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c19early.org COVID-19 treatment researchEnsovibepEnsovibep (more..)
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Ensovibep for COVID-19: real-time meta analysis of 2 studies

Covid Analysis, May 2025
https://c19early.org/caevmeta.html
Significantly lower risk is seen for hospitalization. One study shows significant benefit.
Meta analysis using the most serious outcome reported shows 47% [-108‑87%] lower risk, without reaching statistical significance. Early treatment is more effective than late treatment. Currently all studies are RCTs.
Control Ensovibep
Currently there is limited data, with only 885 patients and only 45 control events for the most serious outcome in trials to date. Studies to date are from only 2 different groups.
Ensovibep requires IV infusion, but may be less variant dependent than monoclonal antibodies.
No treatment is 100% effective. Protocols combine safe and effective options with individual risk/benefit analysis and monitoring. All data and sources to reproduce this analysis are in the appendix.
Covid Analysis et al., May 2025, preprint, 1 author.
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. IMA and WCH provide treatment protocols.
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