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All Studies   Meta Analysis    Recent:   

Vitamin C for COVID-19: real-time meta analysis of 70 studies (68 treatment studies and 2 sufficiency studies)

Covid Analysis
Mar 2024  
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Vitamin C for COVID-19
7th treatment shown to reduce risk in September 2020
 
*, now known with p = 0.00000011 from 68 studies, recognized in 10 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,900+ studies for 60+ treatments. c19early.org
Statistically significant lower risk is seen for mortality, ICU admission, hospitalization, and recovery. 23 studies from 23 independent teams in 12 countries show statistically significant improvements.
Meta analysis using the most serious outcome reported shows 21% [14‑27%] lower risk. Results are similar for Randomized Controlled Trials, higher quality studies, and peer-reviewed studies. Clinical outcomes suggest benefit while viral and case outcomes do not, consistent with an intervention that aids the immune system or recovery but may have limited antiviral effects. Early treatment is more effective than late treatment.
Results are robust — in exclusion sensitivity analysis 28 of 68 studies must be excluded to avoid finding statistically significant efficacy in pooled analysis.
7 RCTs with 1,468 patients have not reported results (up to 3 years late).
The European Food Safety Authority has found evidence for a causal relationship between the intake of vitamin C and optimal immune system function Galmés, Galmés (B).
No treatment or intervention is 100% effective. All practical, effective, and safe means should be used based on risk/benefit analysis. Multiple treatments are typically used in combination, and other treatments are more effective. The quality of non-prescription supplements can vary widely and the quantity of the active ingredient may be significantly lower than stated Chanyandura, Crawford, Crighton.
All data to reproduce this paper and sources are in the appendix. Other meta analyses show significant improvements with vitamin C for mortality Bhowmik, Kow, Kow (B), Olczak-Pruc, progression Sun, severity Bhowmik, and cases Xu.
6 meta analyses show significant improvements with vitamin C for mortality Bhowmik, Kow, Kow (B), Olczak-Pruc, progression Sun, severity Bhowmik, and cases Xu.
Covid Analysis et al., Mar 2024, preprint, 1 author.
This PaperVitamin CAll
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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