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Screening Commercial Tea for Rapid Inactivation of Infectious SARS-CoV-2 in Saliva

Morris et al., Food and Environmental Virology, doi:10.1007/s12560-023-09581-0
Jan 2024  
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In Vitro study showing that certain teas can rapidly inactivate SARS-CoV-2 in saliva. At 10 mg/mL infusion, black tea showed the highest reduction (99.9%) of infectious SARS-CoV-2 within 10 seconds. Green, mint medley, eucalyptus mint, and raspberry zinger teas showed 96-99% inactivation at the same concentration. At 40 mg/mL infusions, all five teas inactivated 99.9% of the virus within 10 seconds. Tea polyphenol content, but not pH, significantly correlated with virus reduction. The teas also exhibited preventive effects against SARS-CoV-2 infection of Vero-E6 cells when added before (68-90% reduction), during (99-99.9% reduction), or after (94-98% reduction) virus infection, with the strongest inhibition observed when teas were added at the time of infection. Authors suggest that drinking or gargling tea could be a rapid at-home intervention to reduce infectious SARS-CoV-2 load in the oral cavity and potentially mitigate infection of the oral mucosa.
Morris et al., 31 Jan 2024, peer-reviewed, 2 authors.
In Vitro studies are an important part of preclinical research, however results may be very different in vivo.
This PaperMiscellaneousAll
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Anti-SARS-CoV-2 activity ' 'of various PET-bottled Japanese green teas and tea compounds in vitro. ' 'Archives of Virology, 167, 1547–1557.', 'journal-title': 'Archives of Virology'}, { 'key': '9581_CR26', 'doi-asserted-by': 'publisher', 'first-page': '421', 'DOI': '10.7883/yoken.JJID.2020.902', 'volume': '74', 'author': 'H Nishimura', 'year': '2021', 'unstructured': 'Nishimura, H., Okamoto, M., Dapat, I., Katsumi, M., & Oshitani, H. ' '(2021). Inactivation of SARS-CoV-2 by catechins from green tea. Japanese ' 'Journal of Infectious Diseases, 74, 421–423.', 'journal-title': 'Japanese Journal of Infectious Diseases'}, { 'key': '9581_CR27', 'doi-asserted-by': 'crossref', 'unstructured': 'Ohgitani, E., Shin-Ya, M., Ichitani, M., Kobayashi, M., Takihara, T., ' 'Kawamoto, M., Kinugasa, H., & Mazda, O. (2021a). Rapid inactivation in ' 'vitro of SARS-CoV-2 in saliva by black tea and green tea. 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Gargling with tea ' 'catechin extracts for the prevention of influenza infection in elderly ' 'nursing home residents: A prospective clinical study. Journal of ' 'Alternative and Complementary Medicine, 12, 669–672.', 'journal-title': 'Journal of Alternative and Complementary Medicine'}, { 'key': '9581_CR38', 'doi-asserted-by': 'publisher', 'first-page': '19', 'DOI': '10.1016/j.ijid.2020.04.027', 'volume': '96', 'author': 'H Zhang', 'year': '2020', 'unstructured': 'Zhang, H., Li, H. B., Lyu, J. R., Lei, X. M., Li, W., Wu, G., Lyu, J., & ' 'Dai, Z. M. (2020). Specific ACE2 expression in small intestinal ' 'enterocytes may cause gastrointestinal symptoms and injury after ' '2019-nCoV infection. International Journal of Infectious Diseases, 96, ' '19–24.', 'journal-title': 'International Journal of Infectious Diseases'}, { 'key': '9581_CR39', 'doi-asserted-by': 'publisher', 'first-page': '270', 'DOI': '10.1038/s41586-020-2012-7', 'volume': '579', 'author': 'P Zhou', 'year': '2020', 'unstructured': 'Zhou, P., Yang, X. L., Wang, X. G., Hu, B., Zhang, L., Zhang, W., Si, H. ' 'R., Zhu, Y., Li, B., Huang, C. L., Chen, H. D., Chen, J., Luo, Y., Guo, ' 'H., Jiang, R. D., Liu, M. Q., Chen, Y., Shen, X. R., Wang, X., … Shi, Z. ' 'L. (2020). A pneumonia outbreak associated with a new coronavirus of ' 'probable bat origin. 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