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A Multi-Center, Randomized, Double-Blind, Placebo- Controlled Clinical Trial of the Safety and Efficacy of Convalescent Plasma for the Treatment of COVID-19 in Hospitalized Patients in Lagos State

Abayomi et al., PACTR202006760881890, LACCPT, PACTR202006760881890, Nov 2021
https://c19early.org/abayomi2.html
Mortality -17% improvement lower risk ← → higher risk Conv. Plasma  LACCPT  LATE TREATMENT RCT Is late treatment with convalescent plasma beneficial? Double-blind RCT 22 patients in Nigeria Trial underpowered to detect differences c19early.org Abayomi et al., PACTR202006760881890, Nov 2021 0 0.5 1 1.5 2+ RR
RCT 22 hospitalized patients, show no significant difference in mortality with convalescent plasma. Results are from Axfors et al..
risk of death, 16.7% higher, RR 1.17, p = 1.00, treatment 7 of 11 (63.6%), control 6 of 11 (54.5%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Abayomi et al., 20 Nov 2021, Double Blind Randomized Controlled Trial, placebo-controlled, Nigeria, peer-reviewed, 1 author, trial PACTR202006760881890 (LACCPT).
$0 $500 $1,000+ Efficacy vs. cost for COVID-19 treatment protocols c19early.org November 2025 Nigeria United Kingdom Russia USA Sudan Angola Colombia Kenya Mozambique Pakistan Argentina Vietnam Peru Philippines Spain Brazil Italy France Japan China Uzbekistan Nepal Ethiopia Iran Ghana Mexico South Korea Germany Bangladesh Saudi Arabia Algeria Morocco Yemen Poland India DR Congo Bolivia Taiwan Zambia Fiji Bosnia-Herzegovina Ukraine Côte d'Ivoire Bulgaria Greece Slovakia Singapore Iceland New Zealand Czechia Mongolia Israel Trinidad and Tobago Hong Kong North Macedonia Belarus Qatar Panama Serbia Nigeria favored low-cost treatments.The average efficacy of treatments was high.Low-cost treatments improve early treatment, andprovide complementary/synergistic benefits. More effective More expensive 75% 50% 25% ≤0%
$0 $500 $1,000+ Efficacy vs. cost for COVID-19treatment protocols worldwide c19early.org November 2025 Nigeria United Kingdom Russia USA Sudan Angola Colombia Kenya Mozambique Pakistan Argentina Vietnam Peru Philippines Spain Brazil Italy France Japan China Uzbekistan Nepal Ethiopia Iran Ghana Mexico South Korea Germany Bangladesh Saudi Arabia Algeria Morocco Yemen Poland India DR Congo Bolivia Taiwan Zambia Fiji Ukraine Côte d'Ivoire Eritrea Bulgaria Greece Slovakia Singapore New Zealand Malawi Czechia Mongolia Israel Trinidad and Tobago North Macedonia Belarus Qatar Panama Serbia Nigeria favored low-cost treatments.The average efficacy was high.Low-cost protocols improve early treatment,and add complementary/synergistic benefits. More effective More expensive 75% 50% 25% ≤0%
Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 200,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. IMA and WCH provide treatment protocols.
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