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Serum Levels of Vitamin C and Vitamin D in a Cohort of Critically Ill COVID-19 Patients of a North American Community Hospital Intensive Care Unit in May 2020: A Pilot Study

Arvinte et al., Med. Drug Discov, doi:10.1016/j.medidd.2020.100064
Sep 2020  
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Vitamin C for COVID-19
6th treatment shown to reduce risk in September 2020
 
*, now with p = 0.000000028 from 72 studies, recognized in 12 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,800+ studies for 95 treatments. c19early.org
Pilot study with 21 ICU patients finding low serum levels of vitamin C and vitamin D in most patients. Older age and low vitamin C level appeared to be co-dependent risk factors for mortality.
This study is excluded in the after exclusion results of meta analysis: very late stage, ICU patients.
Arvinte et al., 8 Sep 2020, peer-reviewed, 3 authors.
This PaperVitamin CAll
Serum Levels of Vitamin C and Vitamin D in a Cohort of Critically Ill COVID-19 Patients of a North American Community Hospital Intensive Care Unit in May 2020: A Pilot Study
MD a, ⁎ Cristian Arvinte, PhD Maharaj Singh, MD, FCCP Paul E Marik
Medicine in Drug Discovery, doi:10.1016/j.medidd.2020.100064
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre -including this research content -immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
Conflict of Interest The authors of this paper have had no conflicts of interest in conducting and publishing this research. Ethical Approval and Informed Consent The work involved in conducting our research has followed standard medical ethical rules and regulations.
References
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Grant, Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths, Nutrients
Long, Dosing matters! Vitamin C in critical illness, Crit Care Med
Marik, Vitamin C: an essential "stress hormone" during sepsis, J Thorac Dis
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