Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital
Capone et al.,
Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital,
Cureus, doi:10.7759/cureus.9809
Retrospective 102 ICU patients in the USA, 73 receiving vitamin C and zinc, showing a negative correlation of treatment with mortality, but not reaching statistical significance (p = 0.31).
Capone et al., 17 Aug 2021, USA, peer-reviewed, 11 authors.
Abstract: Open Access Original
Article
DOI: 10.7759/cureus.9809
Characterization of Critically Ill COVID-19
Patients at a Brooklyn Safety-Net Hospital
Stephen Capone 1, 2 , Shogik Abramyan 2 , Brent Ross 2 , Joshua Rosenberg 3 , John Zeibeq 3 ,
Viswanath Vasudevan 3 , Reza Samad 3 , Louis Gerolemou 3 , Evgeny Pinelis 3 , James Gasperino
3 , Jose Orsini 3
1. Medicine, St. George's University School of Medicine, St. George, GRD 2. Department of Surgery, The
Brooklyn Hospital Center, Academic Affiliate of the Icahn School of Medicine at Mount Sinai, Clinical
Affiliate of the Mount Sinai Hospital, Brooklyn, USA 3. Division of Critical Care Medicine, The Brooklyn
Hospital Center, Academic Affiliate of the Icahn School of Medicine at Mount Sinai, Clinical Affiliate of
the Mount Sinai Hospital, Brooklyn, USA
Corresponding author: Stephen Capone, scapone01@gmail.com
Abstract
Background
The novel coronavirus disease 2019 (COVID-19) pandemic continues to spread across the
country with over 3 million cases and 150,000 deaths in the United States as of July
2020. Outcomes have been poor, with reported admission rates to the intensive care team of
5% in China and mortality among critically ill patients of 50% in Seattle. Here we explore the
disease characteristics in a Brooklyn safety-net hospital affected by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) pandemic.
Methods
A retrospective chart review of COVID-19 positive patients at The Brooklyn Hospital Center
who were treated by the intensive care team prior to April 20, 2020. Data was extracted from the
electronic health record, analyzed and correlated for outcome.
Results
Received 07/29/2020
Review began 07/31/2020
Impact of various clinical treatments was assessed, showing no change in median overall
survival (OS) of both hydroxychloroquine with azithromycin or vitamin C with
zinc. Supplemental therapies were used in selected patients, and some were shown to increase
median OS and patients requiring vasopressor support or invasive mechanical ventilation
showed decreased OS. There was no statistically significant difference in overall survival based
on ethnicity, healthcare status, or individual medical comorbidities, although a negative trend
exists for diabetes. Despite this, there is a trend towards increasingly poor prognosis based on
the number of comorbidities and Class 3 obesity.
Review ended 08/06/2020
Published 08/17/2020
© Copyright 2020
Capone et al. This is an open access
article distributed under the terms of
the Creative Commons Attribution
License CC-BY 4.0., which permits
unrestricted use, distribution, and
reproduction in any medium, provided
Conclusions
Despite the fact that we show no significant differences in mortality based on ethnicity,
insurance status, or individual medical comorbidities, we show a high overall mortality. There
is also a trend towards increased overall mortality in Class 3 obesity, which should be further
investigated. We suggest that these findings may be attributed to both socioeconomic factors
and an increased incidence of total medical comorbidities in our patient population.
the original author and source are
credited.
How to cite this article
Capone S, Abramyan S, Ross B, et al. (August 17, 2020) Characterization of Critically Ill COVID-19
Patients at a Brooklyn Safety-Net Hospital. Cureus 12(8): e9809. DOI 10.7759/cureus.9809
Categories: Internal Medicine, Infectious Disease
Keywords: coronavirus, sars-cov-2 (severe acute..
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