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The risk of up normal values of two parameters obesity and vitamin D in incidence of coronavirus disease-19 among Iraqi patients

Allami et al., 1st Samarra International Conference for Pure and Applied Sciences (SICPS2021), doi:10.1063/5.0121166

Nov 2022

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Vitamin D for COVID-19

8th treatment shown to reduce risk in October 2020, now with p < 0.00000000001 from 122 studies, recognized in 9 countries.

Lower risk for mortality, ICU, hospitalization, progression, recovery, cases, and viral clearance.

No treatment is 100% effective. Protocols combine treatments.

5,100+ studies for 112 treatments. c19early.org

Retrospective 86 COVID-19 hospitalized patients and 86 healthy controls in Iraq, showing COVID-19 cases associated with severe vitamin D deficiency.

This is the 150th of 211 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 248,027,826 vigintillion).

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risk of hospitalization, 92.5% lower, OR 0.07, p < 0.001, high D levels (≥10ng/mL) 91, low D levels (<10ng/mL) 80, adjusted per study, inverted to make OR<1 favor high D levels (≥10ng/mL), case control OR, multivariable.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates

Allami et al., 8 Nov 2022, retrospective, Iraq, peer-reviewed, 6 authors. Contact: ahmed.suleiman@uoanbar.edu.iq.

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The Risk of Up Normal Values of Two Parameters Obesity and Vitamin D in Incidence of Coronavirus Disease-19 Among Iraqi Patients

Risala H Allami, Ahmed A Suleiman, Raghad S Mouhamad, Maha H Abdullah, Mustafa Y Alsudani, Ali H Adhiah

The new epidemic of coronavirus disease-19 outbreak has caused rapid morbidity and mortality rates worldwide, and health parameters have been proposed to influence disease progression. Among these parameters are index of body mass (BMI) and D vitamin. 86 patients with same number of control were studied( case-control) to find the relationship between the BMI, vitamin D and risk of COVID-19. Vitamin D (25-hydroxyvitamin D) serum level was estimated by ELISA. Results revealed that the age mean value was elevated significantly in cases compared to normal persons , and 50% of patients were 50 years of age or older. patients BMI were higher significantly in comparison with controls, and most of patients were overweight/obese (76.7%). The Vitamin D level decreased in patients significantly compared to control, and most of patients were severely-deficient (75.6%). Logistic-regression-analysis depicted a high risk of COVID-19 in obese cases (OR= 26.39; 95% interval of confidence [CI]: 7.02-99.24; p < 0.001), and in patients with severe deficient in vitamin D (OR = 13.34; 95% CI: 6.32-28.19; < 0.001). Moreover, overweight/obese patients severely deficient in vitamin D were at high risk of developing COVID-19 infection (OR = 230.55; 95% CI: 43.98-1208.67; p < 0.001). Curve analysis of ROC(Receiver-operating-characteristic) showed that BMI and vitamin D occupied under curve significant area (0.770 and 0.864, respectively). In conclusions, the study indicated that individuals who were overweight/obese and severely deficient in vitamin D were more susceptible to develop COVID-19.

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