Statistically significant lower risk is seen for mortality, ventilation, hospitalization, progression, recovery, and viral clearance. 18 studies from 16 independent teams in 8 countries show statistically significant improvements.
Meta analysis using the most serious outcome reported shows 42% [30‑52%] lower risk. Results are similar for Randomized Controlled Trials, higher quality studies, and peer-reviewed studies.
Results are robust — in exclusion sensitivity analysis 24 of 26 studies must be excluded to avoid finding statistically significant efficacy in pooled analysis.
Studies typically use advanced formulations for greatly improved bioavailability.
No treatment or intervention is 100% effective. All practical, effective, and safe means should be used based on risk/benefit analysis. Multiple treatments are typically used in combination, and other treatments may be more effective. The quality of non-prescription supplements can vary widely Crawford, Crighton.
All data to reproduce this paper and sources are in the appendix. Other meta analyses show significant improvements with curcumin for mortality Kow, Shafiee, Shojaei, Vahedian-Azimi, hospitalization Shojaei, Vahedian-Azimi, recovery Shafiee, and symptoms Vahedian-Azimi.
Covid Analysis et al., Apr 2024, preprint, 1 author.