Vitamin D Levels of COVID-19 Positive Sypmtomatic Pediatric Cases
Söbü et al.,
Vitamin D Levels of COVID-19 Positive Sypmtomatic Pediatric Cases,
The Journal of Current Pediatrics, doi:10.4274/jcp.2021.0002
Retrospective 30 hospitalized pediatric COVID-19 patients and 82 healthy controls, showing significantly lower vitamin D levels in COVID-19 patients.
Söbü et al., 2 Feb 2021, peer-reviewed, 4 authors.
Abstract: Söbü et al. COVID-19 and Vitamin D
The Journal of Current Pediatrics
Güncel Pediatri
ORIGINAL ARTICLE
ÖZGÜN ARAŞTIRMA
Vitamin D Levels of COVID-19 Positive Sypmtomatic
Pediatric Cases
COVID-19 Pozitif Semptomatik Çocukların D Vitamini Düzeyleri
Elif Söbü (0000-0002-2037-7046), Ayşe Karaaslan (0000-0003-4289-3321), Ceren Çetin (0000-0001-6423-7523),
Yasemin Akın (0000-0002-7618-7778)
University of Health Sciences Turkey, İstanbul Kartal Dr. Lütfi Kırdar City Hospital, Clinic of Pediatrics and Medicine, Istanbul, Turkey
Abstract
Keywords
COVID-19, vitamin D, hypophosphatemia
Anahtar kelimeler
COVID-19, D vitamini, hipofosfatemi
Received/Geliş Tarihi : 21.12.2020
Accepted/Kabul Tarihi : 02.02.2021
DOI:10.4274/jcp.2021.0002
Address for Correspondence/Yazışma Adresi
(Sorumlu Yazar):
Elif Söbü, Sağlık Bilimleri Üniversitesi,
İstanbul Kartal Dr. Lütfi Kırdar Şehir
Hastanesi, Çocuk Sağlığı ve Hastalıkları,
İstanbul, Türkiye
J Curr Pediatr 2021;19:9-14
Introduction:Vitamin D is known as a vitamin but also it acts as a prohormone
and has many functions. The aim of this study is to investigate the vitamin D levels
in pediatric patients with COVID-19.
Materials and Methods: A retrospective study was performed in a tertiary
education and research hospital in Istanbul, Turkey during the period of Marcht
o April 2020. Children diagnosed with symptomatic COVID-19 infection were
included in the study. Demographic, clinical and laboratory findings were recorded
from patient charts retrospectively. All patients investigated for vitamin D levels.
Control group consists of healthy children admitted to pediatric outpatient units
for routine check-up in the same season.Thirty children with COVID-19 and 82
healthy children included in this study were compared due to 25-OH vitamin D
levels.
Results: The median age of COVID-19 positive patients was 11.8 (1.8-17.6) years
and the median age of control group was 12.7 (1-16.4) years old. There were 15
(50%) females and 15 (50%) males in infected group and there were 39 (47.5%)
females and 43 (52.5%) males control group. Age and gender did not differ among
the groups. Median vitamin D level in COVID-19 positive group was 8.9 ng/ml (342 ng/ml) and 18.5 ng/ml (9-40.7 ng/ml) in control group. We detected significantly
lower vitamin D values in COVID19(+) group when compared with control group
(p<0.001). CT was performed 19 patients in COVID-19 positive group and viral
pneumonia was detected in 12(63%) of 19. pneumonia (+) group a 17.4-years-old
female patient and a 13.1-years-old male patient had low phosphorus levels by age
(2.2 and 2.4 mg/dl). Both of them needed high flow oxygen therapy. None of the
other cases needed oxygen therapy.
Conclusions: This is the first study to date has measured vitamin D levels in
children with COVID-19 in Turkey. We detected significantly lower vitamin D
values in COVID-19(+) hospitalized children.
Öz
Giriş: D vitamini bir vitamin olarak bilinmesine rağmen aynı zamanda bir
prohormon görevi görür ve birçok işlevi vardır. Çalışmamızda COVID-19
enfeksiyonu tanısı ile izlenen pediyatrik hastalarda D vitamini düzeylerinin
değerlendirilmesi amaçlandı.
Gereç ve Yöntem: Çalışmamız Mart-Nisan 2020 tarihlerinde İstanbul’da bir
3. basamak eğitim ve araştırma hastanesinde gerçekleştirildi. Semptomatik
COVID-19 enfeksiyonu tanısı alan çocuklar çalışmaya dahil edildi. Demografik,
klinik ve laboratuvar bulgular retrospektif olarak hasta dosyalarından kaydedildi.
Tüm..
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