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Vitamin D in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients with non-invasive ventilation support

Barassi et al., Panminerva Med., doi:10.23736/S0031-0808.21.04277-4
Jan 2021  
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Mortality 65% Improvement Relative Risk Ventilation 65% Vitamin D for COVID-19  Barassi et al.  Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Retrospective 118 patients in Italy Lower mortality (p=0.44) and ventilation (p=0.15), not sig. c19early.org Barassi et al., Panminerva Med., January 2021 Favorsvitamin D Favorscontrol 0 0.5 1 1.5 2+
Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020, now with p < 0.00000000001 from 122 studies, recognized in 9 countries.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 109 treatments. c19early.org
Retrospective 118 consecutive hospitalized PCR+ patients in Italy showing higher ventilation and mortality with vitamin D deficiency.
This is the 43rd of 209 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 293,154,636 vigintillion).
risk of death, 64.9% lower, RR 0.35, p = 0.44, high D levels 1 of 31 (3.2%), low D levels 8 of 87 (9.2%), NNT 17, >20ng/mL.
risk of mechanical ventilation, 64.9% lower, RR 0.35, p = 0.15, high D levels 2 of 31 (6.5%), low D levels 16 of 87 (18.4%), NNT 8.4, >20ng/mL.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Barassi et al., 25 Jan 2021, retrospective, Italy, peer-reviewed, 8 authors.
This PaperVitamin DAll
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