Statistically significant lower risk is seen for mortality, recovery, and cases. 8 studies from 7 independent teams in 4 countries show significant improvements.
Meta analysis using the most serious outcome reported shows 39% [23‑52%] lower risk. Results are similar for peer-reviewed studies and better for Randomized Controlled Trials. Early treatment is more effective than late treatment.
Results are very robust — in exclusion sensitivity analysis 8 of 15 studies must be excluded to avoid finding statistically significant efficacy in pooled analysis.
No treatment or intervention is 100% effective. All practical, effective, and safe means should be used based on risk/benefit analysis. Multiple treatments are typically used in combination, and other treatments may be more effective.
All data to reproduce this paper and sources are in the appendix.
Covid Analysis et al., Oct 2024, preprint, 1 author.
