Vitamin D status in Covid-19 patients admitted to the critical care unit of an Eastern India hospital
Avijit Saha, Sangeeta Ghosh, Sandip Ghosh, Sanjay Vashistha, Shitama Aich, Tapas Kumar Sur
Exploratory Animal and Medical Research, doi:10.52635/eamr/13.1.16-21
The COVID-19 patients experienced acute respiratory distress during their SARS-CoV-2 infections. The present observational study was undertaken to find out the possible association between vitamin D and COVID-19 clinical severity in a tertiary care hospital from November 2021 to February 2022. Patients admitted to the hospital's Critical Care Unit (CCU) with SARS-CoV-2 illness were selected for blood vitamin D estimations. Patients' conditions were evaluated clinically and correlated with serum vitamin D levels. Out of a total of 97 COVID-19 patients selected, 64.9% were male. Clinically, 41.3% of patients had a severe COVID-19 infection, compared to a moderate infection incidence of 58.7%. Among them, 19.6% and 42.2% were found to be vitamin D deficient and vitamin D insufficient, respectively. Serum vitamin D was significantly (p<0.001) reduced with age (≤ ≤ ≤ ≤ ≤ 60 yrs vs. ≥ ≥ ≥ ≥ ≥ 60 yrs) and with disease severe (moderate vs. severe). The insufficiency/deficiency of vitamin D was higher among the aged acute respiratory-infected COVID-19 patients. Therefore, vitamin D deficiency may be one of the main causes of severe illness in SARS-CoV-2 patients.
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