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"author": "Chen",
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"author": "Lim",
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"DOI": "10.1038/s41579-022-00722-z",
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"author": "Maurya",
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"year": "2021"
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"DOI": "10.1016/j.ijid.2020.09.033",
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"author": "Moreno-P",
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"DOI": "10.3389/fimmu.2020.01239",
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"author": "Murck",
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"author": "Murtem",
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"issue": "3",
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"volume": "3",
"year": "2016"
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"DOI": "10.1080/07391102.2020.1777901",
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"author": "Murugan",
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"author": "Pocock",
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"article-title": "Phytochemical 6-Gingerol – a promising Drug of choice for COVID-19",
"author": "Rathinavel",
"first-page": "1482",
"issue": "4",
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"volume": "6",
"year": "2020"
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{
"DOI": "10.3390/ph15081013",
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