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0 0.5 1 1.5 2+ Mortality 96% Improvement Relative Risk Severe case 93% Al-Haidari et al. Nigella Sativa for COVID-19 RCT EARLY Is early treatment with nigella sativa beneficial for COVID-19? RCT 419 patients in Iraq Lower mortality (p=0.0013) and severe cases (p<0.0001) Al-Haidari et al., Indian J. Forensic Medicine & Toxicology, 15:3 Favors nigella sativa Favors control
Clinical Trial of Black Seeds Against COVID – 19 in Kirkuk City / Iraq
Al-Haidari et al., Indian Journal of Forensic Medicine & Toxicology, 15:3 (date from earlier preprint)
Al-Haidari et al., Clinical Trial of Black Seeds Against COVID – 19 in Kirkuk City / Iraq, Indian Journal of Forensic Medicine & Toxicology, 15:3 (date from earlier preprint)
Jan 2021   Source   PDF  
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Open-label RCT with 419 patients in Iraq, 160 treated with Nigella Sativa, showing lower mortality and severe cases with treatment. Black seeds 40mg/kg orally once daily for 14 days.
risk of death, 95.8% lower, RR 0.04, p = 0.001, treatment 0 of 160 (0.0%), control 14 of 259 (5.4%), NNT 18, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of severe case, 92.6% lower, RR 0.07, p < 0.001, treatment 2 of 160 (1.2%), control 44 of 259 (17.0%), NNT 6.4.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Al-Haidari et al., 31 Jan 2021, Randomized Controlled Trial, Iraq, peer-reviewed, 3 authors.
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Abstract: See discussions, stats, and author profiles for this publication at: Clinical Trial of Black Seeds Against COVID -19 in Kirkuk City/ Iraq Article in Indian Journal of Forensic Medicine & Toxicology · January 2021 CITATIONS READS 0 108 3 authors, including: Tunjai Namiq Faiq Ozdan Akram Ghareeb Kirkuk Health Directorate Northern Technical University 8 PUBLICATIONS 1 CITATION 17 PUBLICATIONS 7 CITATIONS SEE PROFILE All content following this page was uploaded by Tunjai Namiq Faiq on 05 June 2021. The user has requested enhancement of the SEE PROFILE Indian Journal of Forensic Medicine & Toxicology, July-September 2021, Vol. 15, No. 3 3393 Clinical Trial of Black Seeds Against COVID – 19 in Kirkuk City/ Iraq Kadhim Ali Abbas Al-Haidari1, TunjaiNamiq Faiq2 , OzdanAkram Ghareeb3 1 Family Physician inKirkuk Rehabilitation Center, Kirkuk Health Directorate, Iraq, 2Consultant Otolaryngologist in Kirkuk General Hospital, Kirkuk Health Directorate, Iraq, 3Assistant Lecturer in Department of Community Health Techniques, Kirkuk Technical Institute Abstract In order to cope with Coronavirus Disease 2019 (COVID-19) pandemic, there is an urgent need for effective prevention and control measures. This study aims to explore the positive action of black seeds (BS) against COVID-19 in patients involved in the trail. It is a descriptive, comparative, and open-label study. In our study, (419) participants were divided into two groups.The studied participants included patients which received standard care treatment as a control group (CON) , while the (BS) group were patients received black seeds at a 40 mg/kg dose orally, once daily for 14 days plus standard protocol of treatment. The evidence of BS efficacy was obvious in the severity and outcome of infection with covid-19. A significantly higher severity of infection among control group 44 (17.0%) than the black seed group were noticed; the control group also showed 14 deaths (5.4%), while there were no deaths in black seeds group (0.0%). Thus, we can conclude that black seed is very effective in reducing the severity of covid-19 and preventing death in infected patients. Key words : Pandemic disease, COVID-19, Infection,medicinal plant, , Black seeds
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