Vitamin D, Calcium and Phosphorus Status Involvement during COVID-19 Infection
Abdallah Eltoum Ali, Mohamed Fathy Seyyed Ahmed, Somia Mohammed Suliman, Ibrahim Ahamed Ali Karti, Haidar Eltayeb Saleh
Asian Journal of Research in Biochemistry, doi:10.9734/ajrb/2022/v11i2214
Background: COVID-19 is associated with a weak immune system in the human body. Vitamin D plays a role in the body's immune system and is known to enhance the function of immune cells. In this case, vitamin D inhibits some of the inflammation that can make COVID-19 more severe. The is study aims to determine the serum levels of vitamin D, calcium, and phosphorus in COVID-19 patients. Methods: This was a cross sectional study conducted during the period from January 2021 to July
COMPETING INTERESTS
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DOI record:
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"abstract": "<jats:p>Background: COVID-19 is associated with a weak immune system in the human body. Vitamin D plays a role in the body’s immune system and is known to enhance the function of immune cells. In this case, vitamin D inhibits some of the inflammation that can make COVID-19 more severe. The is study aims to determine the serum levels of vitamin D, calcium, and phosphorus in COVID-19 patients.
\nMethods: This was a cross sectional study conducted during the period from January 2021 to July 2021. 50 COVID-19 patients as a case study and 50 healthy individuals as a control group were included in this study. Blood samples were collected from the study group and measured for vitamin D using Enzyme-linked immunosorbent assay (ELISA) technique. Calcium and phosphate were measured by the Cobas 6000 fully automated analyzer (Roche, Germany).
\nResults: The study result showed that in COVID-19 patients, vitamin D (27 ± 5 ng/mL), p-value = 0.000, and calcium (10.2 ± 4 mg/dL), p-value = 0.000, in comparison with control. There was a correlation between vitamin D (r = -.771; p =.000) and calcium (r = -.752; p =.000) and the severity of disease.
\nConclusions: According to our research, vitamin D deficiency may increase the risk of developing COVID-19 and the risk of developing severe illnesses.</jats:p>",
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