Association of Vitamin D receptor gene polymorphisms and clinical/severe outcomes of COVID-19 patients
Rasoul Abdollahzadeh, Mohammad Hossein Shushizadeh, Mina Barazandehrokh, Sepideh Choopani, Asaad Azarnezhad, Sahereh Paknahad, Maryam Pirhoushiaran, S Zahra Makani, Razieh Zarifian Yeganeh, Ahmed Al-Kateb, Roozbeh Heidarzadehpilehrood
Infection, Genetics and Evolution, doi:10.1016/j.meegid.2021.105098
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre -including this research content -immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
Conflict of Interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Highlights Growing evidence indicated the critical impacts of vitamin D (VD) in prognosis of COVID-19 patients. Significant associations were disclosed for some of the SNPs with severity, signs, symptoms, and coexisting pathologic conditions. VDR gene polymorphisms might thus allow the prioritization of those at greater risk for COVID-19. J o u r n a l P r e -p r o o f
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