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0 0.5 1 1.5 2+ Mortality 75% Improvement Relative Risk Davran et al. Vitamin D for COVID-19 Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Retrospective 94 patients in Turkey Lower mortality with higher vitamin D levels (p=0.017) Davran et al., Konuralp Tıp Dergisi, doi:10.18521/ktd.1134319 Favors vitamin D Favors control

Relationship between vitamin D level and clinical status in COVID-19 patients

Davran et al., Konuralp Tıp Dergisi, doi:10.18521/ktd.1134319
Davran et al., Relationship between vitamin D level and clinical status in COVID-19 patients, Konuralp Tıp Dergisi, doi:10.18521/ktd.1134319
Mar 2023   Source   PDF  
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Retrospective 47 outpatient and 47 hospitalized COVID-19 patients in Turkey, showing higher mortality with vitamin D deficiency in unadjusted results.
This is the 162nd of 177 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 26 vigintillion).
risk of death, 75.4% lower, RR 0.25, p = 0.02, high D levels (≥10ng/ml) 4 of 63 (6.3%), low D levels (<10ng/ml) 8 of 31 (25.8%), NNT 5.1.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Davran et al., 15 Mar 2023, retrospective, Turkey, peer-reviewed, mean age 53.6, 9 authors.
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This PaperVitamin DAll
Relationship between vitamin D level and clinical status in COVID-19 patients
Fatih Davran, Ceyhan Hacioğlu, Pelin Kamuran Duran, Elif Nisa Unlu, Banu Hümeyra Keskin, Eda Kayabaşi, Elif Eşcan, Şengül Cangür, Cihadiye Öztürk
Konuralp Tıp Dergisi, doi:10.18521/ktd.1134319
Objective: Vitamin D plays an important role in maintaining the integrity of mucosal barriers and in natural and acquired immunity. In the COVID-19 pandemic, the strength of personal immunity is very important in the course of the disease, despite the presence of variants of the virus or vaccination status. Method: In this study, we investigated the relationship between the clinical course and vitamin D levels of outpatient and inpatient follow-up patients admitted to our hospital due to COVID-19. A total of 94 patients, 47 outpatients and 47 inpatients, were included in the study. Results: The mean age and gender distributions of both groups were similar. Vitamin D levels were found to be normal in only 7 of 94 patients who were followed up in our hospital due to COVID-19. Patients with vitamin D levels ≥30 were significantly lower than those with "<10" and "10-29.9" (p<0.01 for each). Hospitalized patients (71%) with vitamin D levels <10 were significantly higher than those (0%) with vitamin D levels ≥30. Additionally, the outpatients (29%) with vitamin D levels <10 were significantly lower than those (100%) with vitamin D levels ≥30. Conclusion: The data showed that vitamin D deficiency may be associated with the severe clinical course of COVID-19, even in patients without comorbidities, and may also be one of the predisposing factors resulting in death in COVID-19. As a result, vitamin D levels in COVID-19 patients may be important for the course of the disease.
Ali, Role of vitamin D in preventing of COVID-19 infection, progression and severity, J Infect Public Health
Alshishtawy, Vitamin D Deficiency: This clandestine endemic disease is veiled no more, Sultan Qaboos Univ Med J
Beard, Bearden, Striker, Vitamin D and the anti-viral state, J Clin Virol
Christakos, Ajibade, Dhawan, Fechner, Mady, Vitamin D: metabolism, Endocrinol Metab Clin North Am
Grant, Lahore, Mcdonnell, Baggerly, French et al., Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths, Nutrients
Hewison, Vitamin D and innate and adaptive immunity, Vitam Horm
Kim, Lee, Yang, Lee, Effenberger et al., Immunopathogenesis and treatment of cytokine storm in COVID-19, Theranostics
Kumar, Rathi, Haq, Wimalawansa, Sharma, Putative roles of vitamin D in modulating immune response and immunopathology associated with COVID-19, Virus Res
Merzon, Tworowski, Gorohovski, Vinker, Cohen et al., Low plasma 25(OH) vitamin D level is associated with increased risk of COVID-19 infection: an Israeli population-based study, FEBS J
Munshi, Hussein, Toraih, Elshazli, Jardak et al., Vitamin D insufficiency as a potential culprit in critical COVID-19 patients, J Med Virol
Pereira, Damascena, Azevedo, De Almeida Oliveira, Da et al., Vitamin D deficiency aggravates COVID-19: systematic review and meta-analysis, Crit Rev Food Sci Nutr
Rondanelli, Miccono, Lamburghini, Avanzato, Riva et al., Self-Care for Common Colds: The Pivotal Role of Vitamin D, Vitamin C, Zinc, and Echinacea in Three Main Immune Interactive Clusters (Physical Barriers, Innate and Adaptive Immunity) Involved during an Episode of Common Colds-Practical Advice on Dosages and on the Time to Take These Nutrients/Botanicals in order to Prevent or Treat Common Colds, Evid Based Complement Alternat Med
Schmid, Walther, Natural vitamin D content in animal products, Adv Nutr
Schwalfenberg, A review of the critical role of vitamin D in the functioning of the immune system and the clinical implications of vitamin D deficiency, Mol Nutr Food Res
Simpson, Kay, Abbara, Bhalla, Chung et al., Radiological Society of North America Expert Consensus Document on Reporting Chest CT Findings Related to COVID-19: Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA, Radiol Cardiothorac Imaging
Smith, Grenier, Batte, Spieler, A Characteristic Chest Radiographic Pattern in the Setting of the COVID-19 Pandemic, Radiol Cardiothorac Imaging
Tsujino, Ushikoshi-Nakayama, Yamazaki, Matsumoto, Saito, Pulmonary activation of vitamin D3 and preventive effect against interstitial pneumonia, J Clin Bioc hem Nutr
Wacker, Holick, Sunlight and Vitamin D: A global perspective for health, Dermatoendocrinol
Yu, Zhu, Zhang, Han, A Familial Cluster of Infection Associated with the 2019 Novel Coronavirus Indicating Possible Person-to-Person Transmission During the Incubation Period, J Infect Dis
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