Hematological Parameters in COVID-19 Patients: Association with Severity of the Disease
A A Abdulla, Abdulaali Abed, Abbas Fadhel, Awadh
doi:10.22092/ARI.2022.358363.2208
Introduction The novel coronavirus (COVID-19) is responsible for severe acute respiratory coronavirus syndrome (SARS-CoV-2; previously known as 2019-nCoV) and has symptoms ranging from extremely mild to lifethreatening (1). On January 30, 2020, the World Health Organization declared COVID-19 a global public health emergency due to the disease's rapid spread, which was already seen in December 2019 and January 2020 (2). Some complications include pneumonia, acute severe respiratory distress syndrome, renal insufficiency, and death (3). Excessive inflammatory responses to SARS-CoV-2 are thought to impact disease severity and mortality in COVID-19-infected patients significantly. It has been linked to high levels of circulating cytokines, severe lymphopenia, and significant mononuclear cell infiltration in the lungs, spleen, heart, kidney, and lymph nodes (2). The World Health Organization (WHO) classified cases into three severity levels based on clinical symptoms: mild, severe, and critical. The Creactive protein (CRP) is a systemic inflammatory response characterized by increased pro-inflammatory cytokines, such as interleukin-6. It can be triggered by
Authors' Contribution
Ethics The study protocol was reviewed by the University Committee on health studies which uses the guidelines of MOH and MOHSER, and approved under number 389 in / 2020.
Conflict of Interest The authors declare that they have no conflict of interest.
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