Abstract: Open Access Original Article DOI: 10.7759/cureus.9809 Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital Stephen Capone 1, 2 , Shogik Abramyan 2 , Brent Ross 2 , Joshua Rosenberg 3 , John Zeibeq 3 , Viswanath Vasudevan 3 , Reza Samad 3 , Louis Gerolemou 3 , Evgeny Pinelis 3 , James Gasperino 3 , Jose Orsini 3 1. Medicine, St. George's University School of Medicine, St. George, GRD 2. Department of Surgery, The Brooklyn Hospital Center, Academic Affiliate of the Icahn School of Medicine at Mount Sinai, Clinical Affiliate of the Mount Sinai Hospital, Brooklyn, USA 3. Division of Critical Care Medicine, The Brooklyn Hospital Center, Academic Affiliate of the Icahn School of Medicine at Mount Sinai, Clinical Affiliate of the Mount Sinai Hospital, Brooklyn, USA Corresponding author: Stephen Capone, scapone01@gmail.com Abstract Background The novel coronavirus disease 2019 (COVID-19) pandemic continues to spread across the country with over 3 million cases and 150,000 deaths in the United States as of July 2020. Outcomes have been poor, with reported admission rates to the intensive care team of 5% in China and mortality among critically ill patients of 50% in Seattle. Here we explore the disease characteristics in a Brooklyn safety-net hospital affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Methods A retrospective chart review of COVID-19 positive patients at The Brooklyn Hospital Center who were treated by the intensive care team prior to April 20, 2020. Data was extracted from the electronic health record, analyzed and correlated for outcome. Results Received 07/29/2020 Review began 07/31/2020 Impact of various clinical treatments was assessed, showing no change in median overall survival (OS) of both hydroxychloroquine with azithromycin or vitamin C with zinc. Supplemental therapies were used in selected patients, and some were shown to increase median OS and patients requiring vasopressor support or invasive mechanical ventilation showed decreased OS. There was no statistically significant difference in overall survival based on ethnicity, healthcare status, or individual medical comorbidities, although a negative trend exists for diabetes. Despite this, there is a trend towards increasingly poor prognosis based on the number of comorbidities and Class 3 obesity. Review ended 08/06/2020 Published 08/17/2020 © Copyright 2020 Capone et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided Conclusions Despite the fact that we show no significant differences in mortality based on ethnicity, insurance status, or individual medical comorbidities, we show a high overall mortality. There is also a trend towards increased overall mortality in Class 3 obesity, which should be further investigated. We suggest that these findings may be attributed to both socioeconomic factors and an increased incidence of total medical comorbidities in our patient population. the original author and source are credited. How to cite this article Capone S, Abramyan S, Ross B, et al. (August 17, 2020) Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital. Cureus 12(8): e9809. DOI 10.7759/cureus.9809 Categories: Internal Medicine, Infectious Disease Keywords: coronavirus, sars-cov-2 (severe acute..