Clinical Trial of Black Seeds Against COVID – 19 in Kirkuk City / Iraq
Al-Haidari et al., Indian Journal of Forensic Medicine & Toxicology, 15:3 (date from earlier preprint)
Al-Haidari et al., Clinical Trial of Black Seeds Against COVID – 19 in Kirkuk City / Iraq, Indian Journal of Forensic Medicine & Toxicology, 15:3 (date from earlier preprint)
Open-label RCT with 419 patients in Iraq, 160 treated with Nigella Sativa, showing lower mortality and severe cases with treatment. Black seeds 40mg/kg orally once daily for 14 days.
risk of death, 95.8% lower, RR 0.04, p = 0.001, treatment 0 of 160 (0.0%), control 14 of 259 (5.4%), NNT 18, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
risk of severe case, 92.6% lower, RR 0.07, p < 0.001, treatment 2 of 160 (1.2%), control 44 of 259 (17.0%), NNT 6.4.
Abstract: See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/352134969
Clinical Trial of Black Seeds Against COVID -19 in Kirkuk City/ Iraq
Article in Indian Journal of Forensic Medicine & Toxicology · January 2021
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Indian Journal of Forensic Medicine & Toxicology, July-September 2021, Vol. 15, No. 3
3393
Clinical Trial of Black Seeds Against COVID – 19 in Kirkuk
City/ Iraq
Kadhim Ali Abbas Al-Haidari1, TunjaiNamiq Faiq2 , OzdanAkram Ghareeb3
1
Family Physician inKirkuk Rehabilitation Center, Kirkuk Health Directorate, Iraq, 2Consultant Otolaryngologist
in Kirkuk General Hospital, Kirkuk Health Directorate, Iraq, 3Assistant Lecturer in Department of Community
Health Techniques, Kirkuk Technical Institute
Abstract
In order to cope with Coronavirus Disease 2019 (COVID-19) pandemic, there is an urgent need for effective
prevention and control measures. This study aims to explore the positive action of black seeds (BS) against
COVID-19 in patients involved in the trail. It is a descriptive, comparative, and open-label study. In our
study, (419) participants were divided into two groups.The studied participants included patients which
received standard care treatment as a control group (CON) , while the (BS) group were patients received
black seeds at a 40 mg/kg dose orally, once daily for 14 days plus standard protocol of treatment. The
evidence of BS efficacy was obvious in the severity and outcome of infection with covid-19. A significantly
higher severity of infection among control group 44 (17.0%) than the black seed group were noticed; the
control group also showed 14 deaths (5.4%), while there were no deaths in black seeds group (0.0%). Thus,
we can conclude that black seed is very effective in reducing the severity of covid-19 and preventing death
in infected patients.
Key words : Pandemic disease, COVID-19, Infection,medicinal plant, , Black seeds
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