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The association between dietary intakes of zinc, vitamin C and COVID-19 severity and related symptoms: A cross-sectional study

Asoudeh et al., Clinical Nutrition ESPEN, doi:10.1016/j.clnesp.2023.03.013
Mar 2023  
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Severe case 69% Improvement Relative Risk Vitamin C for COVID-19  Asoudeh et al.  Prophylaxis Is prophylaxis with vitamin C beneficial for COVID-19? Retrospective 250 patients in Iran (June - September 2021) Lower severe cases with vitamin C (p=0.0028) c19early.org Asoudeh et al., Clinical Nutrition ESPEN, Mar 2023 Favorsvitamin C Favorscontrol 0 0.5 1 1.5 2+
Vitamin C for COVID-19
6th treatment shown to reduce risk in September 2020
 
*, now with p = 0.000000028 from 72 studies, recognized in 12 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,800+ studies for 102 treatments. c19early.org
Retrospective 250 recovered COVID-19 patients, showing lower risk of severe cases with higher vitamin C intake.
This is the 58th of 72 COVID-19 controlled studies for vitamin C, which collectively show efficacy with p=0.000000028 (1 in 35 million).
21 studies are RCTs, which show efficacy with p=0.0012.
Study covers zinc and vitamin C.
risk of severe case, 69.0% lower, OR 0.31, p = 0.003, adjusted per study, T3 vs. T1, multivariable, model 3, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Asoudeh et al., 21 Mar 2023, retrospective, Iran, peer-reviewed, 10 authors, study period June 2021 - September 2021.
This PaperVitamin CAll
The association between dietary intakes of zinc, vitamin C and COVID-19 severity and related symptoms: A cross-sectional study
Farzaneh Asoudeh, Seyed Armin Ebrahimzadeh, Seyed Mojtaba Ghoreishy, Seyed Hossein Imani, Seyed Mohammad Mousavi, Nikan Zargarzadeh, Somaye Rigi, Emma Persad, Mohsen Taghizadeh, PhD Alireza Milajerdi
Clinical Nutrition ESPEN, doi:10.1016/j.clnesp.2023.03.013
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Conflict of interest: The authors have no conflicts of interest to declare. Author contributions: FA, SMM, SMG, NZ, SR and EP contributed to the conception and design of the study, data collection, and statistical analysis and drafting of the manuscript; AM and MT contributed in data collection and manuscript drafting. All authors read and approved the final manuscript. J o u r n a l P r e -p r o o f 0.23 Vitamin B6 (mg/day)
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