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c19early.org COVID-19 treatment researchLeritrelvirLeritrelvir (more..)
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Summary of COVID-19 leritrelvir studies

Studies   Meta Analysis   Hide extended summaries

40 patient leritrelvir early treatment RCT: 35% faster recovery (p=0.04) and 21% improved viral clearance (p=0.01).
RCT 60 hospitalized COVID-19 patients in China showing imporoved recovery and viral clearance with RAY1216, a 3CLpro inhibitor.

Sep 2023, eClinicalMedicine, https://www.sciencedirect.com/science/article/pii/S2589537023003668, https://c19p.org/wang29

1,359 patient leritrelvir early treatment RCT: 17% improved recovery (p=0.002) and 16% improved viral clearance (p=0.01).
RCT 1,359 COVID-19 outpatients showing faster recovery with leritrelvir monotherapy (without ritonavir), 251 vs. 271 hours, and improved viral clearance. There were no significant differences in adverse events between groups.

Jan 2024, eClinicalMedicine, https://www.sciencedirect.com/science/article/pii/S2589537023005369, https://c19p.org/zhan2
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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