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Vitamin D status in Covid-19 patients admitted to the critical care unit of an Eastern India hospital

Saha et al., Exploratory Animal and Medical Research, doi:10.52635/eamr/13.1.16-21
Jun 2023  
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Analysis of 97 COVID-19 CCU patients in India. Patients with severe COVID-19 had significantly lower vitamin D levels compared to those with moderate COVID-19. There was a significant correlation between lower vitamin D levels and more severe cases. 19.6% of patients were vitamin D deficient (<20 ng/ml) and 42.2% were vitamin D insufficient (20-30 ng/ml).
Saha et al., 30 Jun 2023, prospective, India, peer-reviewed, mean age 59.7, 6 authors, study period November 2021 - February 2022. Contact:
This PaperVitamin DAll
Vitamin D status in Covid-19 patients admitted to the critical care unit of an Eastern India hospital
Avijit Saha, Sangeeta Ghosh, Sandip Ghosh, Sanjay Vashistha, Shitama Aich, Tapas Kumar Sur
Exploratory Animal and Medical Research, doi:10.52635/eamr/13.1.16-21
The COVID-19 patients experienced acute respiratory distress during their SARS-CoV-2 infections. The present observational study was undertaken to find out the possible association between vitamin D and COVID-19 clinical severity in a tertiary care hospital from November 2021 to February 2022. Patients admitted to the hospital's Critical Care Unit (CCU) with SARS-CoV-2 illness were selected for blood vitamin D estimations. Patients' conditions were evaluated clinically and correlated with serum vitamin D levels. Out of a total of 97 COVID-19 patients selected, 64.9% were male. Clinically, 41.3% of patients had a severe COVID-19 infection, compared to a moderate infection incidence of 58.7%. Among them, 19.6% and 42.2% were found to be vitamin D deficient and vitamin D insufficient, respectively. Serum vitamin D was significantly (p<0.001) reduced with age (≤ ≤ ≤ ≤ ≤ 60 yrs vs. ≥ ≥ ≥ ≥ ≥ 60 yrs) and with disease severe (moderate vs. severe). The insufficiency/deficiency of vitamin D was higher among the aged acute respiratory-infected COVID-19 patients. Therefore, vitamin D deficiency may be one of the main causes of severe illness in SARS-CoV-2 patients.
Amrein, Scherkl, Hoffmann, Neuwersch-Sommeregger, Köstenberger et al., None
Aparna, Muthathal, Nongkynrih, Gupta, None
Cannell, Vieth, Willett, Zasloff, Hathcock, Vitamin D deficiency and co-morbidities in COVID-19 patients -A fatal relationship?, J Family Med Prim Care, doi:10.4103/jfmpc.jfmpc_78_18.BiesalskiHK
Carpagnano, Quaranta, Zito, Buonamico, Vitamin D deficiency as a predictor of poor prognosis in patients with acute respiratory failure due to COVID-19, J Endocrinol Invest
Chiodini, Gatti, Soranna, Merlotti, Mingiano, None
Clark, Mcdonagh, Mcmanus, Martin, None
Dankers, Colin, Lubberts, None
Dirosa, Malaguarnera, Nicoletti, Malaguarnera, Dror et al., Vitamin D in autoimmunity: molecular mechanisms and therapeutic potential, Immunol
Ghasemian, Shamshirian, Heydari, Malekan, Alizadeh-Navaei, ): 236. Grant WB (2008) Variations in vitamin D production could possibly explain the seasonality of childhood respiratory infections in Hawaii, Pediatr Infect Dis J, doi:10.1101/2020.06.05.20123554
Heidari, Mohammadi, Fathi, Cigary, Alisamir et al., Association of vitamin D status with COVID-19 disease severity in pediatric patients: A retrospective observational study, Health Sci Rep
Hernández, Nan, Fernandez-Ayala, García-Unzueta, Hernández et al., Vitamin D status in hospitalized patients with SARS-CoV-2 infection, J Clin Endocrinol Metab
Holick, Vitamin D deficiency, N Engl J Med
Jakovac, COVID-19 and vitamin D: Is there a link and an opportunity for intervention?, Am J Physiol Endocrinol Metab
Jordan, Siuka, Rotovnik, Pfeifer, None
Jose, Manuel, COVID-19 cytokine storm: the interplay between inflammation and coagulation, Lancet Respir Med
Lappe, Travers-Gustafson, Davies, Recker, Heaney, Vitamin D and calcium supplementation reduces cancer risk: Results of a randomized trial, Am J Clin Nutr
Li, Guan, Wu, Wang, Zhou, Early transmission dynamics in Wuhan, China, of novel coronavirusinfected pneumonia, N Engl J Med
Mandal, Pattanayak, Dietary modulation with fatty acids: a potential way to overcome COVID-19, Explor Anim Med Res
Manna, Novel coronavirus vulnerability: Metabolic derangements and altered dehydrogenase enzyme activities are central to the virus pathogenesis in human, bat and other animals, Explor Anim Med Res, doi:10.52635/eamr/
Marik, Kory, Varon, Does vitamin D status impact mortality from SARS-CoV-2 infection?, Med Drug Discov
Mathieu, Gysemans, Giulietti, Bouillon, Vitamin D and diabetes, Diabetologia
Moore, June, Cytokine release syndrome in severe COVID-19, Science
Nebhinani, Sharma, Suthar, Role of Vitamin D supplementation in patients with depressive disorders and hypovitaminosis D: A longitudinal study, J Mental Health Hum Behav
Nimavat, Singh, Singh, Singh, Sinha, Prevention and control of diabetes by intake of succulent biomedicines and following of designed lifestyle: A ready plan for execution, Int J Sci Res Updates, doi:10.1016/j.amsu.2021.102661.PattanayakS(2022
Oliveira, Da, Santana, Vitamin D deficiency aggravates COVID-19: systematic review and metaanalysis, Crit Rev Food Sci Nutr
Pinzon, Pradana, Vitamin D deficiency among patients with COVID-19: case series and recent literature review, Trop Med Health
Rhodes, Dunstan, Laird, Subramanian, Kenny, None
Roy, Lakshmy, Tarik, Tandon, Reddy, Independent association of severe Vitamin D deficiency as a risk of acute myocardial infarction in Indians, Indian Heart J
Saha, Ghosh, Ghosh, Vashistha, Aich et al., Vitamin D status in Covid-19 patients admitted to the critical care unit of an Eastern India hospital, Explor Anim Med Res
Singh, Nimavat, Singh, Ahmad, Sinha, Prevalence of low level of vitamin D among COVID-19 patients and associated risk factors in India -a hospital-based study, Int J Gen Med
Sooriyaarachchi, Jeyakumar, King, Jayawardena, Impact of Vitamin D deficiency on COVID-19, Clin Nutr ESPEN
Thacher, Clarke, Vitamin D insufficiency, Mayo Clin Proc
Vimaleswaran, Berry, Lu, Tikkanen, Pilz, Causal relationship between obesity and Vitamin D status: Bidirectional mendelian randomization analysis of multiple cohorts, PLoS Med
Wang, Pencina, Booth, Jacques, Ingelsson, Vitamin D deficiency and risk of cardiovascular disease
Xu, Shi, Wang, Zhang, Huang, Coronavirus disease 2019 (COVID-19) and the renin-angiotensin system: a closer look at the angiotensin-converting enzyme 2 (ACE2), Lancet Respir Med
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