicol
Wagner, Accumulation of cadmium in crop plants and its consequences to human health, Adv. Agron
Wang, Mukherjee, Park, Associations of cumulative exposure to heavy metal mixtures with obesity and its comorbidities among US adults in NHANES 2003-2014, Environ. Int
Wiggers, Peçanha, Briones, Perez-Giron, Miguel et al., Low mercury concentrations cause oxidative stress and endothelial dysfunction in conductance and resistance arteries, Am. J. Physiol. -Heart Circ. Physiol
Wood, Beckham, Yosioka, Darban, Watson, β-Carotene and selenium supplementation enhances immune response in aged humans, Integr. Med
Yoshizawa, Rimm, Morris, Spate, Hsieh et al., Mercury and the risk of coronary heart disease in men, N. Engl. J. Med
Yu, Duan, Li, Yu, Jin et al., Combined toxicity of amorphous silica nanoparticles and methylmercury to human lung epithelial cells, Ecotoxicol. Environ. Saf
Zhang, Saad, Taylor, Rayman, Selenium and selenoproteins in viral infection with potential relevance to COVID-19, Redox Biol
Zhang, Taylor, Bennett, Saad, Rayman, Association between regional selenium status and reported outcome of COVID-19 cases in China, Am. J. Clin. Nutr
Zhang, Taylor, Bennett, Saad, Rayman, Association between regional selenium status and reported outcome of COVID-19 cases in China, Am. J. Clin. Nutr
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