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All Studies   Meta Analysis    Recent:   

Association of vitamin D status with severity of COVID-19

Kumar et al., Journal of Cardiovascular Disease Research, 12:6
Jun 2021  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now with p < 0.00000000001 from 121 studies, recognized in 9 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,300+ studies for 75 treatments. c19early.org
Analysis of 50 COVID-19 hospitalized patients, showing lower vitamin D levels associated with COVID-19 severity.
Kumar et al., 30 Jun 2021, retrospective, India, peer-reviewed, 4 authors.
This PaperVitamin DAll
ASSOCIATION OF VITAMIN D STATUS WITH SEVERITY OF COVID 19
Dr Manoj Kumar, Vidyasagar Ram, Pankaj Kumar, Shushil Kumar
Background:The present study was undertaken for assessing the association of serum vitamin D level with severity grading in COVID 19 RT-PCR positive patients. Materials & methods: 50 Patients diagnosed to have COVID 19 infection above age of 18 years admitted in COVID positive ward and COVID positive ICU were enrolled. Complete demographic and clinical details of all the patients were recorded. Serum vitamin D levels were assessed using auto-analyser and were correlated with severity of COVID-19. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. Results:Mean serum vitamin D levels among patients with mild, moderate, severe and critically ill COVID-19 was 33.4 ng/mL, 28.2 ng/mL, 23.2 ng/mL and 19.5 ng/mL respectively. Significant results were obtained while comparing mean serum Vitamin D levels among different severity of COVID-19. Conclusion:The overlap in the vitamin D associated biological pathways with the dysregulation reported to drive COVID-19 outcomes warrants further investigation, as does the role that vitamin D levels at time of presentation of COVID-19 may have as predictive biomarkers of disease severity.
References
Abdulateef, Rahman, Salih, Osman, Mahmood, COVID-19 severity in relation to sociodemographics and vitamin D use, Open Medicine
Alsafar, Grant, Hijazi, Uddin, Alkaabi et al., COVID-19 Disease Severity and Death in Relation to Vitamin D Status among SARS-CoV-2-Positive UAE Residents, Nutrients
Angelidi, Belanger, Lorinsky, Karamanis, Chamorro-Pareja et al., Vitamin D Status Is Associated With In-Hospital Mortality and Mechanical Ventilation: A Cohort of COVID-19 Hospitalized Patients, Mayo Clin Proc
Butler-Laporte, Nakanishi, Mooser, Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study, PLoS Med
Campi, Gennari, Merlotti, Vitamin D and COVID-19 severity and related mortality: a prospective study in Italy, BMC Infectious Diseases
Cereda, Bogliolo, Klersy, Lobascio, Vitamin D 25OH deficiency in COVID-19 patients admitted to a tertiary referral hospital, ClinNutr
Demir, Demir, Aygun, Vitamin D deficiency is associated with COVID-19 positivity and severity of the disease, J Med Virol
Ilie, Stefanescu, Smith, The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality, Aging ClinExp Res
Smet, Smet, Herroelen, Gryspeerdt, Martens, Serum 25(OH)D Level on Hospital Admission Associated With COVID-19 Stage and Mortality, Am J ClinPathol
Teshome, Adane, Girma, Mekonnen, The Impact of Vitamin D Level on COVID-19 Infection: Systematic Review and Meta-Analysis, Front Public Health
Wang, Joshi, Association of vitamin D deficiency with COVID-19 infection severity: Systematic review and meta-analysis, Clinical Endocrinology
Ye, Tang, Liao, Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity?-A Case-Control Study, J Am CollNutr
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