The Effect of Oral Care Foams and a Spray on Salivary pH Changes after Exposure to Acidic Beverages in Young Adults

{ 'indexed': {'date-parts': [[2024, 4, 4]], 'date-time': '2024-04-04T01:04:24Z', 'timestamp': 1712192664361}, 'reference-count': 104, 'publisher': 'MDPI AG', 'issue': '4', 'license': [ { 'start': { 'date-parts': [[2024, 4, 3]], 'date-time': '2024-04-03T00:00:00Z', 'timestamp': 1712102400000}, 'content-version': 'vor', 'delay-in-days': 0, 'URL': 'https://creativecommons.org/licenses/by/4.0/'}], 'content-domain': {'domain': [], 'crossmark-restriction': False}, 'abstract': '<jats:p>Soft drinks may have a deleterious effect on dental health due to a high titratable ' 'acidity and a low pH that could be sufficient to induce tooth demineralization. The use of ' 'oral care products immediately after acidic challenge may diminish the erosive potential of ' 'soft drinks. We assessed the effect of oral care foams and a spray on salivary pH changes ' 'after exposure to Coca-Cola® in young adults. Thirty-three consenting eligible patients were ' 'recruited in this double-blind, randomized, crossover study performed in six visits. Baseline ' 'examination included unstimulated salivary flow rate, stimulated salivary buffer capacity, ' 'and the simplified oral hygiene index (OHI-S) assessment. Salivary pH and time for pH ' 'recovery were registered after exposure to Coca-Cola® alone or that followed by the ' 'application of each of the studied products (an oral foam containing hydroxyapatite and ' 'probiotics, an oral foam containing amino fluoride, an alkaline oral spray, and tap water). ' 'Thirty-two patients completed the entire study protocol and were included in the final ' 'analysis. The mean minimum salivary pH and the mean oral clearance rate after rinsing with ' 'Coca-Cola® were 6.3 and 27 min, respectively. Further rinsing with any one of the tested ' 'solutions, including tap water, resulted in a significant improvement in these parameters. ' 'When the pH curves were plotted, the oral care products demonstrated a lower area under the ' 'curve that differed significantly from the area under the curve for Coca-Cola®; tap water did ' 'not differ significantly from Coca-Cola® and oral care products. Minimum salivary pH ' 'correlated positively with salivary buffer capacity and salivation rate, while salivary ' 'clearance correlated with OHI-S plaque scores. In conclusion, the effect of oral care foams ' 'and a spray on minimum salivary pH and salivary clearance after exposure to Coca-Cola® did ' 'not differ significantly among the tested products and tap water. Trial registration ' 'NCT06148662. Funding: none.</jats:p>', 'DOI': '10.3390/dj12040093', 'type': 'journal-article', 'created': {'date-parts': [[2024, 4, 3]], 'date-time': '2024-04-03T07:37:21Z', 'timestamp': 1712129841000}, 'page': '93', 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'The Effect of Oral Care Foams and a Spray on Salivary pH Changes after Exposure to Acidic ' 'Beverages in Young Adults', 'prefix': '10.3390', 'volume': '12', 'author': [ { 'ORCID': 'http://orcid.org/0000-0002-4494-2644', 'authenticated-orcid': False, 'given': 'Maria', 'family': 'Polyakova', 'sequence': 'first', 'affiliation': [ { 'name': 'Department of Therapeutic Dentistry, I.M. Sechenov First Moscow ' 'State Medical University (Sechenov University), 119991 Moscow, ' 'Russia'}]}, { 'ORCID': 'http://orcid.org/0009-0004-9470-1381', 'authenticated-orcid': False, 'given': 'Anna', 'family': 'Egiazaryan', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Therapeutic Dentistry, I.M. Sechenov First Moscow ' 'State Medical University (Sechenov University), 119991 Moscow, ' 'Russia'}]}, { 'given': 'Vladlena', 'family': 'Doroshina', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Therapeutic Dentistry, I.M. Sechenov First Moscow ' 'State Medical University (Sechenov University), 119991 Moscow, ' 'Russia'}]}, { 'ORCID': 'http://orcid.org/0000-0003-3774-3070', 'authenticated-orcid': False, 'given': 'Alexandr', 'family': 'Zaytsev', 'sequence': 'additional', 'affiliation': [ { 'name': 'Institute of Linguistics and Intercultural Communication, I.M. ' 'Sechenov First Moscow State Medical University (Sechenov ' 'University), 119991 Moscow, Russia'}]}, { 'given': 'Alexey', 'family': 'Malashin', 'sequence': 'additional', 'affiliation': [{'name': 'Independent Researcher, 123298 Moscow, Russia'}]}, { 'ORCID': 'http://orcid.org/0000-0003-4445-0858', 'authenticated-orcid': False, 'given': 'Ksenia', 'family': 'Babina', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Therapeutic Dentistry, I.M. Sechenov First Moscow ' 'State Medical University (Sechenov University), 119991 Moscow, ' 'Russia'}]}, { 'ORCID': 'http://orcid.org/0000-0002-1073-7693', 'authenticated-orcid': False, 'given': 'Nina', 'family': 'Novozhilova', 'sequence': 'additional', 'affiliation': [ { 'name': 'Department of Therapeutic Dentistry, I.M. Sechenov First Moscow ' 'State Medical University (Sechenov University), 119991 Moscow, ' 'Russia'}]}], 'member': '1968', 'published-online': {'date-parts': [[2024, 4, 3]]}, 'reference': [ { 'key': 'ref_1', 'doi-asserted-by': 'crossref', 'first-page': '1873', 'DOI': '10.1016/j.ejca.2010.03.025', 'article-title': 'Tea, Coffee, Carbonated Soft Drinks and Upper Gastrointestinal Tract ' 'Cancer Risk in a Large United States Prospective Cohort Study', 'volume': '46', 'author': 'Ren', 'year': '2010', 'journal-title': 'Eur. J. Cancer'}, { 'key': 'ref_2', 'doi-asserted-by': 'crossref', 'first-page': '205', 'DOI': '10.1016/j.amepre.2004.05.005', 'article-title': 'Changes in Beverage Intake between 1977 and 2001', 'volume': '27', 'author': 'Nielsen', 'year': '2004', 'journal-title': 'Am. J. Prev. 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