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Zinc deficiency is a potential risk factor for COVID-19 progression to pneumonia requiring oxygen therapy

Fujita et al., Journal of Infection and Chemotherapy, doi:10.1016/j.jiac.2024.03.007
Mar 2024  
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Oxygen therapy 86% Improvement Relative Risk Zinc for COVID-19  Fujita et al.  Sufficiency Are zinc levels associated with COVID-19 outcomes? Retrospective study in Japan (March 2020 - April 2021) Lower need for oxygen therapy with higher zinc levels (p=0.0074) c19early.org Fujita et al., J. Infection and Chemot.., Mar 2024 Favorszinc Favorscontrol 0 0.5 1 1.5 2+
Zinc for COVID-19
2nd treatment shown to reduce risk in July 2020, now with p = 0.00000032 from 46 studies, recognized in 17 countries.
No treatment is 100% effective. Protocols combine treatments.
5,300+ studies for 116 treatments. c19early.org
Retrospective 60 hospitalized COVID-19 patients in Japan showing higher risk of progression to pneumonia requiring oxygen therapy with zinc deficiency at the time of diagnosis.
risk of oxygen therapy, 86.3% lower, OR 0.14, p = 0.007, cutoff 60μg/dL, adjusted per study, inverted to make OR<1 favor high zinc levels (≥60μg/dL), multivariable, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Fujita et al., 8 Mar 2024, retrospective, Japan, peer-reviewed, 6 authors, study period 31 March, 2020 - 30 April, 2021.
This PaperZincAll
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