Serum levels of vitamin D and immune system function in patients with COVID-19 admitted to intensive care unit

DOI record: { "DOI": "10.1016/j.genrep.2022.101509", "ISSN": [ "2452-0144" ], "URL": "http://dx.doi.org/10.1016/j.genrep.2022.101509", "alternative-id": [ "S2452014422000176" ], "article-number": "101509", "assertion": [ { "label": "This article is maintained by", "name": "publisher", "value": "Elsevier" }, { "label": "Article Title", "name": "articletitle", "value": "Serum levels of vitamin D and immune system function in patients with COVID-19 admitted to intensive care unit" }, { "label": "Journal Title", "name": "journaltitle", "value": "Gene Reports" }, { "label": "CrossRef DOI link to publisher maintained version", "name": "articlelink", "value": "https://doi.org/10.1016/j.genrep.2022.101509" }, { "label": "Content Type", "name": "content_type", "value": "article" }, { "label": "Copyright", "name": "copyright", "value": "© 2022 Elsevier Inc. All rights reserved." } ], "author": [ { "affiliation": [], "family": "Soltani-Zangbar", "given": "Mohammad Sadegh", "sequence": "first" }, { "affiliation": [], "family": "Mahmoodpoor", "given": "Ata", "sequence": "additional" }, { "affiliation": [], "family": "Dolati", "given": "Sanam", "sequence": "additional" }, { "affiliation": [], "family": "Shamekh", "given": "Ali", "sequence": "additional" }, { "affiliation": [], "family": "Valizadeh", "given": "Sepehr", "sequence": "additional" }, { "affiliation": [], "family": "Yousefi", "given": "Mehdi", "sequence": "additional" }, { "affiliation": [], "family": "Sanaie", "given": "Sarvin", "sequence": "additional" } ], "container-title": [ "Gene Reports" ], "content-domain": { "crossmark-restriction": true, "domain": [ "elsevier.com", "sciencedirect.com" ] }, "created": { "date-parts": [ [ 2022, 1, 15 ] ], "date-time": "2022-01-15T23:52:17Z", "timestamp": 1642290737000 }, "deposited": { "date-parts": [ [ 2022, 2, 11 ] ], "date-time": "2022-02-11T00:47:32Z", "timestamp": 1644540452000 }, "funder": [ { "DOI": "10.13039/501100004366", "award": [ "65213" ], "doi-asserted-by": "publisher", "name": "Tabriz University of Medical Sciences" } ], "indexed": { "date-parts": [ [ 2022, 2, 11 ] ], "date-time": "2022-02-11T01:11:56Z", "timestamp": 1644541916261 }, "is-referenced-by-count": 0, "issn-type": [ { "type": "print", "value": "2452-0144" } ], "issued": { "date-parts": [ [ 2022, 3 ] ] }, "language": "en", "license": [ { "URL": "https://www.elsevier.com/tdm/userlicense/1.0/", "content-version": "tdm", "delay-in-days": 0, "start": { "date-parts": [ [ 2022, 3, 1 ] ], "date-time": "2022-03-01T00:00:00Z", "timestamp": 1646092800000 } } ], "link": [ { "URL": "https://api.elsevier.com/content/article/PII:S2452014422000176?httpAccept=text/xml", "content-type": "text/xml", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://api.elsevier.com/content/article/PII:S2452014422000176?httpAccept=text/plain", "content-type": "text/plain", "content-version": "vor", "intended-application": "text-mining" } ], "member": "78", "original-title": [], "page": "101509", "prefix": "10.1016", "published": { "date-parts": [ [ 2022, 3 ] ] }, "published-print": { "date-parts": [ [ 2022, 3 ] ] }, "publisher": "Elsevier BV", "reference": [ { "DOI": "10.1016/j.imlet.2017.10.003", "article-title": "Intravenous immunoglobulin (IVIG) treatment modulates peripheral blood Th17 and regulatory T cells in recurrent miscarriage patients: Non randomized, open-label clinical trial", "author": "Ahmadi", "doi-asserted-by": "crossref", "first-page": "12", "journal-title": "Immunol Lett.", "key": "10.1016/j.genrep.2022.101509_bb0005", "volume": "192", "year": "2017" }, { "DOI": "10.4014/jmb.2003.03011", "article-title": "Current status of epidemiology, diagnosis, therapeutics, and vaccines for novel coronavirus disease 2019 (COVID-19)", "author": "Ahn", "doi-asserted-by": "crossref", "first-page": "313", "issue": "3", "journal-title": "J. Microbiol. Biotechnol.", "key": "10.1016/j.genrep.2022.101509_bb0010", "volume": "30", "year": "2020" }, { "DOI": "10.1016/j.jiph.2020.06.021", "article-title": "Role of vitamin D in preventing of COVID-19 infection, progression and severity", "author": "Ali", "doi-asserted-by": "crossref", "first-page": "1373", "issue": "10", "journal-title": "J. Infect. Public Health", "key": "10.1016/j.genrep.2022.101509_bb0015", "volume": "13", "year": "2020" }, { "DOI": "10.1007/s00210-020-01911-4", "article-title": "Vitamin D can prevent COVID-19 infection-induced multiple organ damage", "author": "Aygun", "doi-asserted-by": "crossref", "first-page": "1157", "issue": "7", "journal-title": "Naunyn Schmiedeberg's Arch. Pharmacol.", "key": "10.1016/j.genrep.2022.101509_bb0020", "volume": "393", "year": "2020" }, { "DOI": "10.3390/molecules25225346", "article-title": "Mini-review on the roles of vitamin C, vitamin D, and selenium in the immune system against COVID-19", "author": "Bae", "doi-asserted-by": "crossref", "first-page": "5346", "issue": "22", "journal-title": "Molecules", "key": "10.1016/j.genrep.2022.101509_bb0025", "volume": "25", "year": "2020" }, { "DOI": "10.1016/j.chembiol.2013.12.016", "article-title": "Vitamin D metabolism, mechanism of action, and clinical applications", "author": "Bikle", "doi-asserted-by": "crossref", "first-page": "319", "issue": "3", "journal-title": "Chem Biol.", "key": "10.1016/j.genrep.2022.101509_bb0030", "volume": "21", "year": "2014" }, { "DOI": "10.1093/jtm/taaa008", "article-title": "Pneumonia of unknown etiology in Wuhan, China: potential for international spread via commercial air travel", "author": "Bogoch", "doi-asserted-by": "crossref", "issue": "2", "journal-title": "J. Travel Med.", "key": "10.1016/j.genrep.2022.101509_bb0035", "volume": "27", "year": "2020" }, { "DOI": "10.1007/s40618-020-01370-x", "article-title": "Vitamin D deficiency as a predictor of poor prognosis in patients with acute respiratory failure due to COVID-19", "author": "Carpagnano", "doi-asserted-by": "crossref", "first-page": "765", "issue": "4", "journal-title": "J. Endocrinol. Investig.", "key": "10.1016/j.genrep.2022.101509_bb0040", "volume": "44", "year": "2021" }, { "DOI": "10.1007/s00281-017-0629-x", "article-title": "Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology", "author": "Channappanavar", "doi-asserted-by": "crossref", "first-page": "529", "issue": "5", "journal-title": "Semin. Immunopathol.", "key": "10.1016/j.genrep.2022.101509_bb0045", "volume": "39", "year": "2017" }, { "DOI": "10.1002/jmv.25681", "article-title": "Emerging coronaviruses: genome structure, replication, and pathogenesis", "author": "Chen", "doi-asserted-by": "crossref", "first-page": "418", "issue": "4", "journal-title": "J. Med. Virol.", "key": "10.1016/j.genrep.2022.101509_bb0050", "volume": "92", "year": "2020" }, { "DOI": "10.1080/08820139.2021.1899202", "article-title": "Prevalence of SARS-CoV-2 specific antibodies in asymptomatic hemodialysis patients", "author": "Etemadi", "doi-asserted-by": "crossref", "first-page": "1", "journal-title": "Immunol. Investig.", "key": "10.1016/j.genrep.2022.101509_bb0055", "volume": "23", "year": "2021" }, { "article-title": "ACE2 expression in kidney and testis may cause kidney and testis infection in COVID-19 patients", "author": "Fan", "issue": "7", "journal-title": "Front Med.", "key": "10.1016/j.genrep.2022.101509_bb0060", "volume": "13", "year": "2021" }, { "DOI": "10.1007/s00223-019-00620-2", "article-title": "Vitamin D measurement, the debates continue, new analytes have emerged, developments have variable outcomes", "author": "Fraser", "doi-asserted-by": "crossref", "first-page": "3", "issue": "1", "journal-title": "Calcif. Tissue Int.", "key": "10.1016/j.genrep.2022.101509_bb0065", "volume": "106", "year": "2020" }, { "DOI": "10.1111/ijcp.14675", "article-title": "The role of vitamin D in the age of COVID-19: a systematic review and meta-analysis", "author": "Ghasemian", "doi-asserted-by": "crossref", "issue": "11", "journal-title": "Int. J. Clin. Pract.", "key": "10.1016/j.genrep.2022.101509_bb0070", "volume": "75", "year": "2021" }, { "DOI": "10.3390/nu12040988", "article-title": "Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths", "author": "Grant", "doi-asserted-by": "crossref", "first-page": "988", "issue": "4", "journal-title": "Nutrients", "key": "10.1016/j.genrep.2022.101509_bb0075", "volume": "12", "year": "2020" }, { "DOI": "10.1007/s11154-017-9424-1", "article-title": "The vitamin D deficiency pandemic: approaches for diagnosis, treatment and prevention", "author": "Holick", "doi-asserted-by": "crossref", "first-page": "153", "issue": "2", "journal-title": "Rev. Endocr. Metab. Disord.", "key": "10.1016/j.genrep.2022.101509_bb0080", "volume": "18", "year": "2017" }, { "DOI": "10.1007/s11606-020-05762-w", "article-title": "Review of the clinical characteristics of coronavirus disease 2019 (COVID-19)", "author": "Jiang", "doi-asserted-by": "crossref", "first-page": "1545", "issue": "5", "journal-title": "J. Gen. Intern. Med.", "key": "10.1016/j.genrep.2022.101509_bb0085", "volume": "35", "year": "2020" }, { "DOI": "10.1371/journal.pone.0239252", "article-title": "SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levels", "author": "Kaufman", "doi-asserted-by": "crossref", "issue": "9", "journal-title": "PLoS One", "key": "10.1016/j.genrep.2022.101509_bb0090", "volume": "15", "year": "2020" }, { "article-title": "Vitamin D and inflammation: potential implications for severity of Covid-19", "author": "Laird", "first-page": "81", "issue": "5", "journal-title": "Ir. Med. J.", "key": "10.1016/j.genrep.2022.101509_bb0095", "volume": "113", "year": "2020" }, { "DOI": "10.1016/j.nut.2020.110834", "article-title": "Nutrition support in the time of SARS-CoV-2 (COVID-19)", "author": "Laviano", "doi-asserted-by": "crossref", "journal-title": "Nutrition", "key": "10.1016/j.genrep.2022.101509_bb0100", "volume": "74", "year": "2020" }, { "author": "Li", "key": "10.1016/j.genrep.2022.101509_bb0105", "series-title": "Sunlight and vitamin D in the prevention of coronavirus disease (COVID-19) infection and mortality in the United States", "year": "2020" }, { "DOI": "10.1016/j.molimm.2021.06.001", "article-title": "Reduction and exhausted features of T lymphocytes under serological changes, and prognostic factors in COVID-19 progression", "author": "Mahmoodpoor", "doi-asserted-by": "crossref", "first-page": "121", "journal-title": "Mol. Immunol.", "key": "10.1016/j.genrep.2022.101509_bb0110", "volume": "138", "year": "2021" }, { "article-title": "Covid-19 and children", "author": "Molloy", "first-page": "64", "issue": "4", "journal-title": "Ir. Med. J.", "key": "10.1016/j.genrep.2022.101509_bb0115", "volume": "113", "year": "2020" }, { "DOI": "10.1007/s40618-020-01327-0", "article-title": "Possible role of vitamin D in Covid-19 infection in pediatric population", "author": "Panfili", "doi-asserted-by": "crossref", "first-page": "27", "issue": "1", "journal-title": "J. Endocrinol. Investig.", "key": "10.1016/j.genrep.2022.101509_bb0120", "volume": "44", "year": "2021" }, { "DOI": "10.1186/s41182-020-00277-w", "article-title": "Vitamin d deficiency among patients with COVID-19: case series and recent literature review", "author": "Pinzon", "doi-asserted-by": "crossref", "first-page": "102", "issue": "1", "journal-title": "Trop. Med. Health.", "key": "10.1016/j.genrep.2022.101509_bb0125", "volume": "48", "year": "2020" }, { "DOI": "10.1152/ajpendo.00174.2021", "article-title": "Vitamin D and lumisterol novel metabolites can inhibit SARS-CoV-2 replication machinery enzymes", "author": "Qayyum", "doi-asserted-by": "crossref", "first-page": "E246", "issue": "2", "journal-title": "Am. J. Physiol. Endocrinol. Metab.", "key": "10.1016/j.genrep.2022.101509_bb0130", "volume": "321", "year": "2021" }, { "DOI": "10.1096/fj.12-208975", "article-title": "In vivo evidence for a novel pathway of vitamin D3 metabolism initiated by P450scc and modified by CYP27B1", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "3901", "issue": "9", "journal-title": "FASEB J.", "key": "10.1016/j.genrep.2022.101509_bb0135", "volume": "26", "year": "2012" }, { "DOI": "10.1016/j.mce.2013.12.012", "article-title": "In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "181", "issue": "1–2", "journal-title": "Mol. Cell. Endocrinol.", "key": "10.1016/j.genrep.2022.101509_bb0140", "volume": "383", "year": "2014" }, { "DOI": "10.1096/fj.13-242040", "article-title": "RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy-and 20, 23-dihydroxyvitamin D", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "2775", "issue": "7", "journal-title": "FASEB J.", "key": "10.1016/j.genrep.2022.101509_bb0145", "volume": "28", "year": "2014" }, { "DOI": "10.1038/srep14875", "article-title": "Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "1", "journal-title": "Sci. Rep.", "key": "10.1016/j.genrep.2022.101509_bb0150", "volume": "5", "year": "2015" }, { "DOI": "10.1016/j.jsbmb.2014.11.010", "article-title": "Novel activities of CYP11A1 and their potential physiological significance", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "25", "journal-title": "J. Steroid Biochem. Mol. Biol.", "key": "10.1016/j.genrep.2022.101509_bb0155", "volume": "151", "year": "2015" }, { "DOI": "10.3390/ijms19103072", "article-title": "Differential and overlapping effects of 20, 23 (OH) 2D3 and 1, 25 (OH) 2D3 on gene expression in human epidermal keratinocytes: identification of AhR as an alternative receptor for 20, 23 (OH) 2D3", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "3072", "issue": "10", "journal-title": "Int. J. Mol. Sci.", "key": "10.1016/j.genrep.2022.101509_bb0160", "volume": "19", "year": "2018" }, { "DOI": "10.1007/s12013-020-00913-6", "article-title": "Photoprotective properties of vitamin D and lumisterol hydroxyderivatives", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "165", "issue": "2", "journal-title": "Cell Biochem. Biophys.", "key": "10.1016/j.genrep.2022.101509_bb0165", "volume": "78", "year": "2020" }, { "DOI": "10.1152/ajpendo.00348.2020", "article-title": "Reply to Jakovac and to Rocha et al.: can vitamin D prevent or manage COVID-19 illness?", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "E455", "issue": "2", "journal-title": "Am. J. Physiol. Endocrinol. Metab.", "key": "10.1016/j.genrep.2022.101509_bb0170", "volume": "319", "year": "2020" }, { "DOI": "10.1111/exd.14170", "article-title": "COVID-19 and vitamin D: a lesson from the skin", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "885", "issue": "9", "journal-title": "Exp. Dermatol.", "key": "10.1016/j.genrep.2022.101509_bb0175", "volume": "29", "year": "2020" }, { "DOI": "10.1038/s41435-020-0096-6", "article-title": "Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "150", "issue": "3", "journal-title": "Genes Immun.", "key": "10.1016/j.genrep.2022.101509_bb0180", "volume": "21", "year": "2020" }, { "DOI": "10.1038/s41598-021-87061-w", "article-title": "Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs)", "author": "Slominski", "doi-asserted-by": "crossref", "first-page": "1", "journal-title": "Sci. Rep.", "key": "10.1016/j.genrep.2022.101509_bb0185", "volume": "11", "year": "2021" }, { "article-title": "The significance of CYP11A1 expression in skin physiology and pathology", "author": "Slominski", "issue": "530", "journal-title": "Mol. Cell. Endocrinol.", "key": "10.1016/j.genrep.2022.101509_bb0190", "volume": "15", "year": "2021" }, { "article-title": "Application of newly developed SARS-CoV2 serology test along with real-time PCR for early detection in health care workers and on-time plasma donation", "author": "Soltani-Zangbar", "journal-title": "Gene Rep.", "key": "10.1016/j.genrep.2022.101509_bb0195", "volume": "23", "year": "2021" }, { "DOI": "10.1371/journal.ppat.1007236", "article-title": "Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2", "author": "Song", "doi-asserted-by": "crossref", "issue": "8", "journal-title": "PLoS Pathog.", "key": "10.1016/j.genrep.2022.101509_bb0200", "volume": "14", "year": "2018" }, { "article-title": "Vitamin D3 and its hydroxyderivatives as promising drugs against covid-19: a computational study", "author": "Song", "first-page": "1", "journal-title": "J. Biomol. Struct. Dyn.", "key": "10.1016/j.genrep.2022.101509_bb0205", "volume": "20", "year": "2021" }, { "DOI": "10.1080/17476348.2020.1782197", "article-title": "Ten challenging questions about SARS-CoV-2 and COVID-19", "author": "Teymoori-Rad", "doi-asserted-by": "crossref", "first-page": "881", "issue": "9", "journal-title": "Expert Rev. Respir. Med.", "key": "10.1016/j.genrep.2022.101509_bb0210", "volume": "14", "year": "2020" }, { "DOI": "10.1038/s41577-020-0305-6", "article-title": "In the eye of the COVID-19 cytokine storm", "author": "Vaninov", "doi-asserted-by": "crossref", "first-page": "277", "issue": "5", "journal-title": "Nat. Rev. Immunol.", "key": "10.1016/j.genrep.2022.101509_bb0215", "volume": "20", "year": "2020" }, { "DOI": "10.1001/jama.2020.1585", "article-title": "Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China", "author": "Wang", "doi-asserted-by": "crossref", "first-page": "1061", "issue": "11", "journal-title": "Jama", "key": "10.1016/j.genrep.2022.101509_bb0220", "volume": "323", "year": "2020" }, { "DOI": "10.7861/clinmed.2020-0301", "article-title": "Does vitamin D deficiency increase the severity of COVID-19?", "author": "Weir", "doi-asserted-by": "crossref", "first-page": "e107", "issue": "4", "journal-title": "Clin Med (Lond).", "key": "10.1016/j.genrep.2022.101509_bb0225", "volume": "20", "year": "2020" }, { "DOI": "10.2807/1560-7917.ES.2020.25.3.2000044", "article-title": "Real-time tentative assessment of the epidemiological characteristics of novel coronavirus infections in Wuhan, China, as at 22 January 2020", "author": "Wu", "doi-asserted-by": "crossref", "issue": "3", "journal-title": "Euro Surveill.", "key": "10.1016/j.genrep.2022.101509_bb0230", "volume": "25", "year": "2020" }, { "DOI": "10.1186/s12967-020-02488-5", "article-title": "The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19", "author": "Xu", "doi-asserted-by": "crossref", "first-page": "322", "issue": "1", "journal-title": "J. Transl. Med.", "key": "10.1016/j.genrep.2022.101509_bb0235", "volume": "18", "year": "2020" }, { "DOI": "10.1016/S2213-2600(20)30076-X", "article-title": "Pathological findings of COVID-19 associated with acute respiratory distress syndrome", "author": "Xu", "doi-asserted-by": "crossref", "first-page": "420", "issue": "4", "journal-title": "Lancet Respir. Med.", "key": "10.1016/j.genrep.2022.101509_bb0240", "volume": "8", "year": "2020" }, { "DOI": "10.1007/s12291-020-00950-1", "article-title": "Association of vitamin D status with COVID-19 infection and mortality in the Asia Pacific region: a cross-sectional study", "author": "Yadav", "doi-asserted-by": "crossref", "first-page": "1", "issue": "4", "journal-title": "Indian J Clin Biochem.", "key": "10.1016/j.genrep.2022.101509_bb0245", "volume": "36", "year": "2021" }, { "DOI": "10.1016/j.bcp.2020.113955", "article-title": "Vitamin D attenuates lung injury via stimulating epithelial repair, reducing epithelial cell apoptosis and inhibits TGF-β induced epithelial to mesenchymal transition", "author": "Zheng", "doi-asserted-by": "crossref", "journal-title": "Biochem. Pharmacol.", "key": "10.1016/j.genrep.2022.101509_bb0250", "volume": "177", "year": "2020" } ], "reference-count": 50, "references-count": 50, "relation": {}, "resource": { "primary": { "URL": null } }, "score": 1, "short-container-title": [ "Gene Reports" ], "short-title": [], "source": "Crossref", "subject": [ "Genetics" ], "subtitle": [], "title": [ "Serum levels of vitamin D and immune system function in patients with COVID-19 admitted to intensive care unit" ], "type": "journal-article", "update-policy": "http://dx.doi.org/10.1016/elsevier_cm_policy", "volume": "26" }