Determination of Serum Vitamin D Levels in Patients with COVID-19
Haniyeh Bashi, Zadeh Fakhar, Nasim Kazemi Noraldinvand, Forouzan Rostami, Shaghyegh Rangraz, Parnian Sadat
Background: In 2019, the first cases of an acute respiratory infectious disease were announced in the city of Wuhan, China. In places where the speed of transmission and the resulting high prevalence and death from this virus is high, it is important to find things that help prevent and reduce the symptoms and complications of the disease, one of these things. Things are serum levels of vitamin D. As a result of this study, serum levels of vitamin D were measured in patients with Covid-19. Methods: From December to March of 1400, 100 samples of people hospitalized in Khurshid laboratory were examined to identify the RNA of the Covid-19 virus by Real Time PCR method and at the same time to check the serum levels of vitamin D. The data was statistically analyzed using SPSS software.
Results: The average age of the patients was between 12.45 and 40.8 years. Comparison the two Covid-19 positive and negative groups in terms of symptoms, it was found that the patients with RH positive had more positive PCR percentage and a significant difference was reported between RH positive and Covid-19 (p=0.006). In comparing the relationship between disease symptoms and the rate of PCR positive reports of gastrointestinal symptoms, history of significant disease, cough, fever, a significant difference was reported (p<0.001). Also, 50% of the samples were PCR positive. Based on the t-test, a significant difference was reported between the serum levels of vitamin D and Covid-19 (p<0.001).
Conclusion: The results showed that the vitamin D is an acceptable protective factor against Covid-19 infection and its deficiency increases the probability of infection.
Funding Information No funding was provided from the authorities.
Ethics approval and consent to participate All the procedures were approved by the institutional and/or national research committee and in compliance with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Additionally, this study obtained the approval of the Ethics Committee of Azad University of Medical Sciences, Iran (Code no: IR.IAU.CHALUS.REC.1400.122).
Conflict of interest The authors declare no conflict of interest.
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