Scientific Opinion on the substantiation of health claims related to folate and blood formation (ID 79), homocysteine metabolism (ID 80), energy-yielding metabolism (ID 90), function of the immune system (ID 91), function of blood vessels (ID 94, 175, 192
Jean-Louis Bresson, Albert Flynn, Marina Heinonen, Karin Hulshof, Hannu Korhonen, Pagona Lagiou, Martinus Løvik, Rosangela Marchelli, Ambroise Martin, Bevan Moseley, Hildegard Przyrembel, Seppo Salminen, J J ) Strain, Stephan Strobel, Inge Tetens, Henk Van Den Berg, Hendrik Van Loveren, Hans Verhagen
EFSA Journal, doi:10.2903/j.efsa.2009.1213
and maternal tissue growth during pregnancy
INFORMATION AS PROVIDED IN THE CONSOLIDATED LIST The consolidated list of health claims pursuant to Article 13 of Regulation (EC) No 1924/2006 3 submitted by Member States contains main entry claims with corresponding conditions of use and literature from similar health claims. The information provided in the consolidated list for the health claims subject to this opinion is tabulated in Appendix C.
APPENDICES APPENDIX A BACKGROUND AND TERMS OF REFERENCE AS PROVIDED BY THE EUROPEAN COMMISSION The Regulation 1924/2006 on nutrition and health claims made on foods 6 (hereinafter "the Regulation") entered into force on 19 th January 2007. Article 13 of the Regulation foresees that the Commission shall adopt a Community list of permitted health claims other than those referring to the reduction of disease risk and to children's development and health. This Community list shall be adopted through the Regulatory Committee procedure and following consultation of the European Food Safety Authority (EFSA). Health claims are defined as "any claim that states, suggests or implies that a relationship exists between a food category, a food or one of its constituents and health". In accordance with Article 13 (1) health claims other than those referring to the reduction of disease risk and to children's development and health are health claims describing or referring to: a) the role of a nutrient or other substance in growth, development and the functions of the body;..
References
Bailey, Gregory, Folate. In: Present knowledge in nutrition
Chitambar, Ac, Nutritional aspects of some hematological disease, Modern Nutrition in Health and Disease
Courtemanche, Elson-Schwab, Mashiyama, Kerry, Ames, Folate deficiency inhibits the proliferation of primary human CD8+ T lymphocytes in vitro, J Immunol
De Bree, Van Mierlo, Draijer, Folic acid improves vascular reactivity in humans: a meta-analysis of randomized controlled trials, Am. J. Clin. Nutr
Mcpartlin, Folic acid, Encyclopedia of Human Nutrition
Miller, Homocysteine. In: Encyclopedia of Human Nutrition
Shirodaria, Antoniades, Lee, Jackson, Robson et al., Global Improvement of Vascular Function and Redox State With Low-Dose Folic Acid: Implications for Folate Therapy in Patients With Coronary Artery Disease, Circulation
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