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Prevalence and predictors of vitamin D deficiency in healthy adults

Mitchell et al., Endocr. Pract., 2012, 18:6, 914–923, doi:10.4158/EP12072.OR (Related)
Mitchell et al., Prevalence and predictors of vitamin D deficiency in healthy adults, Endocr. Pract., 2012, 18:6, 914–923, doi:10.4158/EP12072.OR (Related)
Nov 2012   Source   PDF  
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Study of 634 healthy volunteers showing 64% had 25(OH)D ≤ 30 ng/mL. Gender, ethnicity, and multivitamin use were significantly associated with 25(OH)D levels.
Mitchell et al., 1 Nov 2012, peer-reviewed, 4 authors.
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This PaperVitamin DAll
Prevalence and Predictors Ofvitamin D Deficiency in Healthy Adults
MD Deborah M Mitchell, BA Maria P Henao, MD Joel S Finkelstein, Sherri-Ann M. Burnett-Bowie
Endocrine Practice, doi:10.4158/ep12072.or
Objective-Vitamin D deficiency is highly prevalent in high-risk patient populations, but the prevalence among otherwise healthy adults is less well-defined. The goal of this study was to determine the prevalence and predictors of low 25-hydroxyvitamin D [25(OH)D] levels in healthy younger adults. Methods-This was a cross-sectional study of 634 healthy volunteers aged 18-50 years performed between January, 2006 and May, 2008. We measured serum 25(OH) D and parathyroid hormone and recorded demographic variables including age, sex, race, and use of multivitamin supplements. Results-Thirty-nine percent of subjects had 25(OH)D ≤20 ng/mL and 64% had 25(OH)D ≤30 ng/mL. Predictors of lower 25(OH)D levels included male sex, black or Asian race, and lack of multivitamin use (P<0.001 for each predictors). Seasonal variation in 25(OH)D levels was present in the overall cohort but was not observed in multivitamin users. Lower 25(OH)D levels were associated with increased risk of elevated parathyroid hormone. Regression models predicted 25(OH)D levels ≤20 or ≤30 ng/mL with areas under the receiver operating characteristic curves of 0.76 and 0.80, respectively. Conclusion-Low 25(OH)D levels are prevalent in healthy adults and may confer risk of skeletal disease. Black and Asian adults are at increased risk of deficiency and multivitamin use appears partially protective. Our models predicting low 25(OH)D levels may guide decisionmaking regarding whom to screen for vitamin D deficiency.
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Armas, Dowell, Akhter, Ultraviolet-B radiation increases serum 25-hydroxyvitamin D levels: the effect of UVB dose and skin color, J Am Acad Dermatol
Bell, Demay, Burnett-Bowie, The biology and pathology of vitamin D control in bone, J Cell Biochem
Bhan, Rao, Rao, Osteomalacia as a result of vitamin D deficiency, Endocrinol Metab Clin North Am
Bischoff-Ferrari, Giovannucci, Willett, Dietrich, Hughes, Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes, Am J Clin Nutr
Bischoff-Ferrari, Shao, Dawson-Hughes, Hathcock, Giovanucci et al., Benefitrisk assessment of vitamin D supplementation, Osteoporos Int
Bogh, Schmedes, Philipsen, Thieden, Wulf, Vitamin D production after UVB exposure depends on baseline vitamin D and total cholesterol but not on skin pigmentation [correction appears in, J Invest Dermatol
Burnett-Bowie, Leder, Henao, Baldwin, Hayden et al., Randomized trial assessing the effects of ergocalciferol administration on circulating FGF23, Clin J Am Soc Nephrol
Cauley, Danielson, Boudreau, Serum 25-hydroxyvitamin D and clinical fracture risk in a multiethnic cohort of women: the Women's Health Initiative (WHI), J Bone Miner Res
Chapuy, Preziosi, Maamer, Prevalence of vitamin D insufficiency in an adult normal population, Osteoporos Int
Chapuy, Schott, Garnero, Hans, Delmas et al., Healthy elderly French women living at home have secondary hyperparathyroidism and high bone turnover in winter, J Clin Endocrinol Metab
Cosman, Nieves, Dempster, Linsay, Vitamin D economy in blacks, J Bone Miner Res
Dawson-Hughes, Harris, Krall, Dallal, Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older, N Engl J Med
Durazo-Arvizu, Hughes, Sempos, Three-phase model harmonizes estimates of the maximal suppression of parathyroid hormone by 25-hydroxyvitamin D in persons 65 years of age and older, J Nutr
Finkelstein, Burnett-Bowie, Leder, Hypogonadism with Estrogen Removal (HER): effects of androgens and estrogens on body composition in young adult men
Fraser, Vitamin D-deficiency in Asia, J Steroid Biochem Mol Biol
Ginde, Liu, Camargo, Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004, Arch Intern Med
Giovannucci, Expanding roles of vitamin D, J Clin Endocrinol Metab
Giovannucci, Liu, Rimm, Prospective study of predictors of vitamin D status and cancer incidence and mortality in men, J Natl Cancer Inst
Gordon, Depeter, Feldman, Grace, Emans, Prevalence of vitamin D deficiency among healthy adolescents, Arch Pediatr Adolesc Med
Harris, Hughes, Seasonal changes in plasma 25-hydroxyvitamin D concentrations of young American black and white women, Am J Clin Nutr
Harris, Soteriades, Coolidge, Mudgal, Hughes, Vitamin D insufficiency and hyper-parathyroidism in a low income, multiracial, elderly population, J Clin Endocrinol Metab
Harris, Vitamin D and African Americans, J Nutr
Heaney, Dowell, Hale, Bendich, Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D, J Am Coll Nutr
Holick, Binkley, Bischoff-Ferrari, Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline, J Clin Endocrinol Metab
Holick, Resurrection of vitamin D deficiency and rickets, J Clin Invest
Holick, Siris, Binkley, Prevalence of vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy, J Clin Endocrinol Metab
Holick, Vitamin D deficiency, N Engl J Med
Kennel, Drake, Hurley, Vitamin D deficiency in adults: when to test and how to treat, Mayo Clin Proc
Kumar, Vitamin D and calcium transport, Kidney Int
Liu, Meigs, Pittas, Predicted 25-hydroxyvitamin D score and incident type 2 diabetes in the Framingham Offspring Study, Am J Clin Nutr
Looker, Dawson-Hughes, Calvo, Gunter, Sayhoun, Serum 25-hydroxyvitamin D status of adolescents and adults in two seasonal subpopulations from NHANES III, Bone
Looker, Johnson, Lacher, Pfeiffer, Schleicher et al., Vitamin D status: United States, 2001-2006, NCHS Data Brief
Manson, Bassuk, Lee, The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease, Contemp Clin Trials
Nesby, Dell, Scanlon, Cogswell, Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994, Am J Clin Nutr
Pappa, Gordon, Saslowsky, Vitamin D status in children and young adults with inflammatory bowel disease, Pediatrics
Priemel, Von Domarus, Klatte, Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients, J Bone Miner Res
Tangpricha, Pearce, Chen, Holick, Vitamin D insufficiency among free-living healthy adults, Am J Med
Thomas, Thadhani, Hypovitaminosis D in medical inpatients, N Engl J Med
Wortsman, Matsuoka, Chen, Lu, Holick, Decreased bioavailability of vitamin D in obesity, Am J Clin Nutr
Yetley, Assessing the vitamin D status of the US population, Am J Clin Nutr
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