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Influence of Strict Lockdown on Vitamin D Deficiency in Pregnant Women: A Word of Caution

Agüero-Domenech et al., Nutrients, doi:10.3390/nu15081972
Agüero-Domenech et al., Influence of Strict Lockdown on Vitamin D Deficiency in Pregnant Women: A Word of Caution, Nutrients, doi:10.3390/nu15081972
Apr 2023   Source   PDF  
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Retrospective 886 pregnant women in Spain, showing that strict lockdowns increased the risk of vitamin D deficiency.
Agüero-Domenech et al., 19 Apr 2023, retrospective, Spain, peer-reviewed, survey, 9 authors, study period 15 March, 2020 - 15 May, 2020.
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AI generated summary. Current AI models can provide useful summaries for non-experts, but may be inaccurate and have limited ability to analyze larger context such as the entire evidence base for vitamin D.

Strict lockdowns increase the risk of vitamin D deficiency in pregnant women.

  • Vitamin D is essential for many biological functions, including pregnancy and bone health.
  • Vitamin D deficiency (VDD) is linked to several adverse events during pregnancy, such as preeclampsia, gestational diabetes mellitus (GDM), preterm birth, and caesarean delivery.
  • The COVID-19 pandemic required governments around the world to adopt special measures to control social interaction, including strict lockdowns.
  • Strict lockdowns reduce people's exposure to sunlight, which is a major source of vitamin D.
  • A study of pregnant women in Spain found that the prevalence of VDD increased significantly during the strict lockdown.
  • The study's findings suggest that strict lockdowns may increase the risk of VDD in pregnant women.
  • Pregnant women should take steps to maintain adequate vitamin D levels during strict lockdowns, such as taking supplements and getting regular sunlight exposure.

The study's findings are concerning, as they suggest that strict lockdowns may have a negative impact on the health of pregnant women. It is important for pregnant women to take steps to maintain adequate vitamin D levels during these times, such as taking supplements and getting regular sunlight exposure.

Influence of Strict Lockdown on Vitamin D Deficiency in Pregnant Women: A Word of Caution
Nuria Agüero-Domenech, Eduardo Bernabeu, Antonio García-Valentín, Ana Sarrión, Silvia Jover, Javier Baranda, Ernesto Cortés-Castell, Vicente Gil-Guillén, María J García-Teruel
Nutrients, doi:10.3390/nu15081972
The main source of vitamin D results from skin sunlight exposure. Vitamin D deficiency (VDD) is linked to several adverse events during pregnancy. While performing a cross-sectional study with 886 pregnant women in Elda (Spain) from September 2019 to July 2020 to determine the association of VDD with gestational diabetes mellitus in relation to body mass index, a strict lockdown (SL) due to the COVID-19 pandemic was declared from 15 March 2020 to 15 May 2020. To determine if VDD prevalence in the local population of pregnant women was influenced by SL, a retrospective cross-sectional study was conducted to estimate the prevalence odds ratio (POR) for the association of VDD and SL. A crude logistic regression model was calculated, and then further adjusted by the biweekly measured vitamin D-specific UVB dose in our geographical area. The POR during SL was 4.0 (95%CI = 2.7-5.7), with a VDD prevalence of 77.8% in the quarantine period. Our results revealed that VDD prevalence in pregnant women was influenced by SL. This valuable information could guide us in future if public officials order the population to stay indoors for any given reason.
Informed Consent Statement: Informed consent was obtained from all subjects involved in this study. Data Availability Statement: Not applicable. Acknowledgments: The authors thank all the pregnant women included in this study. They acknowledge the doctors and midwives in the Department of Gynaecology and Obstetrics in the Hospital General Universitario Elda, extending a special mention to the High-Risk Pregnancies Clinic personnel (Guadalupe Díaz-García). The authors also recognise the Laboratory Department for their collaboration. Conflicts of Interest: The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analysis, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.
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