Analgesics
Antiandrogens
Antihistamines
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
PPIs
Paxlovid
Quercetin
Remdesivir
Thermotherapy
Vitamins
More

Other
Feedback
Home
 
next
study
previous
study
c19early.org COVID-19 treatment researchVitamin DVitamin D (more..)
Melatonin Meta
Metformin Meta
Antihistamines Meta
Azvudine Meta Molnupiravir Meta
Bromhexine Meta
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis       

Vitamin D in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients with non-invasive ventilation support

Barassi et al., Panminerva Med., doi:10.23736/S0031-0808.21.04277-4
Jan 2021  
  Post
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
Mortality 65% Improvement Relative Risk Ventilation 65% Vitamin D for COVID-19  Barassi et al.  Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Retrospective 118 patients in Italy Lower mortality (p=0.44) and ventilation (p=0.15), not sig. c19early.org Barassi et al., Panminerva Med., January 2021 Favorsvitamin D Favorscontrol 0 0.5 1 1.5 2+
Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020, now with p < 0.00000000001 from 122 studies, recognized in 9 countries.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 112 treatments. c19early.org
Retrospective 118 consecutive hospitalized PCR+ patients in Italy showing higher ventilation and mortality with vitamin D deficiency.
This is the 43rd of 211 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 248,027,826 vigintillion).
risk of death, 64.9% lower, RR 0.35, p = 0.44, high D levels 1 of 31 (3.2%), low D levels 8 of 87 (9.2%), NNT 17, >20ng/mL.
risk of mechanical ventilation, 64.9% lower, RR 0.35, p = 0.15, high D levels 2 of 31 (6.5%), low D levels 16 of 87 (18.4%), NNT 8.4, >20ng/mL.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Barassi et al., 25 Jan 2021, retrospective, Italy, peer-reviewed, 8 authors.
This PaperVitamin DAll
{ 'indexed': { 'date-parts': [[2023, 12, 28]], 'date-time': '2023-12-28T10:19:49Z', 'timestamp': 1703758789518}, 'reference-count': 57, 'publisher': 'Edizioni Minerva Medica', 'issue': '1', 'content-domain': {'domain': [], 'crossmark-restriction': False}, 'published-print': {'date-parts': [[2023, 3]]}, 'DOI': '10.23736/s0031-0808.21.04277-4', 'type': 'journal-article', 'created': {'date-parts': [[2021, 9, 14]], 'date-time': '2021-09-14T08:06:33Z', 'timestamp': 1631606793000}, 'source': 'Crossref', 'is-referenced-by-count': 11, 'title': 'Vitamin D in SARS-CoV-2 patients with non-invasive ventilation support', 'prefix': '10.23736', 'volume': '65', 'author': [ {'given': 'Alessandra', 'family': 'BARASSI', 'sequence': 'first', 'affiliation': []}, {'given': 'Raffaele', 'family': 'PEZZILLI', 'sequence': 'additional', 'affiliation': []}, {'given': 'Michele', 'family': 'MONDONI', 'sequence': 'additional', 'affiliation': []}, {'given': 'Rocco F.', 'family': 'RINALDO', 'sequence': 'additional', 'affiliation': []}, {'given': 'Matteo', 'family': 'DAVÌ', 'sequence': 'additional', 'affiliation': []}, {'given': 'Mario', 'family': 'COZZOLINO', 'sequence': 'additional', 'affiliation': []}, {'given': 'Gianvico', 'family': 'MELZI D’ERIL', 'sequence': 'additional', 'affiliation': []}, {'given': 'Stefano', 'family': 'CENTANNI', 'sequence': 'additional', 'affiliation': []}], 'member': '17149', 'reference': [ { 'key': '10.23736/S0031-0808.21.04277-4_ref001', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S0140-6736(20)30183-5'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref002', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMoa2001017'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref003', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S0140-6736(20)30154-9'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref004', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMoa2001316'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref005', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMc2001468'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref006', 'doi-asserted-by': 'publisher', 'DOI': '10.1001/jama.2020.2565'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref007', 'unstructured': 'World Health Organization. Coronavirus Disease (COVID-19) pandemic; ' '2022. Available from: ' 'https://www.who.int/emergencies/diseases/novel-coronavirus-2019 [cited ' '2022, Feb 14].'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref008', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMoa2002032'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref009', 'doi-asserted-by': 'publisher', 'DOI': '10.1056/NEJMra070553'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref010', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/rmv.2032'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref011', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.ijantimicag.2020.106137'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref012', 'doi-asserted-by': 'publisher', 'DOI': '10.3389/fimmu.2018.00458'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref013', 'doi-asserted-by': 'publisher', 'DOI': '10.1183/09031936.03.00080203'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref014', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.amjmed.2007.10.033'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref015', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S0140-6736(20)30211-7'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref016', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/S0140-6736(20)30557-2'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref017', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/jmv.25727'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref018', 'unstructured': 'Società Italiana di Malattie Infettive e Tropicali. Linee guida sulla ' 'gestione terapeutica e di support per pazienti con infezione da ' 'coronavirus COVID-19; 2020 [Internet]. Available from: ' 'https://www.omceoch.it/storage/attachments/Ebka.COVID19%20linee%20guida%20trattamento%2001MAR.pdf.pdf ' '[cited 2022, Feb 14].'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref019', 'doi-asserted-by': 'publisher', 'DOI': '10.1210/jc.2010-0606'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref020', 'doi-asserted-by': 'publisher', 'DOI': '10.1079/BJN2003837'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref021', 'doi-asserted-by': 'publisher', 'DOI': '10.1155/2018/5813095'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref022', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/mnfr.201000174'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref023', 'doi-asserted-by': 'publisher', 'DOI': '10.1111/cei.13042'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref024', 'doi-asserted-by': 'publisher', 'DOI': '10.1017/S0950268820000151'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref025', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/ppul.24699'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref026', 'doi-asserted-by': 'publisher', 'DOI': '10.1126/science.1123933'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref027', 'doi-asserted-by': 'publisher', 'DOI': '10.4049/jimmunol.0803736'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref028', 'doi-asserted-by': 'publisher', 'DOI': '10.1017/S0029665111003351'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref029', 'doi-asserted-by': 'publisher', 'DOI': '10.1111/apm.12982'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref030', 'doi-asserted-by': 'publisher', 'DOI': '10.3390/nu12010236'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref031', 'first-page': '59', 'article-title': 'Vitamin D deficiency in HIV: a shadow on long-term management?', 'volume': '16', 'author': 'Orkin C', 'year': '2014', 'journal-title': 'AIDS Rev'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref032', 'doi-asserted-by': 'publisher', 'DOI': '10.1089/aid.2011.0244'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref033', 'doi-asserted-by': 'publisher', 'DOI': '10.1084/jem.20200678'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref034', 'doi-asserted-by': 'publisher', 'DOI': '10.1007/s00414-020-02318-9'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref035', 'doi-asserted-by': 'publisher', 'DOI': '10.1126/science.1208421'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref036', 'doi-asserted-by': 'publisher', 'DOI': '10.1172/jci.insight.138070'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref037', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.cmi.2020.05.019'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref038', 'unstructured': 'Frieden T. Former CDC Chief Dr. Tom Frieden: Coronavirus infection risk ' 'may be reduced by Vitamin D; 2020 [Internet]. Available from: ' 'https://www.foxnews.com/opinion/former-cdc-chief-tom-frieden-coronavirus-risk-may-be-reduced-with-vitamin-d ' '[cited 2022, Feb 14].'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref039', 'doi-asserted-by': 'publisher', 'DOI': '10.1139/cjpp-2014-0352'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref040', 'doi-asserted-by': 'publisher', 'DOI': '10.12703/P6-118'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref041', 'doi-asserted-by': 'publisher', 'DOI': '10.1371/journal.pone.0175517'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref042', 'doi-asserted-by': 'publisher', 'DOI': '10.1093/infdis/jiu074'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref043', 'doi-asserted-by': 'publisher', 'DOI': '10.3390/nu12051359'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref044', 'doi-asserted-by': 'publisher', 'DOI': '10.1556/OH.2011.29187'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref045', 'doi-asserted-by': 'publisher', 'DOI': '10.1001/jama.2020.4683'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref046', 'first-page': '81', 'article-title': 'Vitamin D and Inflammation: Potential Implications for Severity of ' 'Covid-19', 'volume': '113', 'author': 'Laird E', 'year': '2020', 'journal-title': 'Ir Med J'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref047', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/jmv.25770'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref048', 'doi-asserted-by': 'publisher', 'DOI': '10.1089/aid.2012.0120'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref049', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.ijtb.2018.05.018'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref050', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/jmv.25871'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref051', 'doi-asserted-by': 'publisher', 'DOI': '10.1016/j.jcv.2020.104370'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref052', 'doi-asserted-by': 'publisher', 'DOI': '10.1017/S000711451800209X'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref053', 'doi-asserted-by': 'publisher', 'DOI': '10.3390/jcm8030311'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref054', 'doi-asserted-by': 'publisher', 'DOI': '10.1111/mcn.12987'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref055', 'doi-asserted-by': 'publisher', 'DOI': '10.1371/journal.ppat.1008341'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref056', 'doi-asserted-by': 'publisher', 'DOI': '10.1002/jmv.25707'}, { 'key': '10.23736/S0031-0808.21.04277-4_ref057', 'unstructured': 'TILDA - the Irish Longitudinal Study of Ageing. Vitamin D deficiency in ' 'Ireland - implications for COVID-19. Results from the Irish Longitudinal ' 'Study on Ageing (TILDA); 2020 [Internet]. Available from: ' 'https://tilda.tcd.ie/publications/reports/pdf/Report_Covid19VitaminD.pdf ' '[cited 2022, Feb 14].'}], 'container-title': 'Panminerva Medica', 'original-title': [], 'link': [ { 'URL': 'https://www.minervamedica.it/pdf.php?cod=R41Y2023N01A0023', 'content-type': 'unspecified', 'content-version': 'vor', 'intended-application': 'similarity-checking'}], 'deposited': { 'date-parts': [[2023, 3, 14]], 'date-time': '2023-03-14T09:27:22Z', 'timestamp': 1678786042000}, 'score': 1, 'resource': {'primary': {'URL': 'https://www.minervamedica.it/index2.php?show=R41Y2023N01A0023'}}, 'subtitle': [], 'short-title': [], 'issued': {'date-parts': [[2023, 3]]}, 'references-count': 57, 'journal-issue': {'issue': '1'}, 'URL': 'http://dx.doi.org/10.23736/S0031-0808.21.04277-4', 'relation': {}, 'ISSN': ['0031-0808', '1827-1898'], 'subject': ['General Medicine'], 'container-title-short': 'Panminerva Med', 'published': {'date-parts': [[2023, 3]]}}
Loading..
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit