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Influence of Strict Lockdown on Vitamin D Deficiency in Pregnant Women: A Word of Caution

Agüero-Domenech et al., Nutrients, doi:10.3390/nu15081972
Apr 2023  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now known with p < 0.00000000001 from 120 studies, recognized in 8 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,200+ studies for 70+ treatments. c19early.org
Retrospective 886 pregnant women in Spain, showing that strict lockdowns increased the risk of vitamin D deficiency.
Agüero-Domenech et al., 19 Apr 2023, retrospective, Spain, peer-reviewed, survey, 9 authors, study period 15 March, 2020 - 15 May, 2020. Contact: eduardobernabeu@gva.es (corresponding author), nuria.aguero@umh.es, sarrion_ana@gva.es, jover_sil@gva.es, baranda_jav@gva.es, garcia_mjter@gva.es, antonio@garciavalentin.es, ernesto.cortes@umh.es, vgil@umh.es.
This PaperVitamin DAll
Influence of Strict Lockdown on Vitamin D Deficiency in Pregnant Women: A Word of Caution
Nuria Agüero-Domenech, Eduardo Bernabeu, Antonio García-Valentín, Ana Sarrión, Silvia Jover, Javier Baranda, Ernesto Cortés-Castell, Vicente Gil-Guillén, María J García-Teruel
Nutrients, doi:10.3390/nu15081972
The main source of vitamin D results from skin sunlight exposure. Vitamin D deficiency (VDD) is linked to several adverse events during pregnancy. While performing a cross-sectional study with 886 pregnant women in Elda (Spain) from September 2019 to July 2020 to determine the association of VDD with gestational diabetes mellitus in relation to body mass index, a strict lockdown (SL) due to the COVID-19 pandemic was declared from 15 March 2020 to 15 May 2020. To determine if VDD prevalence in the local population of pregnant women was influenced by SL, a retrospective cross-sectional study was conducted to estimate the prevalence odds ratio (POR) for the association of VDD and SL. A crude logistic regression model was calculated, and then further adjusted by the biweekly measured vitamin D-specific UVB dose in our geographical area. The POR during SL was 4.0 (95%CI = 2.7-5.7), with a VDD prevalence of 77.8% in the quarantine period. Our results revealed that VDD prevalence in pregnant women was influenced by SL. This valuable information could guide us in future if public officials order the population to stay indoors for any given reason.
Informed Consent Statement: Informed consent was obtained from all subjects involved in this study. Data Availability Statement: Not applicable. Acknowledgments: The authors thank all the pregnant women included in this study. They acknowledge the doctors and midwives in the Department of Gynaecology and Obstetrics in the Hospital General Universitario Elda, extending a special mention to the High-Risk Pregnancies Clinic personnel (Guadalupe Díaz-García). The authors also recognise the Laboratory Department for their collaboration. Conflicts of Interest: The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analysis, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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