Abstract: Söbü et al. COVID-19 and Vitamin D The Journal of Current Pediatrics Güncel Pediatri ORIGINAL ARTICLE ÖZGÜN ARAŞTIRMA Vitamin D Levels of COVID-19 Positive Sypmtomatic Pediatric Cases COVID-19 Pozitif Semptomatik Çocukların D Vitamini Düzeyleri Elif Söbü (0000-0002-2037-7046), Ayşe Karaaslan (0000-0003-4289-3321), Ceren Çetin (0000-0001-6423-7523), Yasemin Akın (0000-0002-7618-7778) University of Health Sciences Turkey, İstanbul Kartal Dr. Lütfi Kırdar City Hospital, Clinic of Pediatrics and Medicine, Istanbul, Turkey Abstract Keywords COVID-19, vitamin D, hypophosphatemia Anah­tar ke­li­me­ler COVID-19, D vitamini, hipofosfatemi Received/Geliş Ta­rihi : 21.12.2020 Accepted/Ka­bul Ta­ri­hi : 02.02.2021 DOI:10.4274/jcp.2021.0002 Ad­dress for Cor­res­pon­den­ce/Ya­zış­ma Ad­re­si (Sorumlu Yazar): Elif Söbü, Sağlık Bilimleri Üniversitesi, İstanbul Kartal Dr. Lütfi Kırdar Şehir Hastanesi, Çocuk Sağlığı ve Hastalıkları, İstanbul, Türkiye J Curr Pediatr 2021;19:9-14 Introduction:Vitamin D is known as a vitamin but also it acts as a prohormone and has many functions. The aim of this study is to investigate the vitamin D levels in pediatric patients with COVID-19. Materials and Methods: A retrospective study was performed in a tertiary education and research hospital in Istanbul, Turkey during the period of Marcht o April 2020. Children diagnosed with symptomatic COVID-19 infection were included in the study. Demographic, clinical and laboratory findings were recorded from patient charts retrospectively. All patients investigated for vitamin D levels. Control group consists of healthy children admitted to pediatric outpatient units for routine check-up in the same season.Thirty children with COVID-19 and 82 healthy children included in this study were compared due to 25-OH vitamin D levels. Results: The median age of COVID-19 positive patients was 11.8 (1.8-17.6) years and the median age of control group was 12.7 (1-16.4) years old. There were 15 (50%) females and 15 (50%) males in infected group and there were 39 (47.5%) females and 43 (52.5%) males control group. Age and gender did not differ among the groups. Median vitamin D level in COVID-19 positive group was 8.9 ng/ml (342 ng/ml) and 18.5 ng/ml (9-40.7 ng/ml) in control group. We detected significantly lower vitamin D values in COVID19(+) group when compared with control group (p<0.001). CT was performed 19 patients in COVID-19 positive group and viral pneumonia was detected in 12(63%) of 19. pneumonia (+) group a 17.4-years-old female patient and a 13.1-years-old male patient had low phosphorus levels by age (2.2 and 2.4 mg/dl). Both of them needed high flow oxygen therapy. None of the other cases needed oxygen therapy. Conclusions: This is the first study to date has measured vitamin D levels in children with COVID-19 in Turkey. We detected significantly lower vitamin D values in COVID-19(+) hospitalized children. Öz Giriş: D vitamini bir vitamin olarak bilinmesine rağmen aynı zamanda bir prohormon görevi görür ve birçok işlevi vardır. Çalışmamızda COVID-19 enfeksiyonu tanısı ile izlenen pediyatrik hastalarda D vitamini düzeylerinin değerlendirilmesi amaçlandı. Gereç ve Yöntem: Çalışmamız Mart-Nisan 2020 tarihlerinde İstanbul’da bir 3. basamak eğitim ve araştırma hastanesinde gerçekleştirildi. Semptomatik COVID-19 enfeksiyonu tanısı alan çocuklar çalışmaya dahil edildi. Demografik, klinik ve laboratuvar bulgular retrospektif olarak hasta dosyalarından kaydedildi. Tüm..