Bemnifosbuvir for COVID-19: real-time meta analysis of 4 studies

Covid Analysis, Dec 2025
Meta analysis using the most serious outcome reported shows 32% [-74‑73%] lower risk, without reaching statistical significance. Results are better for peer-reviewed studies. Currently all studies are RCTs.
2 studies (both from the same team/sponsor) show significant benefit.
Control Bemnifosbuvir
Currently there is limited data, with only 11 control events for the most serious outcome in trials to date. All studies to date are from the same group.
No treatment is 100% effective. Protocols combine safe and effective options with individual risk/benefit analysis and monitoring. Other treatments are more effective. All data and sources to reproduce this analysis are in the appendix.
Covid Analysis et al., Dec 2025, preprint, 1 author.
Please send us corrections, updates, or comments. c19early involves the extraction of 200,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. IMA and WCH provide treatment protocols.
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