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All Studies   Meta Analysis    Recent:   

Exercise for COVID-19: real-time meta analysis of 67 studies

Covid Analysis
Oct 2024  
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Exercise for COVID-19
9th treatment shown to reduce risk in October 2020
 
*, now with p < 0.00000000001 from 67 studies.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,800+ studies for 95 treatments. c19early.org
Statistically significant lower risk is seen for mortality, ventilation, ICU admission, hospitalization, progression, recovery, and cases. 52 studies from 52 independent teams in 24 countries show significant improvements.
Meta analysis using the most serious outcome reported shows 39% [33‑44%] lower risk. Results are similar for higher quality and peer-reviewed studies.
Results are very robust — in exclusion sensitivity analysis 55 of 67 studies must be excluded to avoid finding statistically significant efficacy in pooled analysis.
Results are consistent with the overall risk of all cause mortality based on cardiorespiratory fitness — Laukkanen show RR 0.55 [0.50-0.61] for the top vs. bottom tertiles.
Most studies analyze activity levels before infection, comparing regular/moderate exercise and lower/no exercise. Risk may increase with more extreme activity levels. Exercise may also be beneficial after infection. One study shows lower COVID-19 mortality with exercise during hospitalization2.
No treatment or intervention is 100% effective. All practical, effective, and safe means should be used based on risk/benefit analysis.
All data to reproduce this paper and sources are in the appendix. 6 other meta analyses show significant improvements with exercise for mortality3-7, ICU admission3, hospitalization3,4,7,8, severity4-6, and cases4.
6 meta analyses show significant improvements with exercise for mortality1-5, ICU admission1, hospitalization1,2,5,6, severity2-4, and cases2.
Covid Analysis et al., Oct 2024, preprint, 1 author.
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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