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0 0.5 1 1.5 2+ Mortality 89% Improvement Relative Risk Ventilation 75% 2-point improvement 46% Hospitalization time 10% Curcumin  Sankhe et al.  EARLY TREATMENT  RCT Is early treatment with curcumin + combined treatments beneficial for COVID-19? RCT 174 patients in India (October 2020 - March 2021) Improved recovery with curcumin + combined treatments (p=0.002) Sankhe et al., J. Ayurveda and Integra.., Aug 2021 Favors curcumin Favors control

A prospective, multi center, single blind, randomized controlled study evaluating “AyurCoro3” as an adjuvant in the treatment of mild to moderate COVID

Sankhe et al., Journal of Ayurveda and Integrated Medical Sciences, doi:10.21760/jaims.6.4.6
Aug 2021  
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RCT 174 patients in India, 87 treated with AyurCoro-3 (turmeric, gomutra, potassium alum, khadisakhar, bos indicus milk, ghee), showing faster recovery with treatment. EC/NEW/INST/2019/245.
This is the 5th of 20 COVID-19 RCTs for curcumin, which collectively show efficacy with p=0.0000093.
This is the 8th of 26 COVID-19 controlled studies for curcumin, which collectively show efficacy with p=0.000000046 (1 in 22 million).
risk of death, 88.9% lower, RR 0.11, p = 0.12, treatment 0 of 87 (0.0%), control 4 of 87 (4.6%), NNT 22, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of mechanical ventilation, 75.0% lower, RR 0.25, p = 0.37, treatment 1 of 87 (1.1%), control 4 of 87 (4.6%), NNT 29.
risk of no 2-point improvement, 46.5% lower, RR 0.54, p = 0.002, treatment 29 of 87 (33.3%), control 60 of 87 (69.0%), NNT 2.8, inverted to make RR<1 favor treatment, odds ratio converted to relative risk, day 7 mid-recovery.
hospitalization time, 10.0% lower, relative time 0.90, p = 0.40, treatment 87, control 87.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Sankhe et al., 10 Aug 2021, Randomized Controlled Trial, India, peer-reviewed, 8 authors, study period October 2020 - March 2021, this trial uses multiple treatments in the treatment arm (combined with gomutra, potassium alum, khadisakhar, bos indicus milk, ghee) - results of individual treatments may vary.
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This PaperCurcuminAll
A prospective, multi center, single blind, randomized controlled study evaluating "AyurCoro3" as an adjuvant in the treatment of mild to moderate COVID-19 patients
Dr Ajay Prabhakar Sankhe, Nanasaheb Somnath Memane, Vijaykumar P Gawali, Sonal Nanasaheb Memane, Ganesh Ramakrishnan, Mayur Nimba Bagul, Rashmi Tiwari, Vikram Bansal, Ayurveda Head, Dept, Clinical Research Head, Consultant Ayurveda, Somnath Nanasaheb, Vijaykumar P Memane, Gawali, Nanasaheb Sonal, Ganesh Memane, Mayur Nimba Ramakrishnan, Rashmi Bagul, Vikram Tiwari, Bansal
INTRODUCTION The Coronavirus disease (COVID-19) has affected the world worst with over 158 million patients infected
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