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All Studies   Meta Analysis    Recent:   

Turmeric as a Possible Treatment for COVID-19-Induced Anosmia and Ageusia

Chabot et al., Cureus, doi:10.7759/cureus.17829
Sep 2021  
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Small case study of 2 patients, showing significant improvement in taste and smell shortly after one dose of a turmeric supplement. Authors note that the risk of one dose is low in healthy individuals not on medications metabolized by cytochromes P450, and the potential benefit is high.
Chabot et al., 8 Sep 2021, peer-reviewed, 2 authors.
This PaperCurcuminAll
Turmeric as a Possible Treatment for COVID-19-Induced Anosmia and Ageusia
A Bert Chabot, Margaret P Huntwork
Cureus, doi:10.7759/cureus.17829
The coronavirus disease 2019 (COVID-19) pandemic has caused a calamitous perturbation of society worldwide. Anosmia and ageusia (or hyposmia and dysgeusia) have been recognized as two common expressions of COVID-19 infection that linger for days to weeks, and in rare cases are thought to be immutable. Time alone has hitherto proven most effective in their restoration, but turmeric, long believed by some to have medicinal properties, may be a swifter and surer alleviator of anosmia and ageusia. This case series reports the speedy and consequential restoration of taste and smell in two subjects infected with COVID-19 following ingestion of one 1000 mg dose of a turmeric supplement. In view of this, we propose that turmeric be considered in the treatment of anosmia and ageusia caused by COVID-19 infection.
Additional Information Disclosures Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services
References
Brann, Tsukahara, Weinreb, Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia, Sci Adv, doi:10.1101/2020.03.25.009084
Das, Sarmah, Lyndem, Roy, An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study, J Biomol Struct Dyn, doi:10.1080/07391102.2020.1763201
Hay, Lucariello, Contieri, Esposito, Luca et al., Therapeutic effects of turmeric in several diseases: an overview, Chem Biol Interact, doi:10.1016/j.cbi.2019.108729
Jena, Kanungo, Nayak, Chainy, Dandapat, Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies, Sci Rep, doi:10.1038/s41598-021-81462-7
Lee, Lee, Wee, Kim, Prognosis of postviral olfactory loss: follow-up study for longer than one year, Am J Rhinol Allergy, doi:10.2500/ajra.2014.28.4102
Meinhardt, Radke, Dittmayer, Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19, Nat Neurosci, doi:10.1038/s41593-020-00758-5
Paderno, Mattavelli, Rampinelli, Olfactory and gustatory outcomes in COVID-19: a prospective evaluation in nonhospitalized subjects, Otolaryngol Head Neck Surg, doi:10.1177/0194599820939538
Soleimani, Sahebkar, Hosseinzadeh, Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: review, Phyt other Res, doi:10.1002/ptr.6054
Vaira, Salzano, Fois, Piombino, Riu, Potential pathogenesis of ageusia and anosmia in COVID-19 patients, Int Forum Allergy Rhinol, doi:10.1002/alr.22593
Whitcroft, Hummel, Olfactory dysfunction in COVID-19: diagnosis and management, JAMA, doi:10.1001/jama.2020.8391
White, Pasupuleti, Roman, Li, Hernandez, Oral turmeric/curcumin effects on inflammatory markers in chronic inflammatory diseases: a systematic review and meta-analysis of randomized controlled trials, Pharmacol Res, doi:10.1016/j.phrs.2019.104280
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