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Therapeutic effect of Vitamin A on severe COVID-19 patients

Al-Sumiadai et al., EurAsian Journal of Biosciences, 14:7347-7350
Dec 2020  
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Mortality 86% Improvement Relative Risk Vitamin A  Al-Sumiadai et al.  EARLY TREATMENT Is early treatment with vitamin A beneficial for COVID-19? Retrospective 140 patients in Iraq Lower mortality with vitamin A (p=0.0024) c19early.org Al-Sumiadai et al., EurAsian J. Biosci.., Dec 2020 Favorsvitamin A Favorscontrol 0 0.5 1 1.5 2+
Vitamin A for COVID-19
42nd treatment shown to reduce risk in June 2023, now with p = 0.021 from 14 studies.
Lower risk for recovery and cases.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 109 treatments. c19early.org
Retrospective 70 severe condition patients treated with vitamin A (200,000IU for two days), salbutamol, and budesonide, and 70 patients not treated with vitamin A, showing significantly lower mortality with the addition of vitamin A.
This study is excluded in the after exclusion results of meta analysis: minimal details of groups provided.
risk of death, 85.7% lower, RR 0.14, p = 0.002, treatment 2 of 70 (2.9%), control 14 of 70 (20.0%), NNT 5.8.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Al-Sumiadai et al., 31 Dec 2020, retrospective, Iraq, peer-reviewed, 3 authors.
This PaperVitamin AAll
Therapeutic effect of Vitamin A on severe COVID-19 patients
Mahmood M Al-Sumiadai, Hazim Ghazzay, Wisam Zabin, Saleh Al-Dulaimy
Objective: To find the effect of administration of vitamin A on patients with severe COVID-19. Material and Methods: A cross-sectional and retrospective study was done on two groups of patients with severe COVID-19 in isolation centers in Anbar governorate. The first group was patients with severe COVID-19 given two doses of vitamin A (200,000 I.U.) for two days from the first day of admission and three doses per day of salbutamol and budesonide nebulizers.. Data about the respiratory rate and SPO2 were collected after 48 and 96 hours from the administration in addition to the death rate among those patients. In a second group, the data was collected from files of patients with severe COVID-19 previously admitted to isolated centers and not receiving vitamin A. Results: A significant improvement in SPO2 and respiratory rate among severe COVID-19 patients given vitamin A as compared to those not given vitamin A. A lower death rate was recorded among severe COVID-19 patients who received vitamin A from those not received. Conclusions; A great benefit of the using of vitamin A in patients with severe COVID-19. Adding vitamin A to the regime COVID-19 therapy is recommended.
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