Global trends in clinical trials of ivermectin for COVID-19—Part 2

Yagisawa et al., The Japanese Journal of Antibiotics, doi:10.11553/antibiotics.77.1_45, Mar 2024

Ivermectin for COVID-19

4th treatment shown to reduce risk in August 2020, now with p < 0.0000000001 from 106 studies, recognized in 24 countries.

No treatment is 100% effective.
Protocols combine treatments.

Review of global trends in clinical trials of ivermectin for COVID-19. The review summarizes and analyzes the results of trials to date. Authors report that 27 systematic reviews and meta-analyses have been conducted, with 15 demonstrating ivermectin efficacy. Authors conclude that COVID-19 has changed over time, limiting standard meta-analysis without addressing the changes, unlike other chronic diseases. Several important trials were found to have serious errors or protocol violations.
Reviews covering ivermectin for COVID-19 include1-51.
Yagisawa et al., 25 Mar 2024, peer-reviewed, 4 authors.
DOI record: { "DOI": "10.11553/antibiotics.77.1_45", "ISSN": [ "03682781", "03682781", "21865477" ], "URL": "https://doi.org/10.11553/antibiotics.77.1_45", "author": [ { "family": "Yagisawa, Ph.D.", "given": "Morimasa" }, { "family": "J. Foster, M.D.", "given": "Patrick" }, { "family": "Hanaki, Ph.D.", "given": "Hideaki" }, { "family": "Ōmura, Ph.D.", "given": "Satoshi" } ], "container-title": "The Japanese Journal of Antibiotics", "issued": { "date-parts": [ [ 2024, 3, 25 ] ] }, "language": "en", "number": "1", "page": "45-92", "publisher": "Japan Antibiotics Research Association", "title": "Global trends in clinical trials of ivermectin for COVID-19—Part 2", "volume": "77" }