Intensive Treatment With Ivermectin and Iota-Carrageenan as Pre-exposure Prophylaxis for COVID-19 in Health Care Workers From Tucuman, Argentina
tive effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes.
Rossana E. Chahla, MD, PhD  1  Luis Medina Ruiz, MD  2  Eugenia S. Ortega, MSc 3 Marcelo F. Morales, RN  4  Francisco Barreiro, MD  5  Alexia George, MD  5  Cesar Mancilla, RN 4 Sylvia D' Amato, RN  4  Guillermo Barrenechea, MSc  3  Daniel G. Goroso, PhD
References
Abd-Elsalam, Noor, Badawi, Clinical study evaluating the efficacy of ivermectin in COVID-19 treatment: A randomized controlled study
Alam, Murshed, Gomes, Ivermectin as pre-exposure prophylaxis for COVID-19 among healthcare providers in a selected tertiary hospital in dhakaan observational study, Eur J Med Heal Sci
Ashburn, Thor, Drug repositioning: identifying and developing new uses for existing drugs, Nat Rev Drug Discov
Caly, Druce, Catton, Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect , the company' s public news and information, Antivir Res
Caly, Wagstaff, Jans, Nuclear trafficking of proteins from RNA viruses: potential target for antivirals?, Antivir Res
Chaccour, Casellas, Matteo, The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with nonsevere COVID-19: a pilot, double-blind, placebocontrolled, randomized clinical trial, EClinicalMedicine
Chaccour, Ruiz-Castillo, Richardson, The sars-cov-2 ivermectin navarra-isglobal trial (saint) to evaluate the potential of ivermectin to reduce covid-19 transmission in low risk, non-severe covid-19 patients in the first 48 hours after symptoms onset: a structured summary of a study protocol, Trials
Chahla, Prophylaxis covid-19 in health workers through intensive treatment with ivermectin and iotacarrageenan (Ivercar-Tuc), ClinicalTrials
Chong, Sullivan, New uses for old drugs, Nature
H Ector, Roberto, Psaltis, Study of the efficacy and safety of topical ivermectin + iota-carrageenan in the prophylaxis against COVID-19 in health personnel, J Biomed Res Clin Investig
Hirsch, Hector, Covid 19 and ivermectin prevention and treatment update, J Infect Dis Trav Med
Kory, Meduri, Varon, Review of the emerging evidence demonstrating the efficacy of ivermectin in the prophylaxis and treatment of COVID-19, Am J Ther
Krolewiecki, Lifschitz, Moragas, Antiviral effect of high-dose ivermectin in adults with COVID-19: A proof-of-concept randomized trial, EClinicalMedicine
Liu, Fang, Reagan, In silico drug repositioning: what we need to know, Drug Discov Today
Shouman, Hegazy, Nafae, Use of ivermectin as a potential chemoprophylaxis for COVID-19 in Egypt: a randomized clinical trial, J Clin Diagn Res
DOI record:
{
  "DOI": "10.1097/mjt.0000000000001433",
  "ISSN": [
    "1075-2765"
  ],
  "URL": "http://dx.doi.org/10.1097/MJT.0000000000001433",
  "author": [
    {
      "affiliation": [],
      "family": "Chahla",
      "given": "Rossana E.",
      "sequence": "first"
    },
    {
      "affiliation": [],
      "family": "Medina Ruiz",
      "given": "Luis",
      "sequence": "additional"
    },
    {
      "affiliation": [],
      "family": "Ortega",
      "given": "Eugenia S.",
      "sequence": "additional"
    },
    {
      "affiliation": [],
      "family": "Morales, RN",
      "given": "Marcelo F.",
      "sequence": "additional"
    },
    {
      "affiliation": [],
      "family": "Barreiro",
      "given": "Francisco",
      "sequence": "additional"
    },
    {
      "affiliation": [],
      "family": "George",
      "given": "Alexia",
      "sequence": "additional"
    },
    {
      "affiliation": [],
      "family": "Mancilla, RN",
      "given": "Cesar",
      "sequence": "additional"
    },
    {
      "affiliation": [],
      "family": "D' Amato, RN",
      "given": "Sylvia",
      "sequence": "additional"
    },
    {
      "affiliation": [],
      "family": "Barrenechea",
      "given": "Guillermo",
      "sequence": "additional"
    },
    {
      "affiliation": [],
      "family": "Goroso",
      "given": "Daniel G.",
      "sequence": "additional"
    },
    {
      "affiliation": [],
      "family": "Peral de Bruno",
      "given": "Maria",
      "sequence": "additional"
    }
  ],
  "container-title": "American Journal of Therapeutics",
  "content-domain": {
    "crossmark-restriction": false,
    "domain": []
  },
  "created": {
    "date-parts": [
      [
        2021,
        9,
        2
      ]
    ],
    "date-time": "2021-09-02T00:35:39Z",
    "timestamp": 1630542939000
  },
  "deposited": {
    "date-parts": [
      [
        2021,
        9,
        7
      ]
    ],
    "date-time": "2021-09-07T20:00:46Z",
    "timestamp": 1631044846000
  },
  "indexed": {
    "date-parts": [
      [
        2022,
        7,
        11
      ]
    ],
    "date-time": "2022-07-11T06:51:07Z",
    "timestamp": 1657522267235
  },
  "is-referenced-by-count": 5,
  "issue": "5",
  "issued": {
    "date-parts": [
      [
        2021,
        8,
        16
      ]
    ]
  },
  "journal-issue": {
    "issue": "5",
    "published-print": {
      "date-parts": [
        [
          2021
        ]
      ]
    }
  },
  "language": "en",
  "link": [
    {
      "URL": "https://journals.lww.com/10.1097/MJT.0000000000001433",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "member": "276",
  "original-title": [],
  "page": "e601-e604",
  "prefix": "10.1097",
  "published": {
    "date-parts": [
      [
        2021,
        8,
        16
      ]
    ]
  },
  "published-online": {
    "date-parts": [
      [
        2021,
        9
      ]
    ]
  },
  "publisher": "Ovid Technologies (Wolters Kluwer Health)",
  "reference": [
    {
      "DOI": "10.1038/448645a",
      "article-title": "New uses for old drugs",
      "author": "Chong",
      "doi-asserted-by": "crossref",
      "first-page": "645",
      "journal-title": "Nature.",
      "key": "R1-20210907",
      "volume": "448",
      "year": "2007"
    },
    {
      "DOI": "10.1016/j.drudis.2012.08.005",
      "article-title": "In silico drug repositioning: what we need to know",
      "author": "Liu",
      "doi-asserted-by": "crossref",
      "first-page": "110",
      "journal-title": "Drug Discov Today",
      "key": "R2-20210907",
      "volume": "18",
      "year": "2013"
    },
    {
      "DOI": "10.1038/nrd1468",
      "article-title": "Drug repositioning: identifying and developing new uses for existing drugs",
      "author": "Ashburn",
      "doi-asserted-by": "crossref",
      "first-page": "673",
      "journal-title": "Nat Rev Drug Discov.",
      "key": "R3-20210907",
      "volume": "3",
      "year": "2004"
    },
    {
      "DOI": "10.1016/j.antiviral.2012.06.008",
      "article-title": "Nuclear trafficking of proteins from RNA viruses: potential target for antivirals?",
      "author": "Caly",
      "doi-asserted-by": "crossref",
      "first-page": "202",
      "journal-title": "Antivir Res",
      "key": "R4-20210907",
      "volume": "95",
      "year": "2012"
    },
    {
      "DOI": "10.1016/j.antiviral.2020.104787",
      "article-title": "Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect , the company' s public news and information",
      "author": "Caly",
      "doi-asserted-by": "crossref",
      "first-page": "104787",
      "journal-title": "Antivir Res",
      "key": "R5-20210907",
      "volume": "178",
      "year": "2020"
    },
    {
      "DOI": "10.1097/MJT.0000000000001377",
      "article-title": "Review of the emerging evidence demonstrating the efficacy of ivermectin in the prophylaxis and treatment of COVID-19",
      "author": "Kory",
      "doi-asserted-by": "crossref",
      "first-page": "e299",
      "journal-title": "Am J Ther.",
      "key": "R6-20210907",
      "volume": "28",
      "year": "2021"
    },
    {
      "DOI": "10.1016/j.eclinm.2020.100720",
      "article-title": "The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: a pilot, double-blind, placebo-controlled, randomized clinical trial",
      "author": "Chaccour",
      "doi-asserted-by": "crossref",
      "first-page": "100720",
      "journal-title": "EClinicalMedicine.",
      "key": "R7-20210907",
      "volume": "3",
      "year": "2021"
    },
    {
      "DOI": "10.1016/j.eclinm.2021.100959",
      "article-title": "Antiviral effect of high-dose ivermectin in adults with COVID-19: A proof-of-concept randomized trial",
      "author": "Krolewiecki",
      "doi-asserted-by": "crossref",
      "first-page": "100959",
      "journal-title": "EClinicalMedicine.",
      "key": "R8-20210907",
      "volume": "37",
      "year": "2021"
    },
    {
      "DOI": "10.31546/2633-8653.1007",
      "article-title": "Study of the efficacy and safety of topical ivermectin + iota-carrageenan in the prophylaxis against COVID-19 in health personnel",
      "author": "Héctor",
      "doi-asserted-by": "crossref",
      "first-page": "1007",
      "journal-title": "J Biomed Res Clin Investig.",
      "key": "R9-20210907",
      "volume": "2",
      "year": "2020"
    },
    {
      "article-title": "Ivermectin as pre-exposure prophylaxis for COVID-19 among healthcare providers in a selected tertiary hospital in dhaka—an observational study",
      "author": "Alam",
      "first-page": "1",
      "journal-title": "Eur J Med Heal Sci.",
      "key": "R10-20210907",
      "volume": "2",
      "year": "2020"
    },
    {
      "article-title": "Use of ivermectin as a potential chemoprophylaxis for COVID-19 in Egypt: a randomized clinical trial",
      "author": "Shouman",
      "first-page": "27",
      "journal-title": "J Clin Diagn Res.",
      "key": "R11-20210907",
      "volume": "15",
      "year": "2021"
    },
    {
      "article-title": "Prophylaxis covid-19 in health workers through intensive treatment with ivermectin and iota-carrageenan (Ivercar-Tuc)",
      "author": "Chahla",
      "first-page": "NCT047017",
      "journal-title": "ClinicalTrials.gov.",
      "key": "R12-20210907",
      "volume": "20",
      "year": "2020"
    },
    {
      "DOI": "10.1186/s13063-020-04421-z",
      "article-title": "The sars-cov-2 ivermectin navarra-isglobal trial (saint) to evaluate the potential of ivermectin to reduce covid-19 transmission in low risk, non-severe covid-19 patients in the first 48 hours after symptoms onset: a structured summary of a study protocol",
      "author": "Chaccour",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "journal-title": "Trials",
      "key": "R13-20210907",
      "volume": "21",
      "year": "2020"
    },
    {
      "article-title": "Covid 19 and ivermectin prevention and treatment update",
      "author": "Hirsch",
      "first-page": "1",
      "journal-title": "J Infect Dis Trav Med.",
      "key": "R14-20210907",
      "volume": "4",
      "year": "2020"
    },
    {
      "article-title": "Clinical study evaluating the efficacy of ivermectin in COVID-19 treatment: A randomized controlled study [published online ahead of print, 2021 Jun 2]",
      "author": "Abd-Elsalam",
      "journal-title": "J Med Virol.",
      "key": "R15-20210907",
      "year": "2021"
    },
    {
      "DOI": "10.1186/s12941-020-00368-w",
      "article-title": "Ivermectin, a new candidate therapeutic against SARS-CoV-2/COVID-19",
      "author": "Sharun",
      "doi-asserted-by": "crossref",
      "first-page": "23",
      "journal-title": "Ann Clin Microbiol Antimicrob.",
      "key": "R16-20210907",
      "volume": "19",
      "year": "2020"
    },
    {
      "DOI": "10.3906/sag-2004-145",
      "article-title": "Antiviral treatment of covid-19",
      "author": "Şimşek Yavuz",
      "doi-asserted-by": "crossref",
      "first-page": "611",
      "journal-title": "Turkish J Med Sci.",
      "key": "R17-20210907",
      "volume": "50",
      "year": "2020"
    },
    {
      "DOI": "10.1097/MJT.0000000000001402",
      "article-title": "Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines",
      "author": "Bryant",
      "doi-asserted-by": "crossref",
      "first-page": "e434",
      "journal-title": "Am J Ther.",
      "key": "R18-20210907",
      "volume": "28",
      "year": "2021"
    }
  ],
  "reference-count": 18,
  "references-count": 18,
  "relation": {},
  "resource": {
    "primary": {
      "URL": "https://journals.lww.com/10.1097/MJT.0000000000001433"
    }
  },
  "score": 1,
  "short-title": [],
  "source": "Crossref",
  "subject": [
    "Pharmacology (medical)",
    "Pharmacology",
    "General Medicine"
  ],
  "subtitle": [],
  "title": "Intensive Treatment With Ivermectin and Iota-Carrageenan as Pre-exposure Prophylaxis for COVID-19 in Health Care Workers From Tucuman, Argentina",
  "type": "journal-article",
  "volume": "28"
}