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Cardiovascular complications are the primary drivers of mortality in hospitalized patients with SARS-CoV-2 community-acquired pneumonia

Nov 2022  
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Mortality 28% Improvement Relative Risk Aspirin for COVID-19  Ali et al.  Prophylaxis Is prophylaxis with aspirin beneficial for COVID-19? Retrospective 1,645 patients in the USA Lower mortality with aspirin (not stat. sig., p=0.067) Ali et al., Chest, November 2022 Favorsaspirin Favorscontrol 0 0.5 1 1.5 2+
Retrospective 1,645 hospitalized patients in the USA, showing lower mortality with aspirin use, without statistical significance.
risk of death, 28.0% lower, HR 0.72, p = 0.07, treatment 481, control 1,164, Cox proportional hazards.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Ali et al., 19 Nov 2022, retrospective, USA, peer-reviewed, 8 authors. Contact:
This PaperAspirinAll
Cardiovascular Complications Are the Primary Drivers of Mortality in Hospitalized Patients With SARS-CoV-2 Community-Acquired Pneumonia
MD Ahmed Shebl Ali, MD. Daniya Sheikh, MPH Thomas R Chandler, MS MPH Stephen Furmanek, MD PhD Jiapeng Huang, MD, FACP Julio A Ramirez, DO, MSc, FIDSA Forest Arnold, MD Rodrigo Cavallazzi
Chest, doi:10.1016/j.chest.2022.11.013
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Author Contributions A.S. and D.S. contributed to writing and data interpretation. T.R.C. and S.F. contributed to writing and data analysis. J.H. contributed to writing and data interpretation. J.R. and R.C. contributed to study design, writing and data interpretation. F.A. contributed to data interpretation. R.C. takes the responsibility of the content of the manuscript including data and analysis. Financial/nonfinancial disclosures None J o u r n a l P r e -p r o o f
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