Comparison of Length of Hospital Stay and Routine Laboratory Parameters in Covid-19 Patients With and Without Serum Vitamin D Deficiency
Ayşe Umay, Birsen Aydin, Şirin Çetin, Selçuk Sezikli
Journal of Contemporary Medicine, doi:10.16899/jcm.1319088
Although some recent studies have shown that serum 25-hydroxyvitamin D (25(OH)D) may be effective on the course of COVID-19 disease, the results obtained are still controversial. Therefore, in this study, it was aimed to examine whether there are differences in terms of age, gender, length of hospital stay, biochemical and hematological parameters between those with and without serum 25(OH)D deficiency in COVID-19 patients. Material and Method: The data of 413 patients hospitalized in Ankara Pursaklar State Hospital whose COVID-19 positivity was revealed by PCR test were evaluated retrospectively. Those with less than serum 25(OH)D (<20 ng/mL) were considered as vitamin D deficient group. Results: It was observed that there was a significant difference between the groups with and without serum 25(OH)D deficiency in terms of biochemical parameters total bilirubin (p=0.007), potassium (<0.05) and glucose (p=0.038) values. CRP (p=0.051) and fibrinogen (p=0.048) values, which are factors of inflammation and coagulation, were found to be significantly higher in the group with 25(OH)D deficiency. Similarly, hematocrit (p<0.05) and neutrophil count (p<0.001), which are hematological parameters, increased significantly in patients with 25(OH)D deficiency. There were no differences in age, gender and length of hospital stay between the groups with and without 25(OH)D deficiency. Conclusion: Our findings showed that 25(OH)D deficiency in hospitalized COVID-19 patients was associated with some biochemical, hematological and inflammatory factors, but not with age, gender and length of hospital stay.
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