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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Mortality 75% Improvement Relative Risk Vitamin D for COVID-19  Davran et al.  Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Retrospective 94 patients in Turkey Lower mortality with higher vitamin D levels (p=0.017) c19early.org Davran et al., Konuralp Tıp Dergisi, Mar 2023 Favors vitamin D Favors control

Relationship between vitamin D level and clinical status in COVID-19 patients

Davran et al., Konuralp Tıp Dergisi, doi:10.18521/ktd.1134319
Mar 2023  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now known with p < 0.00000000001 from 120 studies, recognized in 8 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,100+ studies for 60+ treatments. c19early.org
Retrospective 47 outpatient and 47 hospitalized COVID-19 patients in Turkey, showing higher mortality with vitamin D deficiency in unadjusted results.
This is the 165th of 196 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 11,637 vigintillion).
risk of death, 75.4% lower, RR 0.25, p = 0.02, high D levels (≥10ng/ml) 4 of 63 (6.3%), low D levels (<10ng/ml) 8 of 31 (25.8%), NNT 5.1.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Davran et al., 15 Mar 2023, retrospective, Turkey, peer-reviewed, mean age 53.6, 9 authors. Contact: ceyhanhacioglu@duzce.edu.tr, konuralptipdergi@duzce.edu.tr, konuralptipdergisi@gmail.com.
This PaperVitamin DAll
Relationship between vitamin D level and clinical status in COVID-19 patients
Fatih Davran, Ceyhan Hacioğlu, Pelin Kamuran Duran, Elif Nisa Unlu, Banu Hümeyra Keskin, Eda Kayabaşi, Elif Eşcan, Şengül Cangür, Cihadiye Öztürk
Konuralp Tıp Dergisi, doi:10.18521/ktd.1134319
Objective: Vitamin D plays an important role in maintaining the integrity of mucosal barriers and in natural and acquired immunity. In the COVID-19 pandemic, the strength of personal immunity is very important in the course of the disease, despite the presence of variants of the virus or vaccination status. Method: In this study, we investigated the relationship between the clinical course and vitamin D levels of outpatient and inpatient follow-up patients admitted to our hospital due to COVID-19. A total of 94 patients, 47 outpatients and 47 inpatients, were included in the study. Results: The mean age and gender distributions of both groups were similar. Vitamin D levels were found to be normal in only 7 of 94 patients who were followed up in our hospital due to COVID-19. Patients with vitamin D levels ≥30 were significantly lower than those with "<10" and "10-29.9" (p<0.01 for each). Hospitalized patients (71%) with vitamin D levels <10 were significantly higher than those (0%) with vitamin D levels ≥30. Additionally, the outpatients (29%) with vitamin D levels <10 were significantly lower than those (100%) with vitamin D levels ≥30. Conclusion: The data showed that vitamin D deficiency may be associated with the severe clinical course of COVID-19, even in patients without comorbidities, and may also be one of the predisposing factors resulting in death in COVID-19. As a result, vitamin D levels in COVID-19 patients may be important for the course of the disease.
References
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