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All Studies   Meta Analysis    Recent:   

Povidone Iodine (PVP-I) Oro-Nasal Spray: An Effective Shield for COVID-19 Protection for Health Care Worker (HCW), for all

Arefin, M., Indian Journal of Otolaryngology and Head & Neck Surgery, doi:10.1007/s12070-021-02525-9
Apr 2021  
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PVP-I for COVID-19
13th treatment shown to reduce risk in February 2021
 
*, now known with p = 0.000000037 from 20 studies.
Lower risk for mortality, cases, and viral clearance.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,900+ studies for 60+ treatments. c19early.org
Report on clinical experience with prophylactic use of PVP-I for COVID-19 in a very high risk environment with no infections, review of the use of PVP-I for the prevention of respiratory infections, and recommendations for use with COVID-19.
Arefin et al., 8 Apr 2021, peer-reviewed, 1 author.
This PaperPovidone-Iod..All
Povidone Iodine (PVP-I) Oro-Nasal Spray: An Effective Shield for COVID-19 Protection for Health Care Worker (HCW), for all
Mostafa Kamal
Indian Journal of Otolaryngology and Head & Neck Surgery, doi:10.1007/s12070-021-02525-9
SARS-CoV-2 or novel coronavirus enters in human body through nose and mouth, stays there for a while. Then binds with ACE2 receptor, enters inside cell, multiply there and manifests. Again, Polyvinyl Pyrrolidone or Povidone Iodine (PVP-I) is a strong microbicidal agent having 99.99% virucidal efficacy in its only 0.23% concentration, irrespective of all known viruses, even in SARS-CoV-2 (in vitro). An oro-nasal spray is designed to apply the PVP-I in nose and oral cavity to gain a protective layer or coating over nasal and oral mucosa, so that SARS-CoV-2 can't bind with the ACE-2 receptor and prevent their entry inside. So, it will be effective for prevention of COVID-19. Moreover, as PVP-I has the ability for destruction of SARS-CoV-2, transmission of SARS-CoV-2 from patient will be reduced also. Thus PVP-I oro-nasal spray can act as an effective shield for COVID-19 protection for healthcare workers, for all.
Conflict of interest There is no competing interest. Ethical Approval Not applicable. Informed Consent All of the patients or their attendants gave written informed consent to participate in the study willingly without any prejudice.
References
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Arefin, Islam, Shawrave, Rahman, The Role of Povidone Iodine Mouthwash & Nasal Spray or Drop or Inhalation for Protection (Prevention & Treatment) of Health Care Professionals as Well as Patients and Reduction of Cross Infection during Current COVID-19 Pandemic Situation
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