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All Studies   Meta Analysis   Recent: 
Povidone-Iodine for COVID-19: real-time meta analysis of 20 studies
Covid Analysis (Preprint) (meta analysis)
Dec 2022    Source   PDF   Share   Tweet
• Statistically significant improvements are seen for mortality, hospitalization, cases, and viral clearance. 10 studies from 10 independent teams in 8 different countries show statistically significant improvements in isolation (7 for the most serious outcome).
• Meta analysis using the most serious outcome reported shows 51% [37‑61%] improvement. Results are similar for Randomized Controlled Trials, similar after exclusions, and similar for peer-reviewed studies. Early treatment is more effective than late treatment.
• Results are robust — in exclusion sensitivity analysis 16 of 20 studies must be excluded to avoid finding statistically significant efficacy in pooled analysis.
• Some studies only test short term viral load after a single application. Excessive use of PVP-I could affect thyroid function.
• No treatment, vaccine, or intervention is 100% effective and available. All practical, effective, and safe means should be used based on risk/benefit analysis. Multiple treatments are typically used in combination, and other treatments may be more effective. Only 15% of povidone-iodine studies show zero events with treatment.
• All data to reproduce this paper and sources are in the appendix. Other meta analyses for povidone-iodine can be found in [Hasan, Idrees], showing significant improvements for viral clearance and viral load.
Covid Analysis et al., Dec 2022, preprint, 1 author.
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Please send us corrections, updates, or comments. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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