Significantly lower risk is seen for cases and viral clearance. 6 studies from 5 independent teams in 5 countries show significant benefit.
Meta analysis using the most serious outcome reported shows 30% [1‑50%] lower risk. Results are similar for Randomized Controlled Trials and higher quality studies and worse for peer-reviewed studies. Early treatment is more effective than late treatment.
Mortality results are negative, however all results to date are from late treatment trials.
In exclusion sensitivity analysis, statistical significance is lost after excluding only one of 13 studies in pooled analysis.
No treatment is 100% effective. Protocols combine safe and effective options with individual risk/benefit analysis and monitoring. Other treatments are more effective. Nitric Oxide may affect the natural microbiome, especially with prolonged use. All data and sources to reproduce this analysis are in the appendix.
Covid Analysis et al., May 2025, preprint, 1 author.
