ASSOCIATION OF VITAMIN D STATUS WITH SEVERITY OF COVID 19
Dr Manoj Kumar, Vidyasagar Ram, Pankaj Kumar, Shushil Kumar
Background:The present study was undertaken for assessing the association of serum vitamin D level with severity grading in COVID 19 RT-PCR positive patients. Materials & methods: 50 Patients diagnosed to have COVID 19 infection above age of 18 years admitted in COVID positive ward and COVID positive ICU were enrolled. Complete demographic and clinical details of all the patients were recorded. Serum vitamin D levels were assessed using auto-analyser and were correlated with severity of COVID-19. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. Results:Mean serum vitamin D levels among patients with mild, moderate, severe and critically ill COVID-19 was 33.4 ng/mL, 28.2 ng/mL, 23.2 ng/mL and 19.5 ng/mL respectively. Significant results were obtained while comparing mean serum Vitamin D levels among different severity of COVID-19. Conclusion:The overlap in the vitamin D associated biological pathways with the dysregulation reported to drive COVID-19 outcomes warrants further investigation, as does the role that vitamin D levels at time of presentation of COVID-19 may have as predictive biomarkers of disease severity.
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