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Clinical review of COVID-19 patients presenting to a quaternary care private hospital in South India: A retrospective study

Mohandas et al., Clinical Epidemiology and Global Health, doi:10.1016/j.cegh.2021.100751, Apr 2021
https://c19early.org/mohandas2.html
Mortality -429% Improvement Relative Risk Tocilizumab  Mohandas et al.  LATE TREATMENT Is late treatment with tocilizumab beneficial for COVID-19? Retrospective 3,345 patients in India Higher mortality with tocilizumab (p<0.000001) c19early.org Mohandas et al., Clinical Epidemiology.., Apr 2021 Favorstocilizumab Favorscontrol 0 0.5 1 1.5 2+
Retrospective 3,345 hospitalized patients in India, showing higher mortality with remdesivir and tocilizumab in unadjusted results. Confounding by indication is likely.
This study is excluded in meta analysis: substantial unadjusted confounding by indication likely; unadjusted results with no group details.
Study covers tocilizumab, remdesivir, and HCQ.
risk of death, 428.6% higher, RR 5.29, p < 0.001, treatment 40 of 231 (17.3%), control 102 of 3,114 (3.3%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Mohandas et al., 26 Apr 2021, retrospective, India, peer-reviewed, 6 authors.
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Late treatment
is less effective
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